The invention discloses an ultra-supercritical secondary re-heating steam turbine set. The ultra-supercritical secondary re-heating steam turbine set comprises a first bearing box, an ultra high pressure-high pressure cylinder, a second bearing box, a medium-pressure cylinder, a third bearing box, a first low-pressure cylinder, a fourth bearing box, a second low-pressure cylinder and a turning gear box which are assembled on a rotor in sequence. The capacity of the steam turbine set is 1000-1300MW, the ultra high pressure-high pressure cylinder is of a cylinder combined structure, the pressure of a steam inlet of an ultra high pressure part is 30-35MPa, the temperature is 600 DEG C, the pressure of a primary re-heating steam inlet of a high pressure part is 10MPa, the temperature is 610-630 DEG C, the medium-pressure cylinder, the first low-pressure cylinder and the second low-pressure cylinder are respectively of a double-flow-division structure, the medium-pressure cylinder provides steam for the first low-pressure cylinder and the second low-pressure cylinder respectively through communication pipes, the pressure of a secondary re-heating steam inlet of the medium-pressure cylinder is 2.8MPa, and the temperature is 610-630 DEG C. The ultra-supercritical secondary re-heating steam turbine set has the advantages of being large in capacity, high in parameter, small in occupied space, low in investment cost, stable and reliable in operation and obvious in economical benefit, saving energy, reducing consumption and the like.