35 results about "Gold Compounds" patented technology

The invention relates to the field of precious metal recovery, and particularly discloses a method for recovering gold from gold ion electrolysis tail liquid. A method for recycling gold from gold ion electrolysis tail liquid comprises the following specific steps that S1, ion exchange adsorption is conducted, specifically, after a mixed bed is cleaned, ion exchange resin is soaked with a sodium hydroxide solution and then loaded into the mixed bed, and then the gold ion electrolysis tail liquid is added for ion exchange adsorption; the ion exchange resin adsorbing the gold tail liquid is dried and carbonized to obtain a gold-containing compound, the gold-containing compound and aqua regia are mixed and dissolved, hydrochloric acid is used for denitration to obtain gold aqua regia, vacuum filtering and washing are conducted, then anhydrous sodium sulfite is used for reduction to obtain reduced gold powder, and the gold powder is obtained after drying; the ion exchange resin raw materials comprise cation exchange resin and carboxymethyl chitosan; through the synergistic effect of all the processes, the adsorption capacity and the adsorption rate of the ion exchange resin can be enhanced, and the gold recovery effect is improved.

Provided herein are methods composition for treating lung cancer in a subject in need thereof, the method comprising administering to the subject an effective amount of an imidazolate gold compound according to Formula I, or a pharmaceutically acceptable salt, racemate, or enantiomer thereof, wherein Formula I is a gold complex having a structure Au(L)(L′)n, wherein: n is an integer from 1 to 3; L is an imidazolyl-based N-heterocyclic carbene (NHC) ligand; and each L′ is independently selected from an imidazolyl-based NHC ligand, a triaryl phosphine, or a halide.

Described herein are a novel concept of thermally stimulated delayed phosphorescence (TSDP) to harvest light emission from the higher energy triplet excited state via the up-conversion from the lowest-energy triplet excited state by efficient spin-allowed reverse internal conversion as well as the development of TSDP emitters, as exemplified by a novel class of gold(III) compounds with TSDP properties and methods of making and using said compounds. The gold(III) compound includes a triazine-containing cyclometalating tridentate ligand and one auxiliary ligand, both coordinated to a gold(III) metal center. The gold(III) compounds disclosed herein can be used as light-emitting material for fabrication of OLEDs.

The objective is to provide an aqueous solution of gold(I) compounds that can be used as a gold source for gold plating solutions without causing precipitation over a wide pH range and with long-term oxidation stability. [Solution] An aqueous solution of a gold(I) compound having a structure represented by the following general formula (1), wherein the cyanide concentration is 500 mg / L or less, the sulfite ion concentration is 1000 ppm by mass or less, and the halogen ion concentration is 1000 mg / L or less. RS - -Au-S-(CH2) n -SO3 - ...(1) (In formula (1), R is an organic group having at least one group selected from the group consisting of a sulfonic acid group, a carboxyl group, and an amino group at its terminal or side chain, and n is an integer from 3 to 10.)

The invention discloses a synthesis method of an AuGa2 compound, the AuGa2 compound and application, and relates to the technical field of preparation of gold-containing compounds. According to the method, a gold source and liquid gallium are used as raw materials, the liquid gallium is used as a pressure medium for pressurization before reaction, and the reaction process is carried out under pressurized and closed conditions. According to the new path for synthesizing the AuGa2 compound, high-temperature or electric arc melting is not needed, the argon atmosphere requirement is avoided, meanwhile, the power consumption in the synthesis process is very low, the reaction time is very short, and carbon dioxide emission and related potential safety hazards can be reduced. Therefore, the synthesis method provided by the invention can greatly reduce the process cost, and is more energy-saving and environment-friendly.

The invention discloses a synthesis method and a use method of large-particle gold-silver core-shell structure composite nanoparticles. According to the method, an acetic acid-chlorine-gold compound solution is prepared through the steps of dissolving, concentrating, crystallizing, washing and the like, and a pure gold salt solution without halogen is obtained, so that halogenated precipitates are prevented from being generated on the surface of a silver core. Meanwhile, ascorbic acid is adopted as a reducing agent to control the reaction to be mild, and the gold-shell silver-core nanoparticles which are stable in structure and uniform in coating are obtained. According to the method, the composite nanoparticles which are high in purity and firm in wrapping are provided, the method is suitable for the fields of immunodetection, surface enhanced Raman scattering and the like, the material cost is effectively reduced, and the detection effect is improved.

Disclosed are pharmaceutical compositions containing (a) polymyxin antibiotic and (b) a mobile colistin resistant proteins (MCRs) inhibitor. The inhibitor relates to silver / gold-compounds or the pharmaceutically acceptable salts thereof. Also disclosed are methods of making silver / gold-compounds or the pharmaceutically acceptable salts thereof and methods for treating MCR-producing bacterial infection via multiple mechanisms.

Gold compounds and pharmaceutically acceptable salts thereof are disclosed. Certain compounds and salts are active as antibacterial, antifungal, and / or anti-parasitic agents. The disclosure provides pharmaceutical compositions containing the gold compounds. Methods of using the gold compounds to treat bacterial infections are disclosed.

The application discloses a kind of integrated circuit chip package lead frame's electroless gold plating solution and its gold plating method, it is related to integrated circuit chip packaging field.Therein, electroless gold plating solution is following concentration component aqueous solution: water-soluble gold compound, with Au, concentration is 1-1.5g / L;Sodium hypophosphite 10~20g / L;Malic acid 15~20g / L;Citric acid 15~20g / L;N,N'-bis (2-hydroxyethyl) ethylenediamine 10~15g / L;Triammonium citrate 15~20g / L;EDTA-2Na 5~10g / L;5,5'-dimethyl hydantoin 5~10g / L;Metal ion catalyst, with metal ion, concentration is 2~3ppm;Mercaptoimidazole 0.01~0.015g / L;Hexamethylenetetramine 5~10g / L.The electroless gold plating solution in the application can consider stability, high deposition rate and plating layer deposition uniformity.

The present invention provides a method for producing a catalyst that makes it possible to produce vinyl acetate with improved selectivity while ensuring high catalytic activity. Provided is a method for producing a catalyst that is for vinyl acetate production and that contains a carrier, palladium, gold, copper, and an acetate, said method comprising: step 1, which is for impregnating an alkaline solution into the carrier; step 2, which is for causing a solution containing a compound that includes palladium, a compound that includes gold, and a compound that includes copper to come into contact with and impregnate the carrier; step 5, which is for performing a liquid phase reduction treatment in the range of 0-15°C; and step 6, which is for causing the carrier to support the acetate.

Methods of treating lung cancer in a subject in need thereof are provided, including administering to the subject an effective amount of an imidazolate gold compound according to Formula I, or a pharmaceutically acceptable salt, racemate, or enantiomer thereof:wherein R1 and R2 are independently selected from the group consisting of halo, cyano, hydroxyl, carboxyl, alkyl, aryl, esteryl, amidyl, and alkoxyl. Methods of inducing ferroptosis in a lung cancer cell and pharmaceutical compositions are also provided.

The invention relates to organic gold paste, a gold film and application of the organic gold paste and the gold film, and belongs to the technical field of conductive materials containing metal or alloy. The organic gold paste comprises an organic gold compound, an organic silicon compound and an organic carrier, the temperature for the organic silicon compound to form the nano silicon dioxide through thermal decomposition is less than or equal to 700 DEG C. A gold film formed by the organic gold paste has relatively low volume resistivity, good surface flatness and excellent wear resistance and scratch resistance.

The invention relates to a catalyst for preparing vinyl acetate and a preparation method and application thereof, and the preparation method comprises the following steps: mixing and kneading superfine silica powder, superfine diatomite, silica sol and a boron compound according to the weight ratio of 100: (5-20): (10-60): (0.1-1), drying, molding, and roasting at 150-650 DEG C for 1-6 hours to prepare a boron-doped composite SiO2 carrier; according to the molar ratio of Pd / (Au + Pd) being 0.76-0.93 and the mass of the carrier being 0.5%-1%, carrying out isovolumetric rolling impregnation by using a palladium and gold compound solution, and then drying; treating for 0.5-30 hours by using an alkaline solution, drying, reducing for 1-6 hours at the temperature of 300-650 DEG C in a nitrogen-hydrogen atmosphere, washing with water until no chlorine exists, and drying; mixing copper acetate and rhenium oxide with 0.5%-3% of aluminum phosphate according to the molar ratio of Cu / (Re + Cu) of 0.93-0.97 and 0.3%-1% to prepare dilute sol, dipping, coating and drying; dipping in a potassium acetate solution according to the proportion of 0.2%-7.5%, and carrying out negative pressure heat treatment at 60-200 DEG C for 1-6 hours; the obtained high-stability long-life catalyst is high in strength and few in by-products.

The invention discloses a preparation method of mesoporous plasmon nanoparticles and application of the mesoporous plasmon nanoparticles in an optical excitation gas sensor. The preparation method of the nanoparticles comprises the following steps: dissolving a gold-containing compound in water, adding a reducing agent, and heating for reaction to obtain a colloidal gold solution; adding water and a second reducing agent, and stirring to obtain a gold nanoparticle aqueous dispersion; adding an organic solvent, a surfactant and a pore expanding agent, emulsifying, adding a dopamine precursor, adjusting the pH to be alkaline to form a mesoporous polydopamine shell layer, and washing and drying; and finally, dipping in a tin-containing compound solution, and carrying out calcination treatment. The prepared mesoporous plasmon nanoparticles can be applied to preparation of optical excitation gas sensors. The sensor has high sensitivity and high selectivity response to NO2 gas, can stably work at room temperature, and shows excellent response performance to the NO2 gas concentration range of 0.2-10 ppm.

The invention relates to the technical field of preparation of anti-cancer drugs, in particular to a Schiff base gold (III) compound and a preparation method and application thereof.The series of symmetric or asymmetric Schiff base gold (III) compounds are synthesized on the basis of the bioisostere principle in combination with a Schiff base ligand, the cyclohexanediamine structure and the NNOO coordination mode of oxaliplatin are reserved, platinum (II) is replaced with gold (III), and the Schiff base gold (III) compound is synthesized. Meanwhile, the invention relates to application of the Schiff base gold (III) compound in preparation of anti-hepatoma drugs, the defects that oxaliplatin is strong in side effect and the like are overcome, in-vivo and in-vitro experiment results of the Schiff base gold (III) compound provided by the invention show that the compounds Au3 and Au7 are remarkable in anti-hepatoma activity and can target thioredoxin reductase (TrxR) and mitochondrial DNA (mtDNA) at the same time, and the Schiff base gold (III) compound can be used for preparing anti-hepatoma drugs. The further mechanism research shows that the compound can promote the generation of reactive oxygen species (ROS) to cause endoplasmic reticulum stress (ERS) and mitochondrial injury and finally induce pyroptosis and immunogenic cell death, and has great application potential.

The application discloses synthesis of a novel Schiff base gold (III) compound and antibacterial application thereof, and belongs to the technical field of medicine preparation; gold sodium aurothiomalate has significant antibacterial activity, but the Au-S bond thereof is easily broken by intracellular reducing thiol, and the gold sodium aurothiomalate is metabolized before reaching a target point to produce toxic side effects; based on the gold sodium aurothiomalate, developing a gold compound with stronger stability is one of strategies for overcoming drug-resistant bacteria; the Schiff base itself has antibacterial activity, and after being combined with gold (III) ions, the Schiff base can stabilize gold atoms and improve the activity of the gold atoms; in vitro antibacterial activity shows that Au6 and Au13 have significant antibacterial advantages on carbapenem and polymyxin-resistant Klebsiella pneumoniae, the minimum inhibitory concentration (MIC) is 10 micromoles, and the antibacterial activity is at least 16 times higher than that of the gold sodium aurothiomalate; in vivo antibacterial activity experiments prove that Au6 and Au13 can reduce mouse skin infection and promote wound healing, and can prolong the survival time of abdominal infection mice, and have important practical application value.

The invention discloses synthesis and antibacterial application of a novel Schiff base gold (III) compound, and belongs to the technical field of medicine preparation. Golden nofen has remarkable antibacterial activity, but an Au-S bond of the gold nofen is easily damaged by reducing thiol in cells and is metabolized before reaching a target spot to generate toxic and side effects, and development of a gold compound with higher stability based on the gold nofen is one of strategies for overcoming drug-resistant bacteria; schiff base has antibacterial activity and can stabilize gold atoms and improve the activity of the gold atoms after being combined with gold (III) ions; in-vitro antibacterial activity shows that Au6 and Au13 have remarkable antibacterial advantages on carbapenems and polymyxin-resistant klebsiella pneumoniae, the minimum inhibitory concentration (MIC) is 10 mu M, and the antibacterial activity of Au6 and Au13 is improved by at least 16 times compared with that of Jinnofen; in-vivo antibacterial activity experiments prove that Au6 and Au13 can reduce mouse skin infection, promote wound healing and prolong the survival time of mice with abdominal infection, and have important practical application value.

A gold electroplating solution includes a gold (III) cyanide compound, a chloride compound, and hydrochloric acid. The gold (III) cyanide compound is potassium gold (III) cyanide, ammonium gold (III) cyanide, or sodium gold (III) cyanide. The chloride compound is potassium chloride, ammonium chloride, or sodium chloride. Various structures may be made with the gold electroplating solution having a gold layer deposited directly on the stainless steel (SST) layer using a photolithography process. Such structures include a gold pattern having a discontinuous pattern, a bond pad region having one or more traces on the opposite side of the dielectric layer, a gimbal having gold bond pads, and a bonding joint having an electrical interface including a gold layer.

Presented is a method for making a catalyst that can produce vinyl acetate with very high selectivity while ensuring high catalyst activity. A method for preparing a catalyst for the production of vinyl acetate comprising a carrier, copper, palladium, gold and acetate, the method comprising the following steps: Step 1) a step for impregnating the carrier with an alkaline solution; Step 2) a step for impregnating the carrier with a solution containing a copper-containing compound, a palladium-containing compound and a gold-containing compound; Step 3) a step for carrying out a reduction operation; and Step 4) a step for causing the carrier to carry acetate.

The present invention relates to the field of organic light-emitting materials, and specifically relates to a chiral gold(III) compound, a preparation method therefor, and an application thereof. Provided is a chiral gold(III) compound which exhibits thermally activated delayed fluorescence, and has a short luminescence lifetime and a high decay rate. Because the performance of organic light-emitting diodes is closely related to the luminescence lifetime of the chiral gold(III) compound, an organic light-emitting diode made on the basis of the described compound has good device properties, such as high external quantum efficiency and reduction of efficiency roll-off under actual high-brightness use. In addition, the chiral gold(III) compound is a circularly polarized light-emitting material, and experiments have detected that enantiomers of the chiral gold(III) compound can respectively emit left-handed circularly polarized light and right-handed circularly polarized light of a certain strength; circularly polarized light-emitting materials have potential application value in a wide range of fields, such as planar 3D display, optical storage, optical sensors, and optical anti-counterfeiting.

The application relates to the technical field of metal organic complexes, in particular to a chiral Au 16 Metal complex and preparation method and application thereof. By using a specific chiral 1,4-di (dithiocarbamate) -2-methyl piperazine potassium salt ligand, a specific chiral Au 16 Metal complex, 16 Au atoms in the structure of the metal complex form an Au 16 Macrocycle, 16 gold atoms form a polynuclear gold compound, and the chiral Au 16 Drug activity of the metal complex on cancer cells. In in-vitro cell experiments, the chiral Au 16 The metal complex has good in-vitro anticancer activity in different cancer cell lines. Meanwhile, due to the Au-Au bonding, a macrocycle structure is formed, and the chiral Au 16 Cytotoxicity of the metal complex on normal cells.

The invention discloses a preparation method of gold (I) albumin nanoparticles and application of the gold (I) albumin nanoparticles in antitumor activity. Belongs to the field of medicine, and the preparation method comprises the following steps: dissolving BSA in ultrapure water, titrating with N sodium hydroxide until the pH value is 8.5, dropwise adding an ethanol solution of a gold (I) compound, dropwise adding absolute ethyl alcohol, adding 8% glutaraldehyde, stirring, removing the free gold (I) compound and ethanol through dialysis, centrifuging for three times to obtain purified nano-particles, and drying to obtain the gold (I) compound. And freeze-drying to obtain the nanoparticle freeze-dried powder. According to the invention, the input ratio of BSA to the gold (I) compound is determined through preparation of the nanoparticles, the characterization of TEP NPs shows that the particle size has good stability, and the release behavior is shown under the pH condition close to the tumor microenvironment. The result shows that the TEP NPs can retain most of the gold (I) compounds in the nanoparticles, and after the nanoparticles are accumulated at the tumor site through the ERP effect, a large amount of the gold (I) compounds are released to achieve the tumor cell killing effect of the nanoparticles.

The present invention discloses phenanthroline-functionalized nitrogen heterocyclic carbene homonuclear and heteronuclear silver-gold compounds, methods, and applications. A binuclear N-heterocyclic carbene (NHC) silver complex (NHC-Ag2) and a heteronuclear NHC silver / gold bimetallic complex (NHC-Ag / Au) are synthesized using a phenanthroline-functionalized imidazole salt (HLPF6) ligand. NHC ligands have strong coordination ability and are easy to modify structurally, making them suitable for structural optimization of metal drugs. Heterocyclic functionalized NHC ligands are easy to construct multinuclear metal compounds, which can enhance the drug activity of metal drugs against cancer cells. The synthesized nitrogen heterocyclic carbene binuclear silver and heteronuclear silver / gold compounds have good in vitro anticancer activity in different cancer cell lines. Mechanism studies in colon cancer LoVo cells show that they cause increased intracellular reactive oxygen species and mitochondrial dysfunction, inducing cell necrosis.

The invention belongs to the technical field of fertilizers, and particularly relates to a multi-enzyme gold biological organic enzyme agricultural fertilizer. 8-12 parts of a mesoporous multienzyme gold compound, 10-15 parts of a temperature-sensitive enzyme nutrient compound, 3-5 parts of growth-promoting rhizobacteria microspheres, 62-76 parts of an organic carrier, 2-4 parts of a trace element additive and 1-2 parts of a pH buffer agent; wherein the mesoporous multienzyme gold compound is formed by compounding a functionalized silicon carbon carrier and a multienzyme gold compound according to a mass ratio of 1: 2; the temperature-sensitive enzyme nutrient compound is formed by compounding poly N-isopropylacrylamide, a biological organic enzyme and a slow-release nutrient according to a mass ratio of 2: 1: 3; the growth-promoting rhizobacteria microspheres are microspheres of a double-layer structure, and the growth-promoting rhizobacteria microspheres comprise the following components in parts by weight: 45-55 parts of an inner-layer bacterial strain protection layer and 45-55 parts of an outer-layer bacteriostatic protection layer.

The invention belongs to the field of organic synthesis, and particularly relates to an N-heterocyclic carbene gold compound and a preparation method and application thereof.The preparation method comprises the steps that an intermediate II is prepared, and after the intermediate II, a compound X and alkali are mixed and dissolved, an esterification reaction is conducted to generate an intermediate III; and fully mixing the intermediate III with an inorganic silver reagent, then adding an organic gold reagent and potassium salt, carrying out gold ion coordination reaction, and after the reaction is completed, carrying out post-treatment, separation and purification to obtain the product. The N-heterocyclic carbene gold compound disclosed by the invention has an anti-tumor immune effect and an anti-ferroptosis effect, and has a liver cancer specific targeting capability.

The invention belongs to the technical field of N-heterocyclic carbene gold compounds, relates to a double-pharmacophore N-heterocyclic carbene gold compound 1-14 and application thereof, and discloses a specific structure of the double-pharmacophore N-heterocyclic carbene gold compound 1-14, and the double-pharmacophore N-heterocyclic carbene gold compound 1-14 is prepared by replacing a triethyl phosphine group in gold nofen with NHC, and then adding a compound 1-14 and a compound 2-14, so that the double-pharmacophore N-heterocyclic carbene gold compound 1-14 is obtained. A traditional Chinese medicine micromolecule ferulic acid Fa is introduced for synthesis; the invention discloses application of double-pharmacophore N-heterocyclic carbene gold compounds 1-14 in preparation of anti-hepatoma drugs. The double-pharmacophore N-heterocyclic carbene gold compound Fa-Au has anti-proliferative activity on liver cancer cells HepG2 and Hepa 1-6, obviously inhibits the growth of tumors in a mouse, and improves the tumor immune microenvironment of the mouse at the same time; the N-heterocyclic carbene gold-ferulic acid compound has the advantages of reliable curative effect, no toxic or side effect, simple preparation, low price and the like.

A method for producing a catalyst for vinyl acetate production comprising a carrier, copper, palladium, gold, and an acetic acid salt, the method comprising, in the following order, step 1, in which an alkali solution is infiltrated into the carrier, step 2, in which the carrier is brought into contact and impregnated with a solution in which a copper-containing compound, a palladium-containing compound, and a gold-containing compound are contained in excess with respect to desired deposition amounts of the catalyst components, step 3, in which, after the catalyst components have been deposited in the desired deposition amounts, the carrier is separated from the solution, step 4, in which the carrier is brought into contact with water or an aqueous solution each having a pH of 7.0-11.5, step 5, in which a reduction treatment is conducted, and step 6, in which the acetic acid salt is deposited on the carrier.

The presently-disclosed subject matter includes useful water-soluble gold containing compounds and compositions, and methods of making and methods of using such compounds and compositions.

The present application relates to the field of precious metal recovery, and specifically discloses a method for recovering gold from gold ion electrolysis tail liquid; a method for recovering gold from gold ion electrolysis tail liquid, comprising the following specific steps: S1 ion exchange adsorption: after cleaning the mixed bed, soaking the ion exchange resin in sodium hydroxide solution, then loading it into the mixed bed and adding the gold tail liquid for ion exchange adsorption; S2 gold recovery: drying and carbonizing the ion exchange resin that has adsorbed the gold tail liquid to obtain a gold-containing compound, mixing and dissolving the gold-containing compound with aqua regia, using hydrochloric acid for denitrification to obtain gold aqua regia, vacuum filtering and washing, and then using anhydrous sodium sulfite for reduction to obtain reduced gold powder, which is then dried to obtain the gold powder; the ion exchange resin raw materials include cation exchange resin and carboxymethyl chitosan; the present application can enhance the adsorption capacity and adsorption rate of the ion exchange resin through the synergistic effect of various processes, thereby improving the gold recovery effect.

The present invention relates to a catalyst for preparing vinyl acetate and a preparation method therefor, and the use thereof. The preparation method comprises the following steps: kneading, drying, and shaping an ultrafine silica gel powder, ultrafine diatomaceous earth, a silica sol, and a boron compound at a weight ratio of 100: (5-20): (10-60): (0.1-1), followed by calcination at 150-650ºC for 1-6 h to prepare a boron-doped composite SiO2 carrier; subjecting the carrier to incipient wetness impregnation with rolling with a solution of palladium and gold compounds at a Pd / (Au+Pd) molar ratio of 0.76-0.93 and a loading amount of 0.5%-1% relative to the carrier mass, followed by drying; treatment with an alkaline solution for 0.5-30 h, then drying, and reduction at 300-650ºC in a nitrogen-hydrogen atmosphere for 1-6 h, and washing same with water until chlorine-free, followed by drying; preparing a dilute sol by mixing copper acetate and cesium oxide at a Cu / (Re+Cu) molar ratio of 0.93-0.97 and a loading amount of 0.3%-1% with 0.5%-3% aluminum phosphate, followed by dip coating and drying; impregnating with a potassium acetate solution at a loading amount of 0.2%-7.5%, and performing a heat treatment at a negative pressure at 60-200ºC for 1-6 h, to obtain a highly stable, long-life catalyst, which has high strength and few by-products.