The invention relates to a recirculating prawn aquaculture method in combination with a nitrification-assimilation effect and belongs to the technical field of aquaculture. A culture system used in the method comprises a culture pond, a microfilter, a water circulating pump, a biofilter, an ultraviolet sterilization device and a Roots blower; when the culture system is utilized for culture, browngranulated sugar 40-50% of the bait feeding amount or molasses 50-60% of the bait feeding amount is added into the culture pond every day to promote growth of heterotrophic bacteria, and part of metabolic waste is removed by utilizing the bacterial assimilation effect. According to the method, in the circulating water culture system with nitrification as a water treatment core, a carbon source iscontinuously increased in the culture process, growth of the rhodobacteriaceae bacteria in a culture water body is promoted, the bacterial assimilation effect is strengthened, meanwhile, the nitrification effect of nitrification bacteria is not inhibited, the assimilation effect and the nitrification effect jointly purify the water body, the microbial water treatment efficiency is improved, the load of a water treatment system is reduced, and a culture water environment is improved.