The invention relates to the technical field of building partition materials, in particular to a waterproof gypsum environmental-friendly building block. The waterproof gypsum environmental-friendly building block is produced through the steps of stirring beta semi-hydrated gypsum, a water reducing agent, an inorganic material and a composite water-proofing agent, adding water and performing casting, wherein the percentage by weight of the raw materials is that the weight of the inorganic material is 9-15% of that of the beta semi-hydrated gypsum, the weight of the water reducing agent is 0.4-0.7% of that of the beta semi-hydrated gypsum, the weight of the composite water-proofing agent is 0.7-1.2% of that of the beta semi-hydrated gypsum, and the weight of the water is 58-70% of that of the beta semi-hydrated gypsum. Compared with the prior art, the environmental-friendly building block disclosed by the invention is produced through the following steps of mixing and stirring the beta semi-hydrated gypsum, the inorganic material, the water reducing agent and the composite water-proofing agent, then adding the water, and performing casting and shaping so that the problems that the coagulation time is too long, productivity is difficult to form, the intensity is low, the cost is high, and efflorescence and mildewing occur, are solved.