The invention relates to a high-precision automatic alignment type multi-position workpiece pinching device, which belongs to the field of pinching devices. The high-precision automatic alignment type multi-position workpiece pinching device comprises a chuck mechanism, a telescoping mechanism, an elevating mechanism, an anti-reverse guide mechanism and a base mechanism, wherein the elevating mechanism and the anti-reverse guide mechanism are arranged on both sides of a guide post in the center, the telescoping mechanism is arranged on the upper end surface of a cross beam of an upper T-shaped frame, a telescoping connecting rod of the chuck mechanism is connected with an inner guide post rod of the telescoping mechanism, and the telescoping mechanism is used for controlling the chuck mechanism to stretch, open and close. According to the high-precision automatic alignment type multi-position workpiece pinching device, the alignment requirement of a workpiece can be automatically realized, and the multifunctional requirements of transposition, clamping, retraction and sending, positioning, high-precision mold closing and the like in multiple positions can be satisfied. When the high-precision automatic alignment type multi-position workpiece pinching device is moved, the ranges of elevation, opening and closing, positioning and stretching are large, and the pinching device can be conveniently adjusted, operated and controlled.