The invention relates to the technical field of ventilation cabinet illumination lamps, in particular to a laboratory ventilation cabinet LED illumination lamp set. The illumination lamp set comprisesa background lamp, a front pillar lamp, a top lamp and a power supply system, wherein an intelligent switch is arranged between the front pillar lamp and the power supply system, an intelligent switch is arranged between the top lamp and the power supply system, infrared transmitters are arranged at two sides of the lower end of a ventilation cabinet body, infrared receivers are arranged at two sides of the lower end of a sliding door, and the intelligent switches, the infrared transmitters and the infrared receivers are electrically connected with a single-chip microcomputer respectively. According to the illumination lamp set, when the infrared receivers receive signals sent by the infrared transmitters, the single-chip microcomputer receives the signals sent by the infrared receivers and controls the corresponding induction switches to turn off the front pillar lamp and the top lamp; in an experiment state, the illumination lamp set cannot perform perpendicular incidence towards the outer side of the cabinet body, so that both eyes of an experimenter are effectively protected, and the situation that light pollution influences observation of an experiment process by the experimenter is avoided; and in a non-experimenter state, only the background lamp in the illumination lamp set works, so that energy is saved.