37 results about "Parylene C" patented technology

A coated coronary stent, comprising: a stainless steel sent framework coated with a primer layer of Parylene C; and a rapamycin-polymer coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.

The invention discloses a flexible retina emboss micro-electrode chip in the technical field of a micro-electronic-mechanical-system and a manufacture method thereof. In the method, parylene C is used as a flexible substrate and an insulating material for preparing a micro-electrode array which is formed by the arrangement of a plurality of micro-electrode sensing elements; simultaneously, an electrode lead and a lead welding point are manufactured to form the flexible retina emboss micro-electrode chip which is planted into the retina part of a human eye, can realize the safe and effective contact with the neuron of the retina, effectively reduce the stimulation to a pulse current, reduce the inserting damage to a biological tissue caused by the planting of the micro-electrode and can improve the effect of electric simulating and neural signal recording, thereby better recovering the visual function. In the invention, the parylene C is used as the substrate of a flexible electrode; the excellent electric insulating performance and mechanical performance thereof can improve the biocompatibility of the micro-electrode chip to a larger extent and have good stability for a long period. In the invention, an MEMS technique is adopted, thus realizing the integration of a functional unit and the flexible substrate of the micro-electrode.

Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides. The membranes can be used in vitro to grow monolayers of cells in a laboratory or in vivo as surgically implantable growth layers, such as to replace the Bruch's membrane in the eye. The application further provides an implantable cage-like apparatus for culturing cells comprising the parylene membrane.

A micro electromechanical (MEMS) antenna (36) is positioned on one side of a substrate and is connected to a MEMS switch comprising a capacitor bridge (46) and to a transmission line (42) by means of a thru hole or via (48) which forms an electrically conducting path through the substrate. This arrangement provides a common ground plane for the antenna and switch and shields the switch from the electromagnetic radiation received or transmitted from the antenna. The switch may comprise a topmost metal layer which extends across a bridge structure formed by a polymer layer (19). The polymer layer comprises poly-monochloro-para-xylene (parylene-C). Homogeneous or heterogeneous antenna array structures are implemented. The antenna arrays may include one or more different type of antennas with for example different shapes, rotations and reflections.

The invention discloses an EFI (exploding foil initiator) chip unit, a preparation method of the EFI chip unit, and an exploding foil initiation device based on the chip unit. The EFI chip unit comprises a ceramic substrate, a metal Ti / Cu layer, a Parylene C layer, an upper electrode Ti / W / Ti / Cu / Au, a Schottky diode and an Su8 acceleration chamber. The exploding foil initiation device comprises the EFI chip unit, a flying plate, an explosive cylinder, a printed circuit board base, a transmission line, a low-voltage chip capacitor and a high-voltage chip capacitor. The metal Ti / Cu layer serves as a lower electrode in a one-shot switch unit and as an exploding foil in an exploding foil initiation unit; the Parylene C layer serves as an insulation layer between the upper electrode and the lower electrode in the one-shot switch unit and as a flying plate layer of an exploding foil initiator in the exploding foil initiation unit; the acceleration chamber employs integrated manufacturing of Su8 photoresist; the technical process is reduced; the cost is low; the size is small; and the Schottky diode has a reverse breakdown characteristic, so that a switch can resist stray current and has intrinsic safety.

The invention discloses a method of regulating the surface wettability of a parylene c (PC) by virtue of surface patterning. The method comprises the following steps: ultrasonically washing the PC, and then drying the PC for standby application; processing the PC by virtue of air plasma for standby application; then smearing a polymer coating rich in polarity groups such as hydroxyl, carboxyl, amino group and the like on the surface of the PC, and drying; placing a patterned mask above the processed PC, and then carrying out a cross-linking reaction under the effect of UV / O3; after the cross-linking is completed, soaking in deionized water to wash out unreacted and ungrafted polymer coating rich in the polarity groups, and then drying to obtain a patterned PC with controllable surface wettability. According to the method of regulating the surface wettability of the PC by virtue of the surface patterning, the wettability is adjustable, a surface water contact angle can be regulated and designed in a range of 5 to 90 degrees, so that the surface wettability of the PC can be precisely designed according to the real requirement of different fields, and the yield of products is increased.

The invention provides an ultrathin flexible electric-heating tunable meta-material based on a three-dimensional Ohm structure and preparation of the same. The meta-material comprises a flexible parylene-C substrate and the three-dimensional Ohm structure, wherein the three-dimensional Ohm structure is composed of a lower parylene-C dielectric layer and an upper metal layer; and the three-dimensional Ohm structure is an Ohm ring or an Ohm circle. According to the invention, a dielectric medium and metal with different residual stresses and thermal expansion coefficients constitute the three-dimensional Ohm structure; and current or temperature control is used to control a relative rotation angle between the three-dimensional Ohm structure and the parylene-C substrate, so that continuous tuning is implemented to resonant frequency of electromagnetic responses. The meta-material provided by the invention has the advantages that structural design is novel; processing technologies are simple; a sacrificial layer is not needed; non-planar applications of the meta-material can be realized; and the continuous tuning can be implemented to the resonant frequency of the electromagnetic responses of the meta-material and incident electromagnetic waves.

Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides. The membranes can be used in vitro to grow monolayers of cells in a laboratory or in vivo as surgically implantable growth layers, such as to replace the Bruch's membrane in the eye. The application further provides an implantable cage-like apparatus for culturing cells comprising the parylene membrane.

The invention belongs to the technical field of optical fiber sensing and trace gas detection, and relates to a poly(monochloro-p-xylene)-based membrane resonance type gas sensor and a detection system. The gas sensor adopts a structure of an F-P interferometer; and an F-P cavity of the F-P interferometer is also a non-resonance photoacoustic tank a photoacoustic system. Parylene-C has relativelylow young modulus and relatively large elongation at break, so that a Parylene-C membrane prepared through a vacuum vapor phase polymerization deposition has the characteristics of strong coating property and high deposition uniformity; therefore Parylene-C membrane prepared through the vacuum vapor phase polymerization deposition has the characteristics of large radius and thin thickness. The inherent resonance frequency of the F-P interferometer is in direct proportion to the thickness of the diaphragm and is inversely proportional to the square of the radius of the diaphragm, so that the resonance frequency of the F-P interferometer can be as low as several tens of hertz. The invention provides a novel technical means for high-sensitivity long-distance gas telemetering in a narrow space.

A micro electromechanical (MEMS) antenna (36) is positioned on one side of a substrate and is connected to a MEMS switch comprising a capacitor bridge (46) and to a transmission line (42) by means of a thru hole or via (48) which forms an electrically conducting path through the substrate. This arrangement provides a common ground plane for the antenna and switch and shields the switch from the electromagnetic radiation received or transmitted from the antenna. The switch may comprise a topmost metal layer which extends across a bridge structure formed by a polymer layer. The polymer layer comprises poly-monochloro-para-xylene (parylene-C). Homogeneous or heterogeneous antenna array structures are implemented. The antenna arrays may include one or more different type of antennas with for example different shapes, rotations and reflections.

The invention provides a preparing method of a ring-shaped Kraft microelectrode based on self-stress bending. According to the method, in the preparing process, the ring-shaped bending based on the self stress is realized through controlling the thickness of Parylene-C layers and the heat treatment conditions and regulating the self-stress conditions of different Parylene-C layers, and a Kraft electrode is formed. The preparing method has the advantages that the operation is simple and convenient, and a series of annular Kraft electrodes in different diameters can be formed.

The invention relates to an applied technology of micro-robots in the fields of cell operation and cell separation, in particular to a micro-actuator driven by heating from electricity and a process for preparation. The micro-actuator driven by heating from electricity is composed of a polymeric material of Parylene C and electron-heating materials of titanium and platinum and is capable of realizing the operation of clamping cells under the fluid environment. The actuator is a multiple cantilever beam structure and is fixed on a silicon substrate, and each cantilever beam is a three-layer structure of parylene C clamping the electron-heating materials. The processing technique employs screen-printing technology of MEMS (micro-electro-mechanism system). The invention is capable of being electrically driven, and parylene C is taken as heat / electricity / fluid isolation material, then a heater formed by electron-heating materials is not exposed in the fluid, thereby having good biological adaptability and fluid environment adaptability, being capable of realizing cell operation and cell separation by controlling the temperature and providing automatic operation and application of localization detection, injection and measuring of cells.

A parylene C polymer that is electrically poled such that it is piezoelectric is presented. Methods for manufacturing the piezoelectric parylene C polymer with an optimal piezoelectric coefficient d33 are also disclosed. Actuators formed with piezoelectric parylene C are disclosed as well as sensor devices that incorporate piezoelectric parylene C using charge integrator circuits in which the integration time is longer than likely adiabatic temperature transients.

The present invention relates to the application of miniature robot technology in cell operation and separation, and is especially one new kind of thermally driven miniature executor based on Parylene C polymer material and capable of realizing cell operation in liquid environment. The miniature executor has multiple cantilever beam structure fixed on silicon substrate, and each of the cantilever beams is a three layer structure with Parylene C sandwiched resistive material. The miniature executor is prepared through one MEMS planar printing process. The present invention has electrothermal braking effect, and Parylene C as one kind of thermally, electrically and chemically isolating material may keep the heater of resistive material from exposing in liquid, resulting in excellent biocompatibility and environmental suitability. The present invention realizes cell operation and separation under controlled temperature and may be used in automatic cell location, detection, injection and measurement.

A coated coronary stent, comprising a stainless steel sent framework coated with a p1imer layer of Parylene C, and a rapamycin-polymer coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially unifom1ly dispersed within the rapamycin-polymer coating.

The invention relates to a multi-layer composite protection layer applied to PCB and a method. The multi-layer composite protection layer comprises a nano silicon dioxide coating, Parylene C coating,and epoxy resin coating which are arranged inside to outside, and the thickness of the Parylene C coating is 30-40 [mu]m. The application method comprises the steps of: 1) cleaning and dehumidifying the surface of a PCB; 2) socking the cleaned PCB into a nanosilicon dioxide liquid to obtain a PCB with a surface coated with nanosilicon dioxide; 3) coating a Parylene C material at the surface of thePCB with the surface coated with nanosilicon dioxide by employing a vacuum chemical vapor deposition method; and 4) obtaining the epoxy resin material at the surface of the PCB obtained in the step 3). The PCB is good in waterproof performance, can normally work in a soaking environment and has a good mechanical performance.

Embodiments include inflatable articles that include an interior surface adapted for being in contact with the inflation gas, the interior surface coated with a parylene barrier. The parylene barrier may be formed of parylene N, parylene C, parylene D, another substituted parylene or combinations thereof. In particular embodiments, the inflatable article is a tire. Other embodiments include inflatable articles having composite layers, wherein at least two of the composite layers include surfaces that interface with one another and a parylene coating applied to at least one of the interfacing surfaces.

The invention relates to the technical field of biological medicine and advanced manufacturing, and provides a flexible microporous membrane, a filtering device for filtering and removing nucleated cells including tumor cells in autoblood, a detection system comprising the filtering device, a liquid sample treatment system and an autoblood transfusion system. The filtering device comprises a filtering structure containing a Parylene C membrane, the Parylene C membrane contains uniform holes, and the permissible diameter range of the holes is 4 to 8 microns.

The present invention provides a biological material including a parylene C film; and first proteins which are adsorbed on the surface of the parylene C film. According to an embodiment of the present invention, the biological material further includes second proteins different from the first proteins adsorbed on the surface of the parylene C film. According to an embodiment of the present invention, the first proteins or the second proteins include BMP-2, fibronectin or PRP.

The invention discloses a waterproof structure of a wall embedded part and a construction method thereof. The waterproof structure of the wall embedded part comprises a first sealing block, a second sealing block and a waterproof layer, and the first sealing block and the second sealing block Set on the outside of the embedded part, the assembly formed by the three is set in the prefabricated rectangular hole of the structural wall, the inside of the rectangular hole is set with fine stone concrete, and the waterproof layer is set on the outside of the structural wall; The embedded parts protrude from the waterproof layer, the first sealing block is located at the junction of the fine stone concrete and the waterproof layer, and the second sealing block is arranged in the waterproof layer; the waterproof layer includes polyolefin, parylene C , Waterproofing agent and adhesive, polyolefin, Parylene C, waterproofing agent, the volume ratio of the adhesive is 75%: 5%: 8%: 12%. The technical solution provided by the invention has a reasonable structure and convenient construction, without opening holes in the formwork when the wall formwork is installed, reducing the construction process of applying the protective layer and effectively improving the construction efficiency.

An ablation probe which includes a probe body with a distal and proximal end, an ablation tip at the distal end of the probe body, an anode provided proximate to the ablation tip, a coaxial cable disposed within the probe body and coupled to the ablation tip and anode so that electromagnetic energy of a predetermined frequency is communicated thereto for dielectric heating of tissue, and a Parylene C coating on at least the ablation tip and anode to electrically isolate the ablation tip and anode from tissue without interference with microwave energy transmission through the probe to the tissue. The Parylene C is a vapor deposited coating on at least the ablation tip and anode to electrically isolate the ablation tip and anode from tissue.

The invention discloses a flexible retina emboss micro-electrode chip in the technical field of a micro-electronic-mechanical-system and a manufacture method thereof. In the method, parylene C is used as a flexible substrate and an insulating material for preparing a micro-electrode array which is formed by the arrangement of a plurality of micro-electrode sensing elements; simultaneously, an electrode lead and a lead welding point are manufactured to form the flexible retina emboss micro-electrode chip which is planted into the retina part of a human eye, can realize the safe and effective contact with the neuron of the retina, effectively reduce the stimulation to a pulse current, reduce the inserting damage to a biological tissue caused by the planting of the micro-electrode and can improve the effect of electric simulating and neural signal recording, thereby better recovering the visual function. In the invention, the parylene C is used as the substrate of a flexible electrode; the excellent electric insulating performance and mechanical performance thereof can improve the biocompatibility of the micro-electrode chip to a larger extent and have good stability for a long period. In the invention, an MEMS technique is adopted, thus realizing the integration of a functional unit and the flexible substrate of the micro-electrode.

The invention discloses a multi-channel micro-ring sensor and a preparation and use method thereof, the multi-channel micro-ring sensor comprises a sensing substrate, a waveguide micro-ring, a coating exposed sensing area and an optical fiber array, the waveguide micro-ring is manufactured on the sensing substrate by adopting a standard tape-out process, and the waveguide micro-ring comprises an input waveguide, two output waveguides and a micro-ring; according to the present invention, the multi-parameter detection purpose which can only be achieved through the traditional micro-fluidic channel is improved to the combination of the parylene C film hydrophobic effect and the microspotting instrument, such that the specific protein is fixed on the micro-ring surface through the one-step method so as to simplify the chip preparation and modification process, and the traditional micro-fluidic channel is adopted such that the size of the chip cannot be too small. The method does not depend on a microfluidic channel, the size of the chip is reduced, the higher integration level is achieved, meanwhile, the parylene C thin film one-step method is used for fixing the specific antibody, after detection is completed, parylene C can be removed, the chip is recycled, and the cost is reduced.

This disclosure relates to a razor blade with a lubricating coating composed of Parylene C and Parylene N. It also relates to a shaving cartridge comprising at least one blade with a lubricating coating composed of Parylene C and Parylene N. Furthermore, a method for coating a razor blade with a lubricating coating composed of Parylene C and Parylene N is described.

The invention discloses an explosive foil integrated chip based on low-temperature co-fired ceramics and a preparation process thereof. Explosive foil integrated chip includes: ceramic substrate, metal layer, flyer layer, acceleration chamber, charge tank and explosive column, and also includes metal vias in the ceramic substrate, paste, and pad area on the back and Pd / A structure such as an Ag layer that facilitates connection with other parts. The ceramic substrate is used as a reflective backplane in the integrated chip; the metal layer includes three parts: bridge area, transition area and conduction band; the flyer layer includes ceramic flyer, Parylene C / W‑Ti / Cu composite flyer; the function of the acceleration chamber is to provide acceleration space for the flyer; the charging groove provides precise positioning for the placement of the explosive column. Compared with the prior art, the present invention has the advantages of using low-temperature co-fired ceramic technology to make the explosive foil detonator more integrated and smaller in volume, which can realize mass production, improve product consistency, and greatly reduce costs .

The invention discloses a wall embedded part waterproof structure and a construction method thereof. The wall embedded part waterproof structure comprises a first sealing block, a second sealing blockand a waterproof layer; the first sealing block and the second sealing block are arranged on the outer side of an embedded part in a sleeving mode; an assembly formed by the first sealing block, thesecond sealing block and the waterproof layer is arranged in a rectangular hole prefabricated in a structural wall; fine aggregate concrete is arranged in the rectangular hole; the waterproof layer isarranged on the outer side of the structural wall body; the embedded part protrudes out of the waterproof layer; the first sealing block is located at the junction of the fine aggregate concrete andthe waterproof layer; and the second sealing block is arranged in the waterproof layer. The waterproof layer comprises polyolefin, parylene C, a waterproof agent and an adhesive, and the volume ratioof the polyolefin to the parylene C to the waterproof agent to the adhesive is 75%:5%:8%:12%. According to the technical scheme, the structure is reasonable, construction is convenient, a hole does not need to be formed in a wall formwork when the formwork is installed, the construction procedure of smearing a protective layer is reduced, and the construction efficiency is effectively improved.

The invention discloses a reusable optical biosensor chip and a method for realizing reuse of the optical biosensor chip, and relates to the field of biosensing. A parylene C film is attached to the surface of a nano structure of the optical biosensor chip, and the parylene C film is coupled with an antibody and an antigen; and the nanostructure of the optical biosensor chip is coupled with the antibody and the antigen thereof by using parylene C, and parylene C is removed after the detection is completed. The parylene C film is used as a coupling bridge between the optical biosensor chip nanostructure and the specific antibody, a specific parylene C growth thickness and a removal method are adopted, the surface property of the nanostructure is not influenced, parylene C can be grown on the chip again, and a spectral result shows that the spectrum of the chip after parylene C is removed completely coincides with that of an initial chip.

The invention belongs to the technical field of optical fiber sensing and trace gas detection, and relates to a membrane resonant gas sensor and a detection system based on polychlorop-xylene. The gas sensor adopts the structure of F-P interferometer, and the F-P cavity of the F-P interferometer is also the non-resonant photoacoustic cell of the photoacoustic system. Parylene-C has a low Young's modulus and a large elongation at break. The Parylene-C film prepared by vacuum vapor-phase polymerization deposition has the characteristics of strong conformality and good deposition uniformity. Therefore, vacuum vapor-phase polymerization is used. The Parylene-C film prepared by the deposition method can simultaneously have the characteristics of large radius and thin thickness. The natural resonance frequency of the F-P interferometer is proportional to the thickness of the diaphragm and inversely proportional to the square of the diaphragm radius, so the resonance frequency of the F-P interferometer can be as low as tens of Hz. The invention provides a new technical means for high-sensitivity long-distance gas telemetry in a narrow space.