A two-degree-of-freedom motion decoupling flexible hinge mechanism, the mechanism includes a flexible hinge base and a drive branch, wherein the flexible hinge base includes a flexible hinge branch and a rigid connector, and the rigid connector includes a terminal located in the middle part of the flexible hinge base The rigid output platform and the upper, lower, left, and right rigid platforms respectively located on the upper, lower, left, and right parts of the flexible hinge base; the upper, lower, left, and right rigid platforms respectively pass through the flexible hinge branch chain and the terminal rigid output platform connected, and the upper, lower, left, and right rigid platforms are respectively connected to the rigid base of the flexible hinge base through flexible hinge branches. The two-degree-of-freedom motion decoupling flexible hinge mechanism of the present invention can realize the decoupling between the terminal's all-directional motion and force, thereby helping to improve the motion accuracy of the two-degree-of-freedom motion decoupling flexible hinge mechanism.