The invention relates to a steam Rankine-organic Rankine combined cycle power generation device, wherein steam in a steam Rankine cycle is cooled by an organic working medium in an organic Rankine cycle, and latent heat of vaporization of the steam in the steam Rankine cycle is recycled to be used for organic Rankine cycle power generation, so that the steam Rankine cycle and the organic Rankine cycle are combined together and an implementable combined recycling device is formed; and meanwhile, the safety difficult problem that waste heat of flue gas is recycled by the organic Rankine cycle is solved, exhaust gas temperature is effectively reduced, and low-temperature corrosion of the flue gas is avoided, and waste gas, waste water and waste heat of waste steam in a steam Rankine cycle system can be effectively recycled. The steam Rankine-organic Rankine combined cycle power generation device can be used for energy-saving reconstruction of existing units, also can be used for designing and constructing new generator units as well, and is especially suitable for new construction, extension and reconstruction of generator units in severe cold areas, water-deficient areas, power shortage areas and the like, so that economic, social and environmental-friendly benefits are remarkable.