The invention discloses a 
laser preparation method of self-cleaning antibacterial glass. Firstly, a prepared 
chemical solution is scoured to the surface of a 
metal substrate, and meanwhile, the bottomsurface of glass covers the 
metal substrate; thirdly, ultrafast 
laser penetrates through the glass to irradiate the 
metal substrate, the glass at the interface is molten, the 
microstructure on the metal is transferred to the glass, meanwhile, the nanoparticles in the solution are reduced and adsorbed to the glass 
microstructure, and then the glass is subjected to annealing treatment, so that a dual-size micro-nano structure covering the non-polar nanoparticles is generated on the surface of the glass. The surface has an excellent self-cleaning super-hydrophobic function, greasy 
dirt and the like on the surface of the glass can be removed by using a small amount of water and labor, almost no water 
stain is left, and the cleaning difficulty in the using process is reduced. Moreover, the super-hydrophobic property can 
resist bacterial adhesion, and the nanoparticles can kill the adhered 
bacteria, so that the surface of the glass has excellent antibacterial / bactericidal functions. The preparation method is simple, has universality and is suitable for glass made of various materials. The prepared glass has the advantages of unchanged mechanical properties and favorable light permeability, and is suitable for large-scale commercial production.