The invention relates to a high-gain hybrid photomultiplier based on a micro-channel plate. An MCP (micro-channel plate) is placed behind a photocathode to amplify photoelectrons generated by the photocathode, and the amplified electrons are accelerated under an external voltage, and the motion trail is restrained by the focusing electrode to ensure that high-energy electrons can bombard a wide bandgap semiconductor detector. A 6,000-20,000V negative high voltage can be loaded to the photocathode, and the voltage of the photocathode, the voltage of the MCP and the voltage of a focusing electrode can be flexibly adjusted through the ratio of three voltage dividing resistors in a voltage dividing circuit according to needs, thereby achieving the adjustment of the gain and time characteristics. The gain of the hybrid photomultiplier is not only limited to high gain, but also can be adjusted within a wide gain range (102-106) through the existence of the MCP or the multi-stage MCP, an external voltage value and a wide bandgap semiconductor detector structure, and different gain requirements can be met.