The invention discloses a preparation method of an environment-friendly and sound-insulating wood-plastic wall material. The preparation method comprises steps as follows: a, wood fiber materials, montmorillonite, wood leftover materials, manganolite, fluorapatite, Jutecell fibers, antimony trioxide, silicone powder, silkworm excrement, carbonized graphite and vermiculite powder are added to a high-speed mixer, a coupling agent solution is dropwise added, the mixture is heated and stirred, and a mixture M is obtained; b, after the mixture M is cooled, sebacic acid dibutyl ester, azelaic acid dibutoxy ethyl ester, butyl acrylate, diisopropylbenzene hydroperoxide, dioctyl phthalate and maleic anhydride grafted polyethylene are added, the mixture is stirred uniformly, and a mixture N is obtained; c, the mixture N is extruded and granulated, and master batch is obtained; d, the master batch obtained in the step c is processed and formed, and the wood-plastic wall material is obtained. According to the prepared wood-plastic wall material, the problems that a conventional sound-insulating wall material is prone to ageing and has poor thermal insulation and sound insulation effects are solved.