35results about How to "High polymer content" patented technology

This invention relates to compositions and methods for treating subterranean formations, in particular, oilfield stimulation compositions and methods using water-in-water polymer emulsions to uniformly dissolve a rheologically active polymer, such as a thickener or friction reducer, in the treatment fluid. The emulsions have a low viscosity and are easily pumped for mixing into a treatment fluid, where upon dilution with an aqueous medium, the polymer is easily hydrated without forming fish-eyes. The partitioning agent in the water-in-water emulsion does not generally affect the rheology of the treatment fluid. The invention also relates to further processing of the emulsion by wet grinding, high shear mixing and / or heating to enhance the hydration rate in the preparation of the well treatment fluid.

The invention discloses a process for preparing human serum albumin. According to the process, a low-temperature ethanol separation method is adopted, and the human serum albumin is prepared from human plasma. The process comprises the steps of dissolving plasma; preparing an ingredient I; preparing an ingredient II and an ingredient III; preparing an ingredient IV; preparing an ingredient V; refining the ingredient V; carrying out ultrafiltration; diluting; carrying out pasteurization; sterilizing and packaging albumen; incubating products; and packaging finished products. The process has the advantages that solid-liquid separation is carried out by adopting a pressure filtration technology, so that the albumin yield which is higher than 29 g / L plasma is increased remarkably, the purity is higher than 98%, and the stability of the products is improved remarkably; Zetaplus deep filter-core filtration is combined with the prolongation of pasteurization time, so that the PKA (Protein Kinase A) level of the products is effectively controlled to be lower than 20IU / ml, and the risks of excessive heat source and virus infection in the products are reduced; and during the process, sodium chloride solutions of two gradient concentrations are used for carrying out ultrafiltration, so that not only can the ethanol residual quantity of the products be controlled to be lower than 0.025%, but also the aluminum residual quantity can be effectively minimized to be lower than 50 micrograms / L.

The process and catalyst of this invention can be utilized to synthesize homo and copolymers of conjugated diene monomers and vinyl aromatic monomers having high trans contents of greater than 60% with low melting points. These homo and copolymers of conjugated diene monomers and vinyl aromatic monomers can be utilized in tire tread and sidewall rubbers that exhibit outstanding wear and tear characteristics in the tread and excellent flexing properties in the sidewall. The rubber polymers of this invention are made utilizing an improved catalyst system. This catalyst system is comprised of (a) organo aluminum compounds, (b) organo lithium compounds, (c) a barium compound selected from barium salts of (i) di(ethylene glycol) ethyl ether, (ii) di(ethylene glycol) propyl ether, (iii) di(ethylene glycol) hexyl ether, (iv) di(N,N-dimethyl amino glycol) ethyl ether, (v) menthol and thymol in the presence of polar modifier consisting of water, alcohols, amines, thiols, phosphates and phosphites. The trans polymers and copolymers of this invention made with the above catalyst system typically have a glass transition temperature ranging from −97° C. to −40° C., a melt temperature ranging from −30° C. to +30° C., and a number average molecular weight from 20,000 to 250,000. The inclusion of such polar modifiers in the barium catalyst system results in a high styrene content in copolymerization, a high trans content, and high molecular weight. Copolymers of conjugated diolefin monomers and vinyl aromatic monomers made with the catalyst system of this invention also have a tapered macrostructure.

The invention provides a method for preparing a mercaptosilane coupling agent by using a channel reactor. In a solvent, a channel reactor is utilized to prepare the mercaptosilane coupling agent. The structural general formula of the mercaptosilane coupling agent is XmSiC3H6S(C=O)nY, wherein each X is independently alkyl group, alkoxy group, hydroxy group, R(OR')LO-, -ORO- or N(RO-)3, and at least one X is alkoxy group, hydroxy group or N(RO-)3; Y is hydrogen or alkyl group; R and R' are respectively independently straight-chain or branched-chain alkyl group; the average value of L is 1-30; m is 1, 2 or 3; and n is 0 or 1. The corrected diameter of the channel reactor channel is one micrometer to several centimeters; and the channel reactor is connected with an after-treatment device. The method solves the problems of long reaction period, poor stability, existence of impurity polymers and the like in the large-size reactor, and especially reduces the odor caused by the large-size reactor production.

The invention belongs to the technical field of biological genetic engineering and particularly discloses design, a preparation method and pharmaceutical application of a tumor targeting tumor necrosis factor related apoptosis ligand variant. The tumor targeting tumor necrosis factor related apoptosis ligand variant is fusion protein composed by ligand, connecting peptide and tumor necrosis factor related apoptosis ligand of CD13 and is produced through cloning and constructing of coding genes of the variant, soluble recombination expression and simple separation and purification in a genetic engineering method. The variant generated by the preparation method of the tumor targeting tumor necrosis factor related apoptosis ligand variant has good tumor tissue targeting property, remarkably enhances antitumous effect, can reduce protein administration dosage required for obtaining therapeutic effect, improves bioavailability, lowers treatment cost, and eliminates potential toxic and side effect of the tumor necrosis factor related apoptosis ligand. Simultaneously, the manufacturing method of the tumor targeting tumor necrosis factor related apoptosis ligand variant provides an expression method for producing soluble high-polymer form content and a simple separation and purification process.

An asphalt binder is provided, comprising 85 to 97.5 parts by weight of a bitumen and 16 to 2.5 parts by weigh of a polymer composition, wherein the polymer composition comprises:(i) from 2 to 8, preferably from 3 to 6 parts by weight of a styrenic block copolymer having at least two blocks of monovinylaromatic hydrocarbon (A) and at least one block of a conjugated diene (B), wherein the block copolymer composition has a vinyl content of at least 25% by weight, preferably from 25 to 40% by weight, based on the total diene content;(ii) from 0 to 5, preferably from 1 to 3 parts by weight of a styrenic diblock copolymer having one block of monovinylaromatic hydrocarbon (A) and one block of a conjugated diene (B); and(iii) from 0.5 to 3, preferably from 1 to 2.5 parts by weight of an ethylene-vinyl acetate copolymer,wherein the weight ratio of (i)+(ii):(iii) is from 2:1 to 6:1, preferably from 3:1 to 4:1. In addition, an asphalt mix is provided comprising 2 to 8 parts by weight of the asphalt binder of the present invention and 98 to 92 parts by weight of gap-graded aggregate or open-graded aggregate material.Furthermore, a porous pavement is claimed, produced from the open or gap-graded mixes, by compacting the asphalt mix mentioned above.

The invention provides a method for preparing a mercaptosilane coupling agent by using a channel reactor. In a solvent, a channel reactor is utilized to prepare the mercaptosilane coupling agent. The structural general formula of the mercaptosilane coupling agent is XmSiC3H6S(C=O)nY, wherein each X is independently alkyl group, alkoxy group, hydroxy group, R(OR')LO-, -ORO- or N(RO-)3, and at least one X is alkoxy group, hydroxy group or N(RO-)3; Y is hydrogen or alkyl group; R and R' are respectively independently straight-chain or branched-chain alkyl group; the average value of L is 1-30; m is 1, 2 or 3; and n is 0 or 1. The corrected diameter of the channel reactor channel is one micrometer to several centimeters; and the channel reactor is connected with an after-treatment device. The method solves the problems of long reaction period, poor stability, existence of impurity polymers and the like in the large-size reactor, and especially reduces the odor caused by the large-size reactor production.

The invention discloses a process for preparing human serum albumin. According to the process, a low-temperature ethanol separation method is adopted, and the human serum albumin is prepared from human plasma. The process comprises the steps of dissolving plasma; preparing an ingredient I; preparing an ingredient II and an ingredient III; preparing an ingredient IV; preparing an ingredient V; refining the ingredient V; carrying out ultrafiltration; diluting; carrying out pasteurization; sterilizing and packaging albumen; incubating products; and packaging finished products. The process has the advantages that solid-liquid separation is carried out by adopting a pressure filtration technology, so that the albumin yield which is higher than 29 g / L plasma is increased remarkably, the purity is higher than 98%, and the stability of the products is improved remarkably; Zetaplus deep filter-core filtration is combined with the prolongation of pasteurization time, so that the PKA (Protein Kinase A) level of the products is effectively controlled to be lower than 20IU / ml, and the risks of excessive heat source and virus infection in the products are reduced; and during the process, sodium chloride solutions of two gradient concentrations are used for carrying out ultrafiltration, so that not only can the ethanol residual quantity of the products be controlled to be lower than 0.025%, but also the aluminum residual quantity can be effectively minimized to be lower than 50 micrograms / L.

A wettable, dispersion spun fluoropolymer fiber prepared from non-melt-processible fluoropolymer particles.

The invention belongs to the field of biological technology, and specifically discloses a tumor necrosis factor family cell apoptosis protein fusion protein, a preparation method and application thereof. The fusion protein is composed of annexin, connecting peptide and tumor necrosis factor family cell apoptosis protein, and the coding gene of the fusion protein is constructed by cloning. The tumor necrosis factor family cell apoptosis protein fusion protein has significantly enhanced effect of inducing apoptosis, can induce apoptosis of tumor cells insensitive to cell apoptosis, and can reduce protein dosage required for obtaining therapeutic effect.

The invention relates to a polymer emulsion, and discloses a polymer emulsion and a preparation method thereof. The method includes an emulsification step and at least one step of separating and concentrating the emulsion, combining a polymer solution containing a polymer and an organic solvent with an aqueous solution containing an emulsifier Mixing and emulsifying the mixed solution; the step of separating and concentrating the emulsion includes successive organic solvent removal sub-steps and centrifugal separation sub-steps, the emulsion is subjected to at least one distillation, and the thin emulsion is subjected to at least one centrifugation; the emulsifier is an anion Type emulsifier, the polymer is a polymer formed by homopolymerization and / or copolymerization of dienes or a polymer formed by copolymerization of dienes and C2-C4 alkenyl-substituted aromatic compounds, measured according to HG / T3323-2008 The apparent viscosity of the polymer solution at a concentration of 6-20% by weight at 25°C is 5000-20,000 cP. The method obtains a polymer emulsion with high polymer content, and the product has good stability.

The invention relates to the technical field of the fracturing increase production for the exploitation of shale gas, and discloses a method for preparing a drag reducer for shale gas fracture as well as the drag reducer for the shale gas fracture prepared by the method. The method comprises the following steps: (1) mixing at least part of polymeric monomer, inorganic salt, stabilizing agent and chelating agent in the presence of water to obtain mixed solution; (2) regulating the pH value of the mixed solution to be 2-5; and (3) adding an initiating agent and the remaining part of polymeric monomer into the obtained reaction system for reaction, wherein the weight ratio of the at least part of polymeric monomer to the remaining part of polymeric monomer is 1 to (1 to 20). The drag reducer for the shale gas fracture prepared by the method disclosed by the invention has the advantages of high drag reducing efficiency, high anti-shearing performance, good stability, low viscosity, good flowability, high dissolving speed and environmental protection.

The invention relates to the field of shale gas exploitation, fracturing, and yield increasing, and discloses a preparation method of a drag reducer for shale gas fracturing and a drag reducer prepared by the provided preparation method. The preparation method comprises the following steps: (1) in the presence of water, mixing at least part of polymeric monomers, inorganic salts, a stabilizer and a chelating agent to obtain a mixed solution; (2) adjusting the pH of the mixed solution to 3-7; and (3) adding an initiator and residual polymeric monomers into the reaction system obtained in the step (2) to carry out reactions; wherein the weight ratio of at least part of polymeric monomers to residual polymeric monomers is 1:1-20. The shale gas fracturing drag reducer prepared by the provided preparation method has the advantages of high drag reducing efficiency, strong shearing resistant performance, low viscosity, good fluidity, quick dissolving speed, and environment-friendliness.

The invention discloses an oil-based self-suspension polymer thickener and a preparation method thereof, belongs to the field of oil field stimulation chemical agents, and relates to a thickener for fracturing fluid. The thickener of the present invention obtains a certain self-suspension performance by modifying the polymer, and adding it to solvent oil to obtain the oil-based self-suspension polymer thickener suspension. The polymer of the thickener of the present invention is self-suspended in mineral spirits, without adding other auxiliary agents such as stabilizer, cutting agent, suspending agent, etc., and has the advantage of high polymer content of the suspension-type thickener without additional With the addition of suspending aids, the residue content of gel breaking solution is low and the demulsification rate is high.