The invention provides a multi-agent adversarial decision-making method based on cooperative reinforcement learning and transfer learning, and the method is characterized in that the method comprisesthe following steps: defining the state space S = {s1, s2,..., sn} of an agent; setting an action space A to be equal to {a1, a2,..., an}; setting a value function matrix of the agent reinforcement learning model; calculating a value function sequence corresponding to the current state st by using an action evaluator, and selecting a corresponding action at through an action selector based on simulated annealing and softmax strategy; meanwhile, the state of the intelligent agent is changed, and the intelligent agent is transferred to the next state st + 1. After the action at is executed, theintelligent agent obtains a reward signal rt from the environment; the loss of experience storage can be reduced through a weight sharing mode, and the adversarial decision-making efficiency is improved. Through the migration learning method based on the attenuation function, the agent can reuse previous experience with a gradually decreasing probability, and the migration learning migrates the previously trained action evaluator weight to more adversarial decision scenes, thereby improving the generalization of the learning model.