The invention relates to the field of food condiments, in particular to hot and spicy sauce. The hot and spicy sauce is prepared from, by weight, 100-300 parts of dry chillies, 500-750 parts of sesame oil, 5-9 parts of Chinese prickly ash oil, 30-55 parts of bean paste, 15-35 parts of monosodium glutamate, 30-45 parts of Chinese prickly ash, 10-25 parts of apricot kernels, 10-15 parts of rice wine, 18-34 parts of aniseeds, 6-8 parts of pickled chillies, 9-18 parts of soybean sauce, 35-54 parts of water, 40-60 parts of garlic, 24-36 pats of fresh ginger and 20-48 parts of minced pork. The hot and spicy sauce is rich in aroma, good in color, salty, hot, palatable, fresh and mellow in taste and long in shelf life, and a user will not get inflamed when eating the hot and spicy sauce.