The invention relates to an Anari series mongolian
drug intragastric floating sustained release preparation and a preparation method thereof, and belongs to the technical field of manufacturing of drugs. At present, most Anari compounds are
powder, and are easy in
moisture absorption, adhesion and
caking, larger in administration dosage, pungent in
flavor and poor in compliance. The Anari series mongolian
drug intragastric floating sustained release preparation comprises a main
drug and a
pharmaceutic adjuvant, wherein the main drug comprises Anari or extract thereof; a sustained release
adjuvant is used for constructing a skeleton structure of the drug and controlling the dissolving-out speed of the drug; an often release
adjuvant is used for enabling the drug to float and the preparationto be formed; the often release
adjuvant comprises a floating auxiliary and / or a filling agent and / or a binding agent and / or a lubricating agent. By adopting a positioning sustained release dosing
system, the Anari series mongolian drug intragastric floating sustained release preparation is steady and lasting in
drug release and can float sustainably, so that intragastric positioning dosing is achieved, the
bioavailability of
oral administration of the Anari, the defects of the
powder of
large dose and frequent dosing can be overcome, bad
flavor of the drug can be covered, and the complianceof patients is improved. Therefore, a more ideal
treatment effect is achieved.