An in-situ injection of soil and groundwater—high pressure rotary jet grouting in-situ remediation system and method. The system has an agent dispensing station, high pressure grouting pump, air compressor, rotary jet grouting drilling machine, second double-pipe water flow joint, automatic lifting mechanism for grouting drill pipe of rotary jet grouting drilling machine, high pressure jet drill pipe, inner tube for high pressure jet triple drill pipe, outer tube for high pressure jet triple drill pipe, agent jet nozzle, an air jet nozzle, cemented carbide block and a drill bit. Parameters are arranged according to the triangle method to ensure that the remediation area is covered within the diffusion radius of the agent. After positioning the GPS measuring point, a guided-boring rig is positioned at the center of the injection point. The high pressure injection remediation uses a double-pipe: using gas and liquid fluids to spread the soil while cutting the soil from bottom to top to achieve thorough mixing of the remediation agent with soil and groundwater; quickly combining laboratory testing to obtain parameters for remediation agent residues, pH values, and contaminant concentrations to verify the in-situ remediation effect and monitor the residual agent.