30 results about "PLLA polymer" patented technology

Environmentally degradable films comprising a blend of polyhydroxyalkanoate copolymer and a polylactic acid polymer or copolymer are disclosed. Laminates having a first layer comprising a PHA copolymer and a second layer comprising a PLA polymer or copolymer are also disclosed. Disposable articles comprising the environmentally degradable films or laminates are also disclosed.

The invention provides a biodegradable injectable filler as well as a preparation method and application thereof, particularly provides an injectable implant composition and a preparation method thereof. The composition contains biodegradable polymer particles and hyaluronic acid with the content not higher than 0.1%. The hyaluronic acid can significantly improve the hydrophobic property of the surface of a PLLA polymer scaffold, promote adhesion and growth of collagen cells on the surface of the PLLA polymer scaffold, significantly improve a filling effect or a fulling effect of the composition, remove wrinkles, enhance attractiveness of facial skin, improve the suspension stability of the PLLA particles after freeze-drying redissolution, reduce hydrolysis and degradation of PLLA ester bonds, and reduce adverse reactions such as swelling, inflammation and allergic reaction possibly caused by acid degradation products.

The invention discloses a polylactic acid elastic non-woven material beneficial to tissue regeneration and a preparation method thereof. The nano-micron polylactic acid elastic non-woven material is of an integrated structure composed of polylactic acid nano-micron fibers serving as a main body and polyolefin elastic filaments serving as a framework. The preparation method comprises the followingsteps of carrying out in-situ spray molding on a modified polylactic acid polymer and a polyolefin elastic framework to obtain a laminated fiber web, and carrying out water jet composite processing onthe laminated fiber web to form an integrated structure, and carrying out single-side lustring on the fiber net with the integrated structure to obtain a nano-micron elastic light patch and the preparation method thereof. The non-woven material prepared by adopting the method has an integrated structure, is not layered, has a relatively good anti-adhesion effect, also has excellent elasticity andflexibility, and can be applied to multiple fields of hernia patches, medical dressings, medical bandages and the like. The preparation method of the non-woven patch has the characteristics of shortprocess flow, high production speed and low cost, and is suitable for large-scale industrial production.

The invention relates to a polylactic polymer with organic phosphate bond in the main chain of biological degradation, which can change into innocuity residue by internal degradation. The solidity and hydrophobicity of lactic acid or glycollic acid prepolymer are strengthened by adding a circularity compound that potentially improves the final polymer Tg containing phosphorus, redudeces the need of high molecular weight prepolymer, and the internal degradation time is quickened by using low molecular weight preolymer and improving organic phosphate contents, which improves the encapsulating ratio between polymer and a plurality of aquosity medicines (such as paclixtel or docetaxel). Finally, practical matrices formed by medicine and polymer have much better mixing compatibleness without phenomena of medical phasic demixing and independent crystallization.

The invention discloses a modified polylactic acid material as well as a preparation method and application thereof. The modified polylactic acid material comprises polylactic acid, a polymer and a block polymer, wherein the mass ratio of the polylactic acid to the full-degradable polymer to the block polymer is (0.3-0.7): (0.2-0.5): (0.03-0.1). The modified polylactic acid material can effectively solve the problem that an existing polylactic acid material is poor in compatibility, degradability and mechanical property.

The invention discloses a fast-crystallization and high-crystallinity polylactic acid modification method which comprises the following steps: 1, performing melting extrusion on carbon fiber, L-polylactic acid, D-polylactic acid, polyglycolic acid and starch through a twin screw extruder so as to obtain a nucleating agent; 2, in parts by weight, putting semi-crystalline polylactic acid, a polymertype crystal accelerator, the nucleating agent and a plasticizer into a container according to a ratio, adding a dichloromethane solvent, performing stirring with a magnetic stirrer, and performing volatilization at room temperature to remove the solvent so as to obtain a lactic acid premix; and 3, melting and blending the polylactic acid premix with polyvinylidine according to a ratio, so as to obtain a polylactic acid complex. The method has the beneficial effects that a molding process is improved, the polymer type crystal accelerator is added to reduce activation energy required for formation of lattice of polylactic acid, the difficulty of crystallization can be reduced, and the crystallization rate can be increased.

A bioplastic blend is disclosed. The bioplastic blend may comprise a polylactic acid polymer and a lignocellulosic biomass. The lignocellulosic biomass may be a particulate and have an average particle size that is less than or equal to 60 micrometers, or less than or equal to 50 micrometers. The lignocellulosic biomass may be a particulate and comprise greater than or equal to 50 percent by weight of the bioplastic blend, or greater than or equal to 60 percent by weight of the bioplastic blend. In addition, the bioplastic blend may comprise a plasticizer.

The invention discloses a novel bionic 3D printing bioactive fusion cage and a preparation method thereof. The preparation method of the fusion cage comprises the following steps: (1) preparing a 1,4-dioxane solution of PLLA polymer; (2) mixing n-HA with the PLLA polymer solution to obtain a basic solution; (3) 3D-printing a porous anatomical fusion cage, and removing organic solvent to obtain a porous anatomical fusion cage; (4) preparing loading PLGA/ rhBMP-2 nanoparticles; (5) dissolving the PLGA/ rhBMP-2 nanoparticles in 10ml of distilled water; (6) soaking the porous anatomic fusion cagein the PLGA/ rhBMP-2 nanoparticle solution, and coating meshes of the porous anatomic fusion cage with the PLGA/ rhBMP-2 nanoparticles; and (7) freeze-drying and forming the porous anatomical fusion cage. The novel fusion cage prepared by the method with three-dimensional physiological anatomical space conformation, controllable degradation and controlled release realizes the optimization of mechanical property, has controllable degradation and bone function promotion, and solves the problems of fracture and collapse of OLIF operation endplate and displacement of a fusion cage.

The present invention provides a biodegradable polymer composition having an elongation-at-break of at least 200 percent comprising a polylactic acid-based polymer and a mechanical performance modifier, wherein addition of the mechanical performance modifier to the biodegradable polymer increases the elongation-at-break to at least 200 percent while retaining at least 75 percent of the tensile strength of unmodified polylactic acid polymer and wherein the melting temperature of the biodegradable polymer is within 5 degrees Celsius of the melting temperature of unmodified polylactic acid polymer. In one embodiment, the mechanical performance modifier is poly(ethylene glycol) sorbitol hexaoleate. In another embodiment, the mechanical performance modifier is polycaprolactone.

The invention belongs to the technical field of bioengineering carrier materials, and particularly discloses a method for producing a porous three-dimensional material through enzymatic degradation ofa PCL/PLLA polymer. The method comprises the following steps of dissolving PCL and PLLA in a mixed solvent of dichloromethane and N,N-dimethylformamide to obtain a PCL/PLLA solution; carrying out electrostatic spinning on the solution to obtain a PCL/PLLA fibrous membrane; and placing the fibrous membrane in a PBS buffer solution added with esterase to be degraded, so that the porous three-dimensional PCL/PLLA fibrous membrane with the mechanical property not obviously reduced is obtained. The porous three-dimensional PCL/PLLA fibrous membrane is expected to serve as a high-quality raw material for preparing a porous tissue engineering scaffold or water/air treatment. According to the method, by adjusting the concentration and degradation time of the esterase, the purpose of controlling the size and number of micropores in the surface of the PCL/PLLA fibrous membrane can be achieved, and a new thought is provided for preparing porous materials with high porosity.

The notched Izod impact toughness and tensile elongation of poly(lactic acid) (PLA)-homopolymers are increased by about 2 to about 4 times by blending therewith a PLA-copolymer having a difunctional flexible middle segment such as a polysiloxane or a polyether from about 0.6 wt. % to about 20 wt. %. The PLA-homopolymer-PLA-copolymer blend having a difunctional flexible polymer from about 0.5 wt. % to about 10 wt. % is thermally annealed to provide impact toughness of at least about 5 kJ/m² and tensile elongation of greater than 12%. This exceptional improvement observed in the PLA blend is a synergistic effect of the addition of the difunctional flexible polymer of the copolymer and thermal annealing. The improvement observed in the mechanical properties with high PLA homopolymer content above about 90 to about 98 wt. % is unusual and results in an increased scope of molding and thermoforming applications. The annealed PLA-copolymers having a difunctional flexible middle segment have also been found to have improved notched Izod impact properties.

An amorphous polylactic acid polymer having a weight average molecular weight in the range of about 35,000 to 180,000 is described. The polylactic acid polymer composition can be hammer milled without cryogenics result in the form of particles wherein 90% of the particles have particle size of about 250 μm or less and the material has a glass transition temperature of between about 55° C. to about 58° C. and a relative viscosity of about 1.45 to about 1.95 centipoise.

The invention discloses a heat-resistant polylactic acid polymer, which comprises the following components in percentage by mass: 0.1-1.0% of poly L lactic acid and poly D lactic acid blended resin, 50-95% of base material resin, 1-50% of a degradation material, 10-90% of amorphous polylactic acid and trace amounts of polycaprolactone and polyhydroxyalkenone.

The present disclosure relates to a degradable extruded web comprising a plurality of interconnected strands, at least a portion of the strands being made from a polymer blend comprising a polylactic acid polymer composition, a polybutylene succinate, and a degradation additive comprising a degradation agent in a carrier resin. The present disclosure also relates to turf and methods of making turf using such degradable extrusion webs.