The invention provides a high-clearance intertillage, weeding and fertilization machine. Middle-and-later-period operation of field high crops can be achieved through traction of a high-clearance tractor. The machine comprises a traction frame and a plurality of sets of weeding, ditching, fertilizing and soil covering devices, and the traction frame is connected with the weeding, ditching, fertilizing and soil covering devices through a four-rod floating part; the weeding, ditching, fertilizing and soil covering devices comprise mounting frames, weeding components, ditching and fertilizing parts, intertillage soil covering parts and land wheel profiling parts which are sequentially installed on the mounting frames. On the basis of the high-clearance intertillage, weeding and fertilizationmachine, the traction frame comprises a portal frame, walking wheels and one or more adjustable connecting frame; the walking wheels are arranged on vertical frames on two sides of the portal frame; the adjustable connecting frames are fixed to a cross beam of the portal frame through U-shaped bolts, and the difference of the number N of the weeding, ditching, fertilizing and soil covering devicesand the number M of the adjustable connecting frames is 2.