43 results about "Implant coating" patented technology

A coating layer, for example PEEK or titanium foil, shields a bone implant surface from wearing interactions with surfaces of bone and/or other implants. The coating prevents shedding particles which are difficult to distinguish from evidence of potentially dangerous conditions, for example, microorganism contamination and/or degenerating tissue. Methods and structures for securing a coating layer are described. Other uses and implementations of coating layers are described.

Implants may be coated with a biocompatible coating to improve the biocompatibiiity of the implant. The biocompatible coating may include a bone growth promoting compound. Such compounds include, but are not limited to, phospholipids, bone morphogenetic proteins, or combinations thereof. The bone growth promoting compound may enhance the rate of bone growth proximate to the implant and the integration of the implant into the surrounding bone.

Polymers of fluorinated monomers and acrylate and alkyl acrylates are disclosed which demonstrate improved performance as coatings for implantable devices. Such coatings may, for example, be used to release a bioactive agent from the medical device. One specific application lies in drug-eluting coatings for stents.

The invention relates to a preparation method of a hydroxyapatite/drug-loaded hydrogel composite coating on the surface of micro-arc titanium oxide. The preparation method comprises the following steps of: soaking a titanium sample subjected to micro-arc oxidation treatment in an alkaline solution, and carrying out hydrothermal treatment to form a hydroxyapatite bioactive coating on the surface of micro-arc titanium oxide; putting an aluminum template into a culture dish, then adding a mixture of a prepolymer of PDMS and a curing agent, and curing to obtain a PDMS template; and mixing a chitosan aqueous solution and a sodium alginate aqueous solution, adding a drug to obtain a drug-loaded hydrogel solution, adding a photoinitiator to the drug-loaded hydrogel solution, dropwise adding to the template, placing a sample on the PDMS template, curing under ultraviolet light, and carrying out freeze drying. According to the method, a composite coating with a porous structure and a nanorod shape is generated through micro-arc oxidation and hydrothermal treatment, and the bonding strength and the biological activity of the implant and bones are improved. The drug-loaded composite hydrogel is loaded on the surface of the micro-arc titanium oxide through the PDMS template, so that the implant coating is endowed with more biological functions.

The invention relates to the field of implant coatings and discloses a preparation method of a hard tissue implant coating material. The bio-coating material with both thermal stability and bioactivity is prepared by a method with lower cost and adopting simple equipment. Carbonic acid and fluorine co-doped hydroxyapatite is prepared in the sequence of dropwise addition of sodium fluoride and sodium phosphate by a hydrothermal method, so that finally prepared particles have high purity, good dispersity, good and controllable crystal form and low production cost.

Processes for the preparation of biomaterials, in particular foams and solid structures, suitable for bone surgery and odontology, bone regeneration, bone defect fillings, stabilizing bone fractures, coating of prostheses or implants, fixing of prostheses or implants, drug delivery systems, and tissue engineering scaffolds, and to the biomaterials obtained thereby. Besides that, this invention, also relates to self-setting calcium phosphate foams which may be obtained by simultaneously mixing and foaming of a powder phase and a liquid phase.

The present invention relates to purified multimeric proteins, comprising PlyCB monomers or functional fragments or variants thereof, which self-assemble into a ring like structure. The present invention also encompasses such multimeric proteins that comprise an integrin-binding sequence. The present invention further discloses contrast reagents, implant coatings, bone implants, and complexes for use in bionanotechnology applications, each of which comprise such multimeric proteins.

A method for forming a coating film of a material for enhancing bioactivity, such as a water-soluble vitamin, on a surface of a dental implant, and a dental implant produced by the method, in order to overcome the limitations in improving osseointegration capability, which result from existing physical surface treatments, such as RBM and SLA surface treatments. The methods enable the SLA-pretreated implant surface to have blood affinity and an enhanced bioactive function, thereby providing a method for producing a dental implant which has excellent biocompatibility and high osseointegration capability after the implant procedure and thus has enhanced bioactivity, and a dental implant produced by the method. The surface of the dental implant, from which organic pollutants have been removed, are coated with a bioactive material, thereby enhancing blood affinity and bioactivity of the implant and thus improving initial osseointegration capability of the implant.

Methods of reducing or preventing an adverse response to an implanted or inserted material in a patient are provided. The methods include the step of treating at least a portion of an external surface of the implanted or inserted material with an effective amount of a birth tissue material coating corn position.

A medical implant structure is provided comprising a substrate 10 with at least a first surface and a second surface that surfaces differ from one another with regard to at least one property in relation to biological material.

The present invention relates to methods for producing fibrous fibrinogen biomaterials that can be used as three-dimensional scaffolds. The methods of this invention enable the controlled detachment of fibrous fibrinogen scaffolds in vitro. The fibrous fibrinogen biomaterials generated by the methods of this invention can be detached in a solution. Alternatively, the fibrous fibrinogen scaffolds of this invention can be immobilized on a surface. The fibrous fibrinogen biomaterial can be used in medicine, such as in wound healing, regenerative medicine, dermal reconstruction, skin repair, bone vessel repair, blood vessel regeneration, tissue engineering, and implant coatings. The biomaterials can be generated “on-demand” and can be transferred to a site of injury, such as to a wound.

The invention discloses a medical antibacterial coating layer and a preparation method thereof, and belongs to the technical field of medical antibacterial materials. A method of preparing an HA (hydroxyapatite) coating layer comprises the following steps: mechanically grinding HA+AgNO3 and HA+norfloxacin according to a ratio of 4 to 1, pressing the material into a target with a diameter of 30 mmand a thickness of 5 mm on the premise of uniform mixing, putting the target into a pulse laser radiation vacuum cavity, and selecting quartz, a silicon wafer and a copper gauze to form a substrate; carrying out deposition by taking YAG:Nd<3+> as a laser source, thus obtaining a thin film sample. The HA with high biocompatibility is used as an implant coating layer material widely applied to plastic surgery, neurosurgery and dentistry; an HA thin film prepared by using a pulse laser deposition technology has a high degree of crystallinity and high bonding strength. The HA antibacterial coatinglayer obtained through the preparation method stabilizes antibiotic and silver particles on the surface of and in the film, so that the antibiotic and silver particles can fully exert an antibacterial effect.

Disclosed herein is a material that may be useful as a coating for optical slides and medical implants. The material may aid or restrict grown of cells on a coating of the composite material. As such, there is provided a composite material having a substrate on the surface of which a coating layer of an amorphous metal oxide is formed. The metal oxide may be one or more of Ag₂O, ZnO, ZrO₂, TiO₂, CuO, and Y₂O₃ and the coating layer may be from 5 to 100 nm thick and have a root mean square roughness of the coating surface is from 0.1 to 0.7 nm.

The present invention provides polymer brush constructs, for example, surfaces decorated with hyaluronan polymers, and methods of making the same. The constructs are useful as functional materials for numerous applications, e.g., as lubricants, implant coatings, bandages and other uses.

Disclosed is a method for producing an implant coating that has a defined toxicity. The method is characterized by the following steps: i. a sol is produced from a biotoxic solution containing precious metal ions and a precursor solution for a titanium oxide; ii. an implant is coated by applying the sol in a sol-gel process; iii. the coating is pyrolyzed and sintered without admitting any light, the precious metal ion concentration in the dried coating ranging from 10 to 60 percent relative to the total weight of the dried coating; and iv. at least subareas of the coating produced without admitting any light are illuminated in order to reduce the toxicity of the dried coating to a predetermined measure.