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2 results about "Polypyridine complex" patented technology
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Polypyridine complexes are coordination complexes containing polypyridine ligands, such as 2,2'-bipyridine, 1,10-phenanthroline, or 2,2';6'2"-terpyridine. Polypyridines are multidentate ligands that confer characteristic properties to the metal complexes that they form. Some complexes strongly absorb light via a process called metal-to-ligand charge transfer (MLCT). The properties of these complexes can be tuned by changes in substituents. For example, electron donation, electron withdrawal, and π-conjugating groups, to the polypyridine moiety. The MLCT absorption band can be shifted, the emission wavelength can be changed, and the emission lifetime can be extended.
Near-infrared luminous ruthenium (II) complex, preparation method thereof and application of complex as DNA intercalator
The invention relates to the technical field of DNA intercalating agents, in particular to a near-infrared luminous ruthenium (II) complex, a preparation method thereof and application of the complex as a DNA intercalating agent. The preparation method comprises the following steps: firstly, preparing a precursor 4 '-(1H-benzimidazole-2-yl)-2, 2': 6 ', 2' '-terpyridyl; then, preparing a target precursor, namely, 2-(4-(anthracene-10-yl)-6-(pyrazine-2-yl) pyridine-2-yl) pyrazine as a ligand; and finally, synthesizing a complex [Ru (An-di (2-Pz) Py) (Bitpy)]. The complex is inserted into a DNA base pair as an intercalating agent, has very strong interaction with DNA, and provides basic research for researching the interaction mode of the ruthenium (II) polypyridine complex of the tridentate ligand and DNA and taking the ruthenium (II) polypyridine complex as a diagnosis and treatment reagent.
Owner:GUANGXI NORMAL UNIV FOR NATITIES
A pyrrole-modified iridium polypyridine complex for antibacterial purposes, its preparation method and application.
This invention belongs to the field of antibacterial pharmaceutical technology, and discloses a pyrrole-modified iridium polypyridine complex for antibacterial purposes, its preparation method, and its applications. In the compound structure of the pyrrole-modified iridium polypyridine complex, pyrrole is a penta-nitrogen heterocycle with significant research value. Combined with the metallic element iridium, compared to traditional small organic molecules, it enhances its ability to penetrate bacterial cell membranes, improves transmembrane activity, and effectively penetrates into the bacterial cell membrane, generating ROS-induced oxidative stress, thereby leading to bacterial death. Experiments have demonstrated that the complex of this invention can produce ROS-induced oxidative stress and inhibit biofilm formation.
Owner:JIANGXI SCI & TECH NORMAL UNIV