This application discloses a self-powered knee jointguidance system based on human bodynegative energyrecovery, comprising: a knee brace body; a first transmission mechanism disposed on the knee brace body for converting the reciprocating motion of the lower limbs during walking into the reciprocating linear motion of a double-rotating screw; a motion conversion mechanism for converting the reciprocating linear motion of the double-rotating screw into rotational motion; a power generation mechanism for converting the mechanical energy generated by the rotational motion into electrical energy; a power management module for processing and storing the electrical energy generated by the power generation mechanism; and a guidance function module powered by the power management module for sensing environmental obstacles and providing warning information to the user. This application provides a wearable, self-powered, and intelligent guidance solution.