Disclosed is a neodymium-doped lanthanum strontium aluminate tantalate laser crystal and process for preparation, wherein the crystal has a structural formula of (NdxLa(0.3-x)Sr0.7)(Al0.65Ta0.35)O3, wherein the value range of x is between 0.1-10 at%, the preparation method of the crystal comprises the following steps: (1) weighing raw materials of La2O3, SrCO3, Al2O3, Ta205 and Nd203 according to the molecular formula and chemical measurement, (2) mixing the raw material homogeneously, tabletting and placing aluminium oxide crucible into a Muffle furnace, sintering more than ten hours at 1200 deg C, (3) loading the sintered Nd:(La,Sr)(Al,Ta)O3 into a iraurite crucible, using (La,Sr)(Al,Ta)O3 single crystal as seed crystal, growing with intermediate frequency induction Czochralski method in inert gas atmosphere.