78 results about "High intensity focused" patented technology

The invention provides a phased array high-intensity focused ultrasonic therapy system which comprises an ultrasonic transmitting device, a signal processing device, a feedback device and a human-computer interaction device. The ultrasonic transmitting device is respectively connected with the signal processing device and the feedback device, and the feedback device is respectively connected with the signal processing device and the human-computer interaction device. The feedback device of the phased array high-intensity focused ultrasonic therapy system can output intensity instructions and frequency instructions to the ultrasonic transmitting device according to a target tissue three-dimensional image, a non-target tissue three-dimensional image and a tissue variable quantity outputted by the signal processing device and a preset tissue variable quantity to control the intensity and the frequency of ultrasonic waves transmitted by the ultrasonic transmitting device to adapt to the intensity needed by therapy or detection, so that target tissues can be damaged, and non-target tissues cannot be damaged in the therapy process.

The invention relates to a multi-channel high precision phase control signal generation device which utilizes a programmable read-only memory to generate a customized special circuit in an FPGA (Filed Programmable Gate Array) circuit through a VHDL (Very High Speed Integrated Circuit Hardware Description Language) language programming. The multi-channel high precision phase control signal generation device comprises a phase shift module, a phase coding module, an address coding module and a plurality of multi-channel gates. By taking a high precision active crystal oscillator as an information source, all multi-channel gates works in parallel to receive phase control signals of a host computer and output square wave signals of a multi-channel special phase. The output square wave signals access resonance of a power amplifier to generate sine wave signals with the same frequency and phase with the traditional output signals and the sine wave signals are used for excitation signals of an ultrasonic transducer array element in a phase control type high intensity focusing ultrasonic treatment system; and the frequency of the crystal oscillator is determined by the resonance frequency and the phase control precision requirements of the ultrasonic transducer array element. The invention dramatically increases the channel amount of the phase control signals and enhances the precision of the phase control signals, thereby satisfying the needs of the high intensity focusing ultrasonic treatment system.

The invention relates to a piezoelectric focusing ultrasonic transducer, which comprises a concave spherical lightening housing (1), a unit focusing energy converter (2), an end cap (3), a gasket (4), a connector base (5) and an insulating connector base (6). The method uses the polyvalent secondary focusing method to geometrical focus with high intensity. The device can produce the high-intensity focusing ultrasonic with prompt high pressure and temperature effect, and has small focus range and large acoustic pressure, and the system is stable, and it can be widely used in the biology, medical treatment, manufacturing and other technique fields.

The invention relates to a measuring system of a high-intensity focusing ultrasonic sound field. The measuring system comprises an intelligent data processing module, a multi-degree of freedom progressive scanning control module, a data acquisition module and a hydrophone, wherein the intelligent data processing module sends a command to the multi-degree of freedom progressive scanning control module to perform intelligent sound field scanning, and acquires corresponding sound field distribution and sound field parameters according to acquired data; the data acquisition module acquires voltage signals sensed by the hydrophone; the multi-degree of freedom progressive scanning control module consists of a three-dimensional step motor controller, a three-dimensional motion device and a hydrophone fixing device; and a sound-absorbing rubber is adhered to the bottom surface of the hydrophone fixing device. The three-dimensional motion device performs the motion modes of inching, increment or synchronous increment and the like according to the command of the three-dimensional step motor controller; and the three-dimensional step motor controller controls multi-shaft simultaneous motion, single-shaft uniform motion or single-shaft variable motion according to the command of the intelligent data processing module. The measuring system can realize quick, accurate, intelligent and graphical ultrasonic sound field measurement.

A system, method and devices for providing improved methods to harden UV-curable coating materials when those coating materials are applied over optical fibers or other optical targets during the manufacturing process is provided. The technology disclosed herein uses LEDs (or low power light bulbs) to create UV power, which is focused with high intensity on the surface of a coated fiber. This is done simultaneously from multiple angles to fully cover the target product over 360 degrees of surface and is then repeated a number of times along the product path to ensure sufficient degree of curing.

A nontracking solar concentrator, called the wedge, is given the ability to collect overhead light. This is made possible by a new prism, having the cross section of a cornucopia, that delivers an abundance of bright light into the wedge to create a higher intensity focus.

The invention is a kind of transverter array in high-intensity focusing supersonic tumour treat. The invention is made up of matching layer and piezoelectricity chinaware pieces. The matching layer is a even bowl sound radiating layer, all the piezoelectricity chinaware pieces are stuck on the outer surface of the same matching layer, the piezoelectricity forms the transverter array. The invention has a high focusing sound-intensity ratio and sound speaking feature; the cost is low; the structure is simple, and the stability and the reliability are enhanced.

An equipment for measuring the sound field in a focused region of high-intensity focused ultrasonic field is composed of a supporting frame, a sound-absorbing water tank, a data processor, a pressure-sensitive sensor able to directly measure the sound pressure of high-power high-intensity sound field, 3D movement regulator, 2D rotation regulator, and probe holder. Its advantages are high speed and accuracy and simple operation.

The present invention pertains to the biomedical field, more particularly, the present invention relates to a sound-sensitive agent which has the oxygen carrying function. The sound-sensitive agent is a composition which is composed of the substances with the oxygen carrying function and the sound-sensitive substances. The present invention makes use of the substances with the oxygen carrying function to improve the oxygen content of the target area, strengthen the sonodynamic effect of the sound-sensitive substances and develop the safe and effective sound-sensitive agent. The sound-sensitive agent which has the oxygen carrying function can be used as the sound-sensitive agent during the sonodynamic treatment process and can be used as the synergistic agent during the low-intensity/ high-intensity focused/ non-focused ultrasound treatment process, so the present invention is applicable to the skin care, obesity, benign and malignant proliferative diseases.

A 3-D locating system for high-intensity focused ultrasonic operation is composed of a 3-D moving bed fixed on the floor, a machine frame arranged at outside of longitudinal central line of the said bed, a C-shaped arm mechanism on the machine frame, and a treating head assemblage containing a set of precise location system and ultrasonography-B imaging mechanism so as to realize functions of monitoring and regulating real-time location while treating.

A locating and scanning device of focused ultrasound treatment with high intensity is a three-dimensional locating, five-dimensional accurate scanning device in a focused ultrasound treatment system with high intensity. A ultrasonic probe for finding position and a focused ultrasonic transducer are mounted on a bracket of five-dimensional accurate scanning device in treatment head in way of internal and external shaft sleeving. The treatment head is connected with an arm plate by revolving modules of the two sides and a set of pushpull modules and the arm plate is connected with a connecting plate by revolving shaft and arc track and the connecting plate is connected with an upright column by a straight guiderail, finally the three-dimensional locating device is obtained. The focused ultrasound treatment system with high intensity focuses the ultrasonic transducer to implement the upper to lower treatment mode. After three-dimensional locating, the system exactly locates, scanns, images and treats the focus of patient by the five-dimensional accurate scanning kinematic mechanism in the treatment head. The focused ultrasonic transducer can satisfy the different treatment attitudes from upper to lower and reduce the movement error during accurate scanning.

The invention relates to a layer stripping method in a chip failure analysis process, comprising the following steps: (1) providing a chip, the chip has a multi-layer structure, and includes at least one target analysis layer, and the target analysis layer includes a layer to be analyzed area; (2) using ion beams to carry out peeling treatment from the surface of the chip, remove one or more layers above the target analysis layer, and expose the area to be analyzed, wherein the ion The beam includes at least one broad ion beam with a beam spot diameter not less than 1 mm. In this peeling method, the ion beam formed by at least one wide-beam ion beam can be used to obtain a relatively uniform peeling surface, which avoids a single beam of high-energy focused ion beam directly hitting the surface of the chip, causing damage to the target analysis area. The precision of peeling is effectively improved, and the processing range is expanded at the same time, and the peeling efficiency is high.

The invention discloses a method for reducing the temperature error in magnetic resonance temperature imaging, which is used for the high-intensity focused ultrasound HIFU treatment monitored by magnetic resonance, the method comprises that: a reference image which is generated on two or more positions by an HIFU treatment head is carried out the interpolation, thus obtaining the reference image of the moving position of the HIFU treatment head; and the temperature change of a heating region is calculated according to a phase diagram of the interpolated reference image of the moving position of the HIFU treatment head and a heating image which is generated at the position by the HIFU treatment head. The invention further discloses a device for reducing the temperature error in the magnetic resonance temperature imaging, which comprises a reference image interpolation unit and a temperature calculation unit. The usage of the method and the device of the invention can significantly reduce the temperature error which is caused by the change of the magnetic susceptibility during the movement of the HIFU treatment head, which can not only obtain the accurate temperature change of the heating region, but also can reduce the complexity of the operation and the treatment time of the HIFU treatment.

The invention relates to a preparation method and applications of a mesoporous calcium carbonate medicinal composition modified by hyaluronic acid, for effectively simultaneously realizing targeting, controlled release and ultrasonic therapy and ultrasonic imaging combination, and further realizing diagnosis and treatment integration on cancer. The technical scheme is as follows: the preparation method comprises the following steps: modifying hyaluronic acid on aminated calcium carbonate obtained by reacting mesoporous calcium carbonate and 3-aminopropyl triethoxysilane, and then loading a micromolecular sonosensitizer, thus obtaining the mesoporous calcium carbonate medicinal composition modified by hyaluronic acid. The preparation method has the advantages that a preparation process is simple, a method is stable and reliable, the production cost is low, and the prepared mesoporous calcium carbonate modified by hyaluronic acid and the medicinal composition of mesoporous calcium carbonate simultaneously have the efficacies of tumor targeting, in vitro and in vivo double-stimulation (in acid environment and under high-intensity focused ultrasonic condition) sensitive medicine release, sonodynamic therapy and ultrasonic imaging combined diagnosis and treatment integration, belong to an innovation in tumor treatment medicines, and have enormous economic and social benefits.

The invention discloses a novel optical fiber fabry-perot ultrasonic hydrophone and a manufacturing method thereof. The hydrophone can be used for measuring the high-intensity focusing acoustic field, and comprises optical fiber and a quartz capillary fused and spliced at the end part of the optical fiber; a high-reflective film is respectively plated at the end surface of the quartz capillary and the end surface of the optical fiber right against the quartz capillary; the outer diameter of the quartz capillary is identical to the outer diameter of single-mode optical fiber, and the inner diameter of the quartz capillary is smaller than the fiber core diameter of the single-mode optical fiber; if the inner diameter of the used quartz capillary is greater than the fiber core diameter of the optical fiber, the fusion splicing intensity can be properly enhanced, so that the front end of the quartz capillary is collapsed until the inner diameter of the quartz capillary is smaller than the fiber core diameter of the optical fiber. The novel optical fiber fabry-perot ultrasonic hydrophone has the advantages of simple structure, high interference signal, high intensity, high spatial resolution, high sensitivity and the like, and can bear high temperature and high sound pressure of an HIFU (high intensity focused ultrasound) sound field.

A medical apparatus (300, 400, 500) comprises a high intensity focused ultrasound system (322) configured for for sonicating a target volume (340) of a subject (318). The medical apparatus further comprises a magnetic resonance imaging system (302) for acquiring magnetic resonance data (356, 358, 360, 368, 374) from an imaging zone (308). The treatment volume is within the imaging zone. The medical apparatus further comprises a memory (352) containing machine executable,a control module (382, 402) for controlling the sonication of the target volume using the magnetic resonance data as a control parameter, and a processor (346). Execution of the instructions causes the processor to repeatedly acquire (102, 202) magnetic resonance data in real time using the magnetic resonance imaging system and control (104, 206) sonication of the target volume by the high intensity focused ultra-sound system in real time using the sonication control module and the magnetic resonance data.

In a method and magnetic resonance (MR apparatus for reducing aliasing artifacts in the imaging for MR-monitored high intensity focused ultrasound HIFU therapy, a primary coil is used to receive the MR signals, and an additional coil is provided to receive interfering MR signals that form aliasing artifacts in the MR-monitored HIFU therapy imaging. The MR signals received by the primary coil and the interfering MR signals received by the additional coil are concurrently acquired. The interfering MR signals received by the additional coil are removed from the MR signals received by the primary coil. MR images are generated based on the MR signals with the interfering MR signals removed. Aliasing artifacts caused by the interfering MR signals thus are removed from the MR images without reducing the resolution of the scanned body parts in the MR images. In addition, the MR scanning time can be maintained by using a proper phase oversampling technology in the concurrent signal acquisition.

An image monitor used in high-intensity focused ultrasonic therapy for real-time monitor to the injury of skin and hypoderm is composed of an imaging unit for taking the images of skin and hypoderm, an image acquiring unit for acquiring the data about said images, an analyzing and processing unit for storing said image data, comparing the data before treating with the data uring treating, and analyzing the injury, and a result display unit. Its method is also disclosed.

A device for thermal keratoplasty, the device comprising a plurality of ultrasonic transducers for emitting ultrasound waves, wherein the ultrasound waves of at least one of the transducers is focused on a corresponding area of the cornea in order to heat these area and cause collagen shrinkage and at least one of the transducers is capable of receiving ultrasound waves for ocular imaging.

A method for automatically selecting a region of interest covering a heated area, in the context of high intensity focused ultrasonic technology achieves automatic selection of the region of interest on the basis of the phase recognition completed in a magnetic resonance data acquisition and the position of the focus of a focused ultrasonic sensor. The method includes the steps of acquiring the phase data of a scanned area during a scanning process, then determining a heated area in the scanned area according to the phase data acquired; and in a displayed image acquired by the image reconstruction, demarcating a region of interest covering the heated area according to a predetermined size of said region of interest that covers and is larger than the heated area. The method causes the heated area to be automatically and completely included in the region of interest; and eliminates the instability of a manual selection of the region of interest, and the selection efficiency and accuracy of the region of interest are improved, so as to provide a basis for automatically achieving parameter-free selection.