The invention belongs to the field of assembly of small-caliber bullets, and in particular relates to a screw-in type electric primer explosion-proof screwing machine used in the assembly of small-caliber bullets. A screw-in type electric primer explosion-proof tightening machine of the present invention includes a cartridge cup, a jacking mechanism, a positioning and clamping mechanism, a pit device for automatically pressurizing and searching for a screw-in type electric primer, an air circuit system, a control part and controlling software. The jacking mechanism of the screw-in electric primer explosion-proof screwing machine is installed on the machine base, the cartridge cup is located above the jacking mechanism, and the positioning and clamping mechanism, automatic pressurization and the pit device for finding the screw-in electric primer are located in the cartridge in turn. The top of the cylinder cups are installed on the rack. The air source, valve, air pipe and the pneumatic actuators of the above mechanical parts form an air circuit system. The control software is set in the controller of the control part, and the controller and the control software control the operation of the above-mentioned mechanical structure. The screw-in electric primer explosion-proof tightening machine of the present invention can automatically complete the screwing of the screw-in electric primer, it solves the problem of automatically finding the pit on the screw-in electric primer, and can ensure the precision control of the screw-in electric primer tightening depth , to ensure product quality, realize the separation of man and machine, and ensure the safety of production personnel.