The invention discloses a quality control material and a calibration material for verifying hematology analyzer. Various liquids are integrated; a cell treating liquid integrates the functions of anti-coagulation, blood cell preservation and cell solidification stabilization; secondly, a manufacturing process is optimized, and pre-treatment is carried out immediately once blood is sampled, so that on one hand, the blood is prevented from coagulation and hemolysis, and on the other hand the immobilization of the blood cells is ultimately realized, and at the same time the activity of fresh blood is not lost; and by utilizing the process, not only the freshness of the blood cells is determined, but also the aging of the blood cells alive is determined, subsequently, by utilizing a centrifugation and separation technique, expected blood cells are extracted, and finally cell simulants of different concentrations are added so as to synthesize a complete standard substance; such process is low in production cost, the produced calibration material and the quality control material are high in yield; and the synthesized calibration material and the quality control material are stable in activity and longer in aging.