Medicine crushing processing equipment comprises a bottom plate (1), a frame device (2), a crushing device (3), an air cylinder device (4), a motor device (5), a filtering device (6), a knocking device (7), a recycling device (8) and a pushing device (9). The bottom plate (1) is provided with a first support (11), a second support (12) and a first inclined rod (13). The frame device (2) comprises a feeding hopper (21), a first frame (22), a first vertical rod (23), a first cross rod (24) and a second vertical rod (25). The crushing device (3) comprises a first motor (31), a first rotary shaft (32), a first rotary block (33) and a crushing block (34). The air cylinder device (4) comprises a second cross rod (41), a first air cylinder (42), a third support (43), a third cross rod (44) and the like. The medicine crushing processing equipment can improve medicine crushing efficiency and achieve uniform crushing and grinding.