The invention discloses a tailing activation process system based on drying, grinding and selecting integrated intelligent production equipment. The tailing activation process system is characterized by involving tailing intelligent production equipment used for carrying out the following activation processes on tailings, namely drying, grinding, powder selecting treatment, drying, grinding and powder selecting circulation treatment of unselected materials of powder selecting and activation treatment of selected materials, and a tailing comprehensive utilization intelligent production execution system, wherein powder separation treatment comprises magnetic separation and screening which are carried out in sequence. A drying, grinding and separation integrated treatment mode is adopted, and the magnetic separation step and the crushing step are separated and put into the powder separation step, so that the stability of the high quality of products is guaranteed; and an intelligent algorithm is adopted for monitoring and adjusting the tailing activation process in real time and monitoring equipment faults and energy consumption, so that intelligent activation production of the tailings is achieved, the average processing time of field problems is shortened by 25%, and the production plan execution rate is effectively improved by 15%.