2results about How to "Simple and clear structure" patented technology

The invention discloses a BODIPY dye with an annular structure as well as a preparation method and application thereof, relates to the technical field of medical dyes, and solves the problems of stability of the BODIPY dye in an aqueous medium and safety in a living body. The preparation method comprises the following steps: dissolving a compound A and dicarboxylic acid in anhydrous dichloromethane, adding 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride and a catalyst, carrying out a reaction under the protection of nitrogen, and carrying out silica gel column chromatography purification on a crude product to obtain the BODIPY dye with the cyclic structure. The amphipathy of the cyclic BODIPY formed by ester bonds or ether bonds is increased, so that the cyclic BODIPY forms nanoparticles in an aqueous solution, the BODIPY photosensitizer is delivered in a living body, the stability of the BODIPY photosensitizer in water is enhanced, the in-vivo circulation time is prolonged, the safety of the BODIPY photosensitizer in the living body is improved, and the integration of tumor diagnosis and treatment in the living body can be realized.

This invention relates to an electrolytic cell electrode plate and its manufacturing process, comprising a metal electrode plate and a first sealing ring; the metal electrode plate defines a mutually perpendicular X-plane and a Y-plane; a flow channel and a first annular sealing groove are respectively provided on two end faces parallel to the X-plane; an oxygen inlet and a water outlet are provided on the first end face, communicating with the flow channel on that end face and along the Y-plane direction, and a hydrogen inlet is provided on the second end face, communicating with the flow channel on that end face and along the Y-plane direction; there are two first sealing rings, respectively adapted to the shape and size of the sealing grooves on the first and second end faces, and integrally vulcanized with the metal electrode plate. This invention employs a structure that integrally vulcanizes the sealing ring and the metal electrode plate with the sealing groove, processing two components that originally required high-precision tight splicing into a single unit, reducing the risk of hydrogen leakage from the electrolytic cell while improving the stacking efficiency of the electrolytic cell and enhancing the service life and performance of the PEM electrolytic cell.