The invention discloses the specificity marker
protein TS / MEDP
antibody preparation and the purpose. The
molecular biology technology is utilized, and a new
gene is cloned in a
stomach cancer cell and is named as TS / MDEP. A polyclonal
antibody for preventing the TS / MDEP is prepared, and a high specificity
antibody is acquired through the antibody purification technology. The expression characteristics of the TS / MDEP
gene in a tumor
cell line and a tumor
cell tissue are verified from the mRNA and
protein level, the expression in 14 tumor cell lines including the tumor cell line is determined, the dependance of
cell cycle is assumed, the excess expression exists in
stomach cancer,
breast cancer and
cervical cancer tissues, no expression is in the corresponding normal tissues, and the expression exists in an
embryo tissue. The high expression of the TS / MDEP in the
embryo tissue with exuberant cell proliferation is validated, after growing up, the
gene is closed, and the high expression exists in the
tumor cells. The TS / MDEP has the seasonal specificity expression to clew the occurrence and the development of the
cell cycle control abnormity caused by the high expression of the TS / MDEP. The obtained antibody for preventing the TS / MDEP can be used to monitor the
cell cycle advancement and the clinical biological behavior of the gastroenteric tumor.