The invention discloses a warship board multilayer anti-detonation protection structure. The warship board multilayer anti-detonation protection structure comprises a double-layer shell, a void compartment, a first liquid compartment and a second liquid compartment, wherein the double-layer shell, the void compartment, the first liquid compartment and the second liquid compartment are sequentially ranked from the outer side of a warship body to the inner side of the warship body, the water filling height h of the first liquid compartment and the water filling height h of the second liquid compartment are 70%-80% of a compartment height H, the void compartment is separated from the first liquid compartment through a first compartment separation plate, the first liquid compartment is separated from the second liquid compartment through a second compartment separation plate, the second liquid compartment is separated from an inner compartment of a warship through a third compartment separation plate, and the side, towards a compartment body, of the second liquid compartment is fixedly connected with a plurality of longitudinal box girders which are vertically ranked at intervals. The warship board multilayer anti-detonation protection structure with the structural style has the advantages of being light in weight, good in anti-detonation performance, high in residual intensity and the like, when a warship board is impacted by detonation, most detonation impact energy can be absorbed, the compartments of the warship are prevented from being damaged, and personal losses are avoided.