211results about How to "Effective aggregation" patented technology

The invention discloses a pH-responsive polyethylene glycol-anticarcinogen conjugate, and a synthetic method and application thereof. After anticarcinogen molecules and polyethylene glycol are covalently linked through pH-sensitive phenylimide linkage, the conjugate is formed, wherein, anticarcinogen can be doxorubicin, epirubicin, daunorubicin, demethoxydaunorubicin or hydrochlorides of the above-mentioned anticarcinogens. The phenylimide linkage is stable under the condition of a normal physiological pH value but undergoes hydrolysis under the condition of a slightly acidic pH value, e.g., a solid tumor cell external pH value and a cell endosome and lysosome pH value; that is, the phenylimide linkage is sensitive to changes of pH values in a range of 7.4 to 4.5 or to below 4.5. The polyethylene glycol-anticarcinogen conjugate has amphiphilic nature and can form nanometer-scale micelle in a saline solution through self-assembly; the micelle can be used as a drug carrier to carry hydrophobic drugs and form a nanometer micelle preparation cladded with drugs, thereby realizing synergy therapy of a plurality of drugs.

Water-cooling arrangement includes stator cage and cooling water channel. Cooling water channel in stator cage is arranged in axial direction inside stator cage in not helical round about manner. The cooling water channel can be as single circuitous water channel, or a combination formed from multiple circuitous water channels. Each pair of water channel possesses a cooling water outlet and a cooling water inlet. The cooling water outlet and a cooling water inlet can be arranged at axial same side of stator cage, or arranged at different sides. Water outlets and water inlets of multiple water channels can be arranged in same direction or in reversal directions. Circuitous water channels are in reversal directions can reduce temperature gradient at different parts of the stator cage further.

Solar heating is an environment-friendly and effective means for reducing building energy consumption which is increased day by day and enabling a city and a village to enjoy the same heating comfort, but an existing heat collecting way is large in heat collecting area, low in heat transfer efficiency and low in building integration flexibility. The invention provides a novel solar building heating, heat collecting and transmitting system without mechanical work consumption. The solar building heating, heat collecting and transmitting system mainly consists of a composite paraboloid light condensation heat collector, a loop-circuit heat pipe and a user hot water system, wherein the loop-circuit heat pipe is formed by connecting multiple evaporators in parallel. According to the solar building heating, heat collecting and transmitting system provided by the invention, the composite paraboloid light condensation heat collector is adopted, and efficient collecting of solar energy is realized through pure light condensation; efficient collecting of heat is realized through the multiple evaporators of the loop-circuit heat pipe which are connected in parallel; solar heat driving without the mechanical work consumption is realized by utilizing capillary suction forces of capillary cores of the multiple evaporators of the loop-circuit heat pipe; efficient, long-distance and multi-angle transmission of high-load solar heat energy is realized by utilizing the circulation phase change of a working medium in a closed space, and thus efficient collection and transmission of low-temperature solar energy are realized.

The invention relates to a process for comprehensively recycling copper and iron through ore phase restructuring of copper smelting molten slag. The process comprises the following steps of 1, molten slag ore phase restructuring, wherein when the copper smelting slag is in the molten state, a composite additive accounting for 8-20% of the mass of the copper slag is added, then gradual cooling treatment is conducted, and the composite additive is composed of 40-50% of quick lime, 10-15% of manganous oxide, 10-15% of pyrite, 5-15% of chalcopyrite and 10-20% of an iron oxide; 2, flotation, wherein after modified slag obtained in step 1 is subjected to crushing and ore grinding, floatation treatment is conducted; and 3, magnetic separation, wherein tailings obtained through flotation conducted in step 2 are subjected to wet type magnetic separation, so that iron ore concentrate and magnetic separation tailings are obtained. According to the process for comprehensively recycling the copper and the iron, starting from the high-temperature molten slag generate in the copper smelting process, smelting slag ore phase restructuring is conducted by fully utilizing heat of the molten slag; the iron and the copper are each made to form ore easy to separate, and grains of the ore are pushed to grow; and efficient iron recycling is achieved while the copper is recycled successfully.

The invention, belonging to the field of pharmaceutical chemicals, relates to a Thienopyridine alpha-amino benzylphosphonate, a preparation method and an application thereof. concretely, the invention relates to a compound of formula I, its medicinal salt, racemate, stereoisomer, or solvate, wherein each substituent is defined in the specification. The invention further relates to a pharmaceutical composition of the compound. The compound of the invention can effectively resist platelet aggregation and/or protect vascular endothelial cells.

The invention relates to the technical field of transformer production, and discloses a spraying device for transformer production, including a spraying box, a material inlet is opened on the left side of the spraying box, and a drying box is fixedly connected to the right side of the spraying box. The lower end of the right side of the drying box is provided with a discharge port, and the lower end of the right side of the spraying box and the lower end of the left side of the drying box are provided with through holes. The spraying device used for the production of transformers can drive the left and right movement of the spray head through the set slide plate, driven by the electric turntable, and through the cooperation with the slide plate, it can evenly spray the shell of the transformer, ensuring the spraying efficiency. Through the air outlet pipe, under the action of the fan, the wind can be blown into the upper end of the drying box, the heating plate can be used to heat the wind, and the air can be blown on the shell through the air outlet, and the air can be blown through the air collecting hood. The hot air is effectively gathered to ensure the uniform drying of the shell and the drying efficiency.

The invention relates to a window and hole combined flow guide regular filler sheet and a filler. The crest and trough of a corrugated filler sheet are provided with a hole and a window which are communicated to form a window and hole combined structure; an inclination angle is formed between the ripple direction of the corrugated filler sheet and the vertical direction; a regular filler consists of the window and hole combined flow guide regular filler sheets which are parallel to one another and of which the ripple directions are arranged in a staggered mode; and when the tower diameter is larger, a plurality of regular fillers are arranged, and corrugated sheets of the fillers on an upper tray and a lower tray rotate by 15 to 90 degrees. Under the action of fluid velocity and gravity, flowing liquid can be more effectively aggregated due to a hole structure; and a window structure connected with the hole structure is just positioned below the hole structure, so that the liquid flowing down is guided to the crest position on the other side of the filler sheet, the turbulent degree of a gas-liquid phase liquid film between adjacent window bodies is increased, pressure drop is reduced, gas-liquid flux is increased, and the updating of the liquid film and the increase of gas-liquid mass transfer area are more effectively realized.

The invention provides an electric dust collector capable of effectively gathering nano super fine particles like diesel emitted particles (DEP) without adding special devices. In an electric dust collector, a charging unit and a dust collecting unit are set into front stage and back stage, respectively. The dust collecting unit is composed by a parallel plate type high voltage electrode and a parallel plate type high ground electrode which face each other and are set in parallel to separate the space where processing air flows; a plurality of through holes are formed on the whole area of at least one of the two electrode in the decentralized way.

The invention discloses a wafer-level chip packaging structure. The wafer-level chip packaging structure comprises an image sensing chip and a transparent cover plate, wherein metal conductive pattern layers electrically connected with pin bonding pads are arranged on the surface, with the back towards the image sensing chip, of a passivation layer and blind holes respectively. Each supporting cofferdam is composed of a first supporting cofferdam layer and a second supporting cofferdam layer which are placed in a vertically stacked mode, a plurality of continuously arranged V-shaped notched are formed in the inner side face of each second supporting cofferdam layer, arc-shaped notches are formed in the four corners of each second supporting cofferdam layer respectively, a plurality of holes are evenly formed in the surface, in contact with the image sensing chip, of each supporting cofferdam, each metal conductive pattern layer is formed by placing a titanium layer, a copper layer, a nickel layer and a palladium layer in a stacked mode in sequence, and the titanium layers are in contact with the passivation layer. According to the wafer-level chip packaging structure, stress is relieved, the structure is not prone to oxidation corrosion, the response time of a device is shortened, the reliability of a product is improved, and the requirement for continuously covering the inner wall of a deep hole with a high aspect ration with a metal layer can be met.

The invention discloses an anti-blocking type river treatment and sewage blocking device. The device mainly comprises two treatment boxes and two intercepting devices symmetrically arranged between the two treatment boxes; each intercepting device comprises two transmission rollers and an annular transmission network, and each intercepting device is connected with the corresponding position of theside entering water of the treatment boxes through a self-adjusting sliding rail; the upper ends of the two transmission rollers are transversely provided with a water wheel respectively, the upper ends of the two water wheels are provided with a carrier plate, and the side wall of the side entering water of the carrier plate is provided with an intercepting screen plate; and the side wall of theside entering water of each treatment box is provided with an opening, the other three side walls of each treatment box are all in a net structure, and each treatment box is connected with the innerwall of the river channel through the side wall close to one side of the river channel. According to the device, solid waste can be effectively gathered in the treatment boxes, the situation that theannular transmission net is blocked and the like is effectively prevented, and the interception efficiency of the device is kept in a high state all the time.

The invention discloses a protein-photosensitizer co-transmission pH responsive polyamino acid nanogel and a preparation method thereof and belongs to the technical field of biological medicines. Forthe prepared pH responsive polyamino acid nanogel, by taking methoxy polyethylene glycol with an amido group on a single end as a macroinitiator to initiate ring opening polymerization of gamma-benzyl-L-glutamate-N-carboxanhydride or gamma-benzyl-L-aspartate-N-carboxanhydride with one step to prepare a polyamino acid main skeleton, then the tail end of the main skeleton is used for grafting a photosensitizer, and a side chain is modified with cationic molecules to add the protein supporting ability and the lysosome escape ability; and finally, a pH responsive polyamino acid nanogel system is constructed with a core crosslinking reaction, so that the purposes of in-vivo safety transfer, targeted delivery, rapid cellular uptake, in-vivo protein release and photosensitizer activation are realized, and promotion of development of combined therapy of the proteins and photodynamic therapy in the medical field can be facilitated.

The invention discloses a road and bridge construction surface spraying device. The road and bridge construction surface spraying device comprises a storage box for loading paint, a remote control vehicle for loading the storage box, a discharge cavity and a control device, wherein the control device is connected with the remote control vehicle in a bolted mode; the storage box is located above the remote control car, and the remote control vehicle is provided with a groove; the storage box is placed in the groove, and the storage box is fixedly connected with the groove; the storage box is detachably connected with the remote control vehicle through the groove, a material pumping pump is arranged on the right side of the storage box, and feed delivery pipes are connected to a feeding portand a discharging port of the material pumping pump; the feeding port and the discharging port of the material pumping pump are all connected with the corresponding feed delivery pipes on the feedingport and the discharging port in a bolted mode, the feed delivery pipes communicate with the discharge cavity, the feed delivery pipes are connected to the discharge cavity in a bolted mode, and thedischarge cavity is connected with a spraying pipe; and the spraying pipe is connected with the discharge cavity in a bolted mode, and the spraying pipe is provided with a spraying pump. The road andbridge construction surface spraying device can effectively spray uniformly.

A new energy-gathering wind power generation device that adopts the dynamic control of a split-flow wind regulating device, including two wind collecting walls (1) connected with a steel-structured air outlet frame (4) to form a trumpet-shaped wind collecting air duct (2 ) to form a wind energy gathering device, so that the wind speed at the position of the air duct outlet frame (4) is increased, and several high-power wind turbines (6) with miniaturized typhoon wheels are installed on the air duct outlet frame (4). Multi-layer round hole type split flow automatic wind regulator (7) is installed on the wind wall (1), each round hole type split flow automatic wind regulator (7) is connected by a round hole (9) and N folding Sector blade (10) and driving motor (12) constitute. The dynamic control of the automatic wind regulator (7) and the operation of the fixed-pitch two-speed asynchronous generator form a unified cooperative control system. Control and stabilize the operating wind speed of wind turbines, improve the efficiency of wind turbines, increase power generation, and use wind energy more effectively.

The invention relates to water-quenched slag silicate series coagulants and a preparation method thereof, belonging to the field of purification treatment of coking wastewater and high-turbidity wastewater. The coagulants comprise the following materials in a mass ratio, water-quenched slag is more than or equal to 60 meshes, and the mass ratio of sodium carbonate to the water-quenched slag is (0.1-0.5): 1. The water-quenched slag, the sodium carbonate, sulfuric acid and sodium hydroxide are used as raw materials. The preparation method comprises the following steps of: grinding, sieving, roasting with a cosolvent, leaching in acid, washing filter residue after acid leaching, filtering and drying; leaching in alkali: leaching the washed and dried filter residue in the alkali, and filtering; and polymerizing: polymerizing the acid leach and the alkali leach in different polymerization modes and ageing to generate 3 coagulants. By adopting the method, the water-quenched slag extract is polymerized to generate the coagulants, so that a good removable effect on turbidity and chemical oxygen demand (COD) in the coking wastewater and the high-turbidity wastewater is achieved, secondary pollution-free utilization of the water-quenched slag is realized, the production cost is reduced, the treatment effect is good, high value-added utilization of industrial solid wastes is realized, and good ecological and environmental benefits are brought.

The invention discloses a system for controlling the migration of heavy metal elements of a goaf filling body by using an electrophoresis theory. The system comprises a direct current power supply, conductive plates, a screen pipe, a concentration pipeline, a water suction pump, a water storage basin (6) and a water drainage pump. A column of conductive plates which are as long as a coal face arearranged in parallel to the coal face and in a goaf at certain distances; two adjacent columns of conductive plates are connected to different electrodes of the direct current power supply; the screenpipe is laid below the conductive plate connected to a negative electrode of the power supply. Heavy metal ions can be gathered around the conductive plate connected to the negative electrode of thepower supply under the action of an electric field, and then the water suction pump is turned on to enable sewage to pass through the screen pipe and the concentration pipeline and be gathered in an impounding reservoir; finally, the sewage is drained to the ground for treatment through the water drainage pump. The system can effectively control the migration of the heavy metal ions in surroundingrocks of the goaf to reduce pollution, caused by the heavy metal ions of the coal gangue filling body for the goaf, to an underground water environment.