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2 results about "Sapovirus" patented technology
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Sapovirus is a genetically diverse genus of single-stranded positive-sense RNA, non-enveloped viruses within the Caliciviridae family. Together with norovirus, sapoviruses are the most common cause of acute gastroenteritis (commonly called the "stomach flu" although it is not related to influenza) in humans and other animals. It is a monotypic taxon, containing only one species, Sapporo virus.
Porcine sapovirus isolates and immunogenic compositions therefrom
The present disclosure is directed to novel porcine sapoviruses (SaV) isolates, including SaV serially propagated in cell culture, all of which are useful in the preparation of immunogenic compositions and vaccines for treating and preventing disease in swine. The disclosure further provides characterization of pathogenicity and cross-protective immunity of contemporary porcine SaV isolates in weaned pigs, demonstrating that prior exposure to homologous strains provides greater protection against viral shedding than heterologous strains.
Owner:IOWA STATE UNIV RES FOUND INC
Methods and compositions for treating viral infections
PendingUS20260191924A1QuercitrinFagopyrum dibotrys
Nutraceutical compositions and methods of their use in treating Caliciviridae family viruses are provided. The viruses can be norovirus or sapovirus. An exemplary nutraceutical composition includes Fagopyrum dibotrys extract. Another nutraceutical composition for treating viral gastroenteritis includes 5, 7, 3′, 4′-tetrahydroxyflavan-3-ol C4-C8 dimers, quercetin, rutin, or a combination thereof. The nutraceutical compositions inhibit or reduce entry of Caliciviridae family viruses into intestinal epithelial cells of the subject.
Owner:DST PHARMA INC