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4 results about "Endospore Forming Bacteria" patented technology
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Endospore formation is usually triggered by a lack of nutrients, and usually occurs in gram-positive bacteria. In endospore formation, the bacterium divides within its cell wall. One side then engulfs the other. Endospores enable bacteria to lie dormant for extended periods, even centuries.
Metal-Binding Bacterial Protein Fibers
PendingUS20260139013A1Polypeptide with affinity tagAntibody mimetics/scaffoldsMicrobiologyBioremediation
The present invention relates to the field of bacterial protein engineering and protein fibers applicable as metal-binding bionanomaterials. More specifically, the present invention relates to engineered bacterial endospore appendage (Ena) proteins modified to contain metal-binding polypeptide (MBP) inserts providing for stable, flexible and robust protein assemblies with metal-binding activity. In particular, the invention relates to methods for designing Ena-fusion proteins capable of self-assembling into fibers, and for recombinant production of said self-assembling Ena-MBP fusion protein subunits, assemblies and fibers, ensuring a sustainable source of biological material for use in metal mineralization, metal sequestration, and metal-removal applications such as waste water treatment, water softening, or bioremediation.
Owner:VLAAMS INTERUNIVERSITAIR INST VOOR BIOTECHNOLOGIE VZW +1
Alpha-helical protein nanofibrils
This invention relates to the field of microbial self-assembled protein fibrils as novel bionanomaterials. More specifically, this invention relates to protein nanofibril materials comprising Bacillus endospore appendage (ENA) proteins, which are spontaneously folded helical hairpin subunits assembled into α-helical multimers (A-ENA) fibrils having a hydrophobic core and covalently linked by one or more isopeptide bonds, providing nanofibrils with high stability and tensile strength. This invention also relates to said protein nanofibrils being engineered or modified to provide functionalized bionanomaterials. In particular, this invention relates to methods for the recombinant preparation of said self-assembled protein nanofibrils, and their use in modifying bacterial endospores and endospore activity or pathogenicity.
Owner:VLAAMS INTERUNIVERSITAIR INST VOOR BIOTECHNOLOGIE VZW +1
Methods for stabilizing liquid bacterial endospore compositions
The present invention relates to methods for stabilizing liquid bacterial endospores compositions. The present invention also relates to multi-functional osmotic preservation strategies for liquid Bacillus endospore suspensions.
Owner:BIOWISH TECHNOLOGIES INC +1
A high-purity multifunctional powder of probiotics and a preparation method thereof
This invention discloses a high-purity, multifunctional probiotic powder and its preparation method. Based on the different characteristics of lactic acid bacteria, Bacillus subtilis, and actinomycetes, this invention employs different methods for their respective proliferation. This not only avoids potential mutual interference and contamination during their individual proliferation processes but also achieves high viable cell counts while maintaining high purity, and the high viable cell count is maintained even after mixing. This invention mixes the proliferated bacterial powders in a reasonable ratio, allowing lactic acid bacteria to be the dominant strain while fully utilizing the functional characteristics of each of the three bacteria: lactic acid bacteria are anaerobic, while Bacillus subtilis and actinomycetes are aerobic. The latter can absorb oxygen released by the former, ensuring that in the anaerobic environment of the human intestine, Bacillus subtilis and actinomycetes remain active rather than dormant, generating resistant endospores through synergistic action with lactic acid bacteria.
Owner:赵文宁