42 results about "D methionine" patented technology

The composite amino acid and vitamin capsule preparation includes coated amino acid granules and coated vitamin granules in the weight ratio of 1 to 0.68. The coated amino acid granules include isoleucine, leucine, lysine hydrochloride, phenylalanine, methionine, threonine, tryptophan, valine and arginine hydrochloride; and the coated vitamin granules include vitamin B1 nitrate, vitamin B2, vitamin B6, vitamin E acetate, and nicotinamide. The present invention also provides the preparation process of the composite amino acid and vitamin capsule preparation.

The invention relates to a method for recovering N-acetyl-DL-methionine from N-acetyl-DL-methionine racemization waste liquid. The method comprises the steps as follows: (1) N-acetyl-D-methionine racemization mother liquor is adjusted through NaOH of 30 percent until the pH value ranges from 3 to 10; (2) N-acetyl-D-methionine racemization mother liquor the pH value of which is adjusted is decompressed and concentrated until the volume thereof is about a quarter to three-quarter of the original volume; (3) a lot of sodium chloride solids are separated out after decompressing concentration, andcan be removed through filtration when the temperature of mother liquor ranges from 20 to 80 DEG C; (4) filter liquor is pumped in a cooling kettle, the stirring is carried out, the temperature fallsto reach 0 to 30 DEG C, and sodium acetate trihydrate crystals are obtained through centrifugation; and (5) mother liquor without sodium acetate is adjusted through HCl of 30 percent until the pH value ranges from 1 to 3, the temperature falls to reach 5 to 7 DEG C, stirring is carried out, and N-acetyl-DL-methionine crystals are obtained through crystallization. The method has the advantages of high recovery rate and the like, is simple and convenient to operate, and is environmental-friendly. Through practical production calculation, the yield coefficient of active substances of N-acetyl-DL-methionine can reach more than 85 percent by adopting the method.

Methods of preventing or reducing hearing or balance loss and damage to ear cells in patients who have been exposed to toxic levels of noise are provided. These methods comprise administering an effective amount of a methionine protective agent, such as D-methionine, prior to, simultaneously with, or subsequently to exposure to noise. Combinations of these time periods can also be employed.

The invention relates to the field of the chemical industry, in particular to a method for preparing N-methylol group-D,L-calcium methionine microelement chelates. The method is environmentally friendly and low in cost. According to the method, saponification liquid produced in the production process of D,L-methionine serves as production raw materials and reacts with trace metal element calcium salt to obtain D,L-methionine microelement chelates, the obtained D,L-methionine microelement chelates react with formaldehyde in a water medium, filtering, washing in cold water, drying and crushing are carried out after the reaction, and the powdered N-methylol group-D,L-calcium methionine microelement chelates are obtained. According to the method, high-purity D,L-methionine is needless, the N-methylol group-D,L-calcium methionine microelement chelates are directly prepared through the saponification liquid, and production cost is reduced. According to the method, the high-purity N-methylol group-D,L-calcium methionine microelement chelates are prepared, stability is high, animals can easily digest and absorb the N-methylol group-D,L-calcium methionine microelement chelates, the N-methylol group-D,L-calcium methionine microelement chelates can serve as feed additions, obtained filter liquor can be recycled, and the method is environmentally friendly.

A process for preparing selenoic methionine by methyleneseleno propanal method includes preparing the important intermediate, methyleneseleno propanel, from methyleneselenol, acroleic acid relative compounds by chemical synthesis, and chemically synthesizing selenoic methionic from it along with se and methionine by conventional process. The resultant product has excellent more bioactivities and the insulin-like action, so it can be used for treating diabetes.

The composite amino acid and vitamin capsule preparation includes coated amino acid granules and coated vitamin granules in the weight ratio of 1 to 0.68. The coated amino acid granules include isoleucine, leucine, lysine hydrochloride, phenylalanine, methionine, threonine, tryptophan, valine and arginine hydrochloride; and the coated vitamin granules include vitamin B1 nitrate, vitamin B2, vitamin B6, vitamin E acetate, and nicotinamide. The present invention also provides the preparation process of the composite amino acid and vitamin capsule preparation.

The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.

This invention is associated with the method of preparation of L- Methionine -15N and D- Methionine -15N with enzymatic resolution. This method uses dissociate aspergillus oryzae mycelium cell or directly split DL- Methionine -15N with aminoacylase. It uses racemic acetyl- Methionine -15N (N-AC-DL-Met-15N) as raw material, and uses aminoacylase (EC.3,5,14) in dissociate aspergillus oryzae mycelium cell or aminoacylase powder as hydrolysis catalyst. The L- Methionine -15N and D- Methionine -15N obtained by this method have high output. It also has high chemical purity and optical purity.

The invention discloses a preparation method of methionine-chelated iodine for feed and belongs to the field of feed additives. Raw materials adopted for producing methionine-chelated iodine include methionine, iodine and a 10% sodium hydroxide water solution. Through preparation of the water solution, a chelation reaction of methionine and iodine, separation, drying and other processes, methionine-chelated iodine is prepared and has the technical advantages that industrial production of methionine-chelated iodine is achieved, the processes are simple, the generation cost is low, there is no need to add important equipment, the operation is convenient, and popularization is easy. The feed prepared by methionine-chelated iodine has high palatability and absorption rate and is easy to transport, and iodine has the functions of promoting biological oxidation, regulating synthesis and decomposition of protein, promoting metabolism of sugar and fat, regulating metabolism of water and salt,promoting the absorption and utilization of vitamins, enhancing the activity of enzymes, facilitating growth and development and the like. Therefore, iodine is one of indispensable trace elements in animal feed, and the absorption rate after iodine is chelated with amino acids is greatly increased, so that the growth performance of animals is improved.

The invention discloses a fermentation production method of S-adenosylmethionine and a separation method of D-methionine. In the methods, in the production process of the S-adenosylmethionine with yeast, cheap DL-methionine is used to substitute L-methionine, and the D-methionine in the DL-methionine can be separated for use. The invention has the advantages of reducing the cost on producing the S-adenosylmethionine by a fermentation method and simultaneously obtaining the separated D-methionine with wide application range.

The present invention relates to a novel protein having O-acetylhomoserine sulfhydrylase activity, a mutant protein thereof, a polynucleotide encoding the same, a recombinant vector comprising the polynucleotide, a microorganism transformed with the recombinant vector, and a method for producing methionine or acetic acid using the protein. The production method of the present invention has the advantage of producing L-methionine and acetic acid cost-effectively through having higher conversion rate and reduced reaction time compared to the existing methods, and it can minimize the amount of enzyme homogenate added when using the mutant protein, thereby easily producing L-methionine and acetic acid at high yield.