The invention discloses an orthogonal piezoelectric displacement amplifying mechanism which is in a diamond symmetrical structure. Two diagonals of the diamond are mutually perpendicular but not equal in length. Laminated piezoelectric ceramic is disposed along the long diagonal of the diamond. Two corners along the short diagonal of the diamond are provided with a fixed surface and a stress surface respectively. The fixed surface and the stress surface are parallel with the laminated piezoelectric ceramic. Compared with common displacement amplifying mechanisms, the orthogonal piezoelectric displacement amplifying mechanism has the advantages of high amplifying ratio, large output force, fast response, simple structure, easiness in processing, convenience in use, easiness in modularization, resistance to electromagnetic interference and the like. Effective force output is maintained while piezoelectric displacement amplification is achieved. The orthogonal piezoelectric displacement amplifying mechanism is also excellent in dynamic performance. Therefore, as a driver, the orthogonal piezoelectric displacement amplifying mechanism has important value of application to the fields of micrometric displacement mechanical systems, micrometric displacement positioning, proportional values and pumps, nozzles, optical precision instruments, aerospace control and the like.