47 results about "Scar revision" patented technology

The invention relates to a self-adhesive gel and a preparation method and application thereof in scar repair, the self-adhesive gel comprises germanene, polydimethylsiloxane, polyvinylpyrrolidone, triamcinolone acetonide, absolute ethyl alcohol and water, when the self-adhesive gel is used, ethyl alcohol and water in the self-adhesive gel can be rapidly volatilized to form a layer of self-adhesive polymer film, the self-adhesive polymer film is firmly adsorbed on the tissue surface, and the self-adhesive gel can be used for repairing scars. Meanwhile, polydimethylsiloxane can retain water, germanene has a photo-thermal effect and is beneficial to promoting diffusion and absorption of triamcinolone acetonide to tissues, and the self-adhesive gel can be used for preparing scar repair medicaments.

The invention discloses a repair liquid matching method based on skin scar repair. The method comprises the following steps: S1, acquiring a skin type, a scar type, a scar area and scar depth information of a user; s2, establishing a repair liquid database for each factor of the skin of the user; s3, performing weighted calculation to obtain the scar with the highest repair priority in all scars of the skin of the user; and S4, selecting the repair liquid with the highest conformity as matching output. Weighted calculation is carried out on the skin type, the scar type, the scar area and the scar depth information of the user, and the scar with the highest repair priority in all scars of the skin of the user is obtained; according to the method, the factor with the highest repair priority, the previous treatment data and the same type of treatment data are used as factors to compare the repair liquid database, the repair liquid with the highest conformity is selected as matching output, a personalized scar repair scheme can be provided according to specific conditions of different patients, and therefore the scar repair effect is improved.

The invention relates to the technical field of medical dressings, and discloses a scar repair gel containing recombinant mussel mucin and a preparation method thereof. The scar repair gel is prepared from the following components in percentage by mass: 0.01 to 0.2 percent of recombinant mussel mucin, 0.4 to 0.8 percent of a thickening agent, 6 to 15 percent of a compound emulsifier, 1 to 2 percent of a pH regulator, 20 to 40 percent of silicone, 0.1 to 0.3 percent of a preservative and the balance of water, wherein the silicone comprises polydimethylsiloxane, a polydimethylsiloxane cross-linking agent and decamethylcyclopentasiloxane. The scar repair gel containing the recombinant mussel mucin has good film-forming property, forms a moisturizing barrier on the surface of a wound, can inhibit formation of hyperplasia scars, reduces pruritus in the wound healing process, reduces generation and deposition of melanin, and has the effects of repairing scars and repairing scars. The comfort of a patient in the use process and the compounding stability of the mussel mucin and silicone gel system are effectively improved.

This invention discloses a thermosensitive material, a temperature-responsive nanofiber membrane, a preparation method, and applications. The thermosensitive material of this invention is shown in formula (Ⅰ). The thermosensitive material of this invention has a wide phase transition temperature, broadening its application range. The temperature-responsive nanofiber membrane of this invention possesses antibacterial, hemostatic, scar repair, and temperature-responsive contraction functions. It can exert an antibacterial effect in the early stage of wound healing and significantly help wound contraction, rapidly transitioning to the wound repair stage. During the scar formation stage, it reduces collagen deposition, ultimately forming a fully closed and mature scar-free healing zone.

The invention discloses a multi-effect compound scar-removing gel for repairing sensitive muscle scars and a preparation method of the multi-effect compound scar-removing gel, and belongs to the technical field of preparation of medical preparations for skin. The multi-effect compound scar-removing gel is prepared from the following raw materials in percentage by weight: 0.05 percent to 0.08 percent of recombinant III type humanized collagen, 0.63 percent to 0.66 percent of carbomer, 0.18 percent to 0.21 percent of sodium phosphosilicate calcium, 0.09 percent to 0.11 percent of gamma-polyglutamic acid, 1.6 percent to 2.2 percent of levodopa-amino silicon oil mixed liquid, 0.8 percent to 1.1 percent of oxidized ganoderma lucidum polysaccharide and the balance of deionized water. The preparation method comprises the following steps: mixing and dispersing recombinant III-type humanized collagen, carbomer, calcium sodium phosphosilicate, polyglutamic acid, a levodopa-amino silicon oil mixed solution, oxidized ganoderan and deionized water to form a dispersion solution; then, the dispersion liquid is adjusted to be in a weakly alkaline environment for cross-linking and then is adjusted to be neutral for standing and gelation, and the obtained multi-effect compound scar-removing gel is effective and good in scar repair and does not have a red and swollen irritation phenomenon.

1. Name of the design product: Packaging box (packaging box for scar repair gel). 2. Use of the design product: To package scar repair gel. 3. Design key points of the design: The pattern on the outer packaging of the product. 4. Picture or photograph that best shows the design key points: Front view. 5. The claimed design includes color.

The invention discloses medical silicone gel for scar repair and a preparation method and application thereof, and relates to the technical field of medical gel. The aloe polysaccharide silicone gel mask comprises the following raw materials in percentage by mass: 25-45% of aloe polysaccharide silicone gel, 1-2% of sodium hyaluronate, 0.2-0.8% of poly-L-lactic acid, 2-4% of vitamin E, 5-8% of asiaticoside, 1-3% of resveratrol, 1-2% of curcumin, 1-2% of hydroquinone, 2-4% of arbutin, 2-4% of a vitamin C derivative, 3-5% of a traditional Chinese medicine composition, 0.5-1.5% of an odor regulator, 0.1-0.3% of a preservative and the balance of water. And the balance of purified water. The smell regulator is a pH response release type adsorbent. The medical silicone gel not only can effectively repair scars, but also is good in skin feeling and not prone to sensitivity.

The invention belongs to the technical field of injectors, and particularly relates to a colloid squeezer for scar repair, which comprises two groups of telescopic components, an adjusting component, two groups of pressing components and a discharging component, the tops of the two telescopic assemblies are slidably connected with the bottom of the adjusting assembly, and the two pressing assemblies are slidably connected to the adjusting assembly. The two telescopic assemblies are used for being adjusted to different lengths to meet the requirement for scar cream of different sizes, one end of the scar cream is in butt joint with the discharging assembly, the other end of the scar cream is in press fit connection with the two pressing assemblies, the adjusting assembly drives the pressing assemblies to slide in the radial direction of the telescopic assemblies, and in the process that the adjusting assembly gets close to the discharging assembly, the scar cream can be discharged. The device is used for injecting the scar repair cream, so that the compatible combination use of the scar repair cream with different models and sizes is improved, the use range of the injector is widened, and the injection effect of the injector is improved.

The utility model discloses a tension-reducing scar repairing seam forming tool which comprises an elastic sterile transparent adhesive tape, a sawtooth strip is arranged on the elastic sterile transparent adhesive tape, release paper is arranged on the lower side of the elastic sterile transparent adhesive tape, sterile adhesive tapes are arranged on the two sides of the release paper, and an elastic strip is arranged at the edge position between the sterile adhesive tapes. Through the arrangement of the sawtooth strip, the elastic sterile transparent adhesive tape and the release paper, the release paper and the elastic sterile transparent adhesive tape are cut open from the middle, the elastic sterile transparent adhesive tape with the sawtooth strip is uncovered and then pasted on the annular side of the periphery of a scar, the sawtooth strip is an inkpad strip made of edible pigment, and after the inkpad is pasted on the skin, the elastic sterile transparent adhesive tape with the sawtooth strip is pasted on the skin. The shape of the sawtooth strip can be printed on the skin, the elastic sterile transparent adhesive tape is removed after the sawtooth strip is firmly adhered, and then the skin is treated according to the trace of the sawtooth strip, so that the marking operation step is simplified, and the operation efficiency is improved.

The application discloses a medical silicone gel for scar repair and a preparation method and application thereof, and belongs to the technical field of biomedical materials and tissue engineering. The medical silicone gel comprises the following components in percentage by mass: cyclic siloxane 1-10%, silicone 30-50%, polysiloxane polymer 10-30%, gel matrix 1-10%, and the balance is water. The silicone gel provided by the application is stable in property, has no cytotoxicity, has no skin irritation, is easy to spread, has good film forming property, has strong adhesion to skin tissue, has a tension reducing and pressure adding effect on scars, and has a better scar repair effect than that of a commercial product.

The invention provides a polypeptide PN-VW22 and application thereof, and belongs to the technical field of polypeptide drugs. The polypeptide PN-VW22 provided by the invention is specifically as follows A1) or A2): A1) an amino acid sequence as shown in SEQ ID NO.1; a2) a fusion protein obtained by connecting a label to the N end or / and C end of A1). The polypeptide has obvious cell proliferation activity and anti-staphylococcus aureus bifunctional activity, and also has a wound repairing effect. The polypeptide is small in molecular weight and stable in structure, can be industrially produced through solid-phase chemical synthesis, can also be industrially applied to preparation of treatment medicines for promoting skin wound repair, and can be used as a candidate polypeptide medicine or a medical beauty product raw material for treating body surface wounds, repairing tissues, burns and skin ulcers, reducing scars and accelerating scar repair.

The utility model belongs to the field of skin scar repair, and particularly relates to a skin scar repair drug delivery device which comprises a placing table and an operating cylinder, the operating cylinder is provided with an external thread connecting cylinder, the external thread connecting cylinder is provided with a button cover, the button cover is provided with a drug delivery paster, and the drug delivery paster is provided with a miniature puncture needle. The external thread connecting cylinder is provided with an elastic film and a liquid medicine permeation sheet. The operation cylinder is provided with an air cylinder, the air cylinder is provided with a piston rod, the piston rod is provided with a protective shell, the protective shell is provided with an operation motor, the operation motor is provided with a rotating rod, the rotating rod is provided with a massage rubber ball, and the operation cylinder is provided with a control switch. According to the skin scar repair drug delivery device, through cooperation of the massage rubber ball and the micro puncture needle, the problems that according to an existing penetration drug delivery device, the needle needs to be punctured into a scar many times, the pain feeling is high, drug delivery penetration is not uniform, the auxiliary massage absorption effect is poor, and meanwhile the manual operation cost is high are solved.

The invention discloses an in-situ cross-linked silicone elastomer for scar repair and a preparation method thereof.The silicone elastomer is prepared by mixing a component A with vinyl polysiloxane and a moisture absorbent as main components and a component B with polyhydrosilane as a main component and then coating the surface of skin with the mixture, under the action of a catalyst, in-situ polymerization and crosslinking are carried out on the skin surface. The preparation method comprises the following steps: firstly, respectively preparing a component A containing vinyl polysiloxane, a moisture absorbent and the like and a component B containing polysilazane; respectively filling the component A and the component B into different containers, uniformly mixing by a static mixer according to a certain proportion, and uniformly smearing the mixture on a skin scar; and standing and curing at normal temperature to form the silicone elastomer at the skin scar. The adhesive provided by the invention has the advantages of good adhesive property, convenient coating property, hygroscopicity, moisture retention, stability, lowest skin irritation, good fitness and few residues.

The invention belongs to the technical field of medical dressings, and particularly relates to a sunken scar repair dressing and a preparation method thereof. The concave scar repair dressing comprises a hydrophilic fiber layer, a hydrophobic barrier layer and a biological active layer which are sequentially arranged from the side in contact with a wound surface to the outside, the hydrophobic barrier layer is partially combined on the surface of the hydrophilic fiber layer in a physical embedding manner, and the bioactive layer is fixed on the outer side of the hydrophobic barrier layer in a chemical crosslinking manner; the hydrophilic fiber layer is composed of polyvinyl alcohol / hyaluronic acid composite fibers prepared through electrostatic spinning. The three-layer structure of the dressing simulates partial functional gradient of the skin, covers hydrophilic absorption, barrier protection and active repair, and better meets physiological repair requirements. According to the invention, interlayer combination is realized through two mechanisms of physical embedding and chemical crosslinking, so that the integrity and durability of the dressing are remarkably improved, and layering during use is avoided.

According to the silica gel scar patch and the preparation method, the silica gel scar patch has good antibacterial performance, anti-inflammatory performance and relieving performance, bacterium breeding of the scar part can be effectively inhibited, the infection risk is reduced, cleaning and healing of scars are promoted, uncomfortable symptoms such as pruritus and pain of the scar part are relieved, and the silica gel scar patch has the good application prospect. And the use comfort of the patient is improved. In addition, the silica gel scar patch also has good elasticity, can stretch and deform along with the movement of the skin, does not cause oppression or discomfort to the skin, and is suitable for scars of various parts. The silica gel scar patch has excellent air permeability and comfort level, can effectively promote scar repair, improve scar appearance and relieve scar itching, pain and other symptoms, and is suitable for various types of scars such as operation scars, burn scars and wound scars.

The present invention relates to a topical skin composition effective in promoting wound healing and / or scar repair, comprising (A) concentrated birch sap and (B) one or more active substances selected from burnet root extract, coptis root extract, lilac extract, allantoin, red sage extract, astragalus extract, pearl powder, and asiaticoside, wherein the concentrated birch sap is concentrated by about 1.2 to 6 times, preferably about 1.5 to 5 times, and more preferably about 1.5 to 3 times.

Herein disclosed is a device operable to perforate a skin, the device comprising: a housing comprising an upper member and a bottom member, wherein the upper member is detachably engaged to the bottom member; an actuation mechanism housed proximal to the upper member; a biasing member operably coupled to the actuation mechanism; one or more striking members; and more than one blades, each of the more than one blades operably coupled to a corresponding striking member of the one or more striking members, wherein the biasing member is operable to have the actuation mechanism activate an actuating member to drive each of the one or more striking members in a manner which renders each of the more than one blades to perforate the skin.

The invention discloses an exosome purification method, a prepared exosome and application. The method comprises the following steps: firstly, forming a crude exosome by utilizing the charged difference of substances such as exosome, impure protein and endotoxin and adopting an acid-base precipitation and ultrafiltration combined technology; then fine purification is performed by adopting a composite chromatography method, impurities are efficiently removed, and the high-purity exosome is rapidly obtained. According to the method, the defects of long time consumption, more impurities, small treatment capacity and incomplete protein removal of the traditional method are overcome, and low-cost and high-yield high-purity exosome production is realized. The obtained exosome significantly promotes cell migration, especially human fibroblasts, has positive effects on cell repair and skin wound healing, has the potential of being applied to the field of cosmetics and accelerating epidermis inflammation and scar repair, and promotes commercialized application of high-purity exosome.

The invention discloses a scar repair patch containing tacrolimus and a preparation method of the scar repair patch, and belongs to the technical field of medical dressings. The patch comprises a backing layer, a medicine storage and release layer and a protective film layer. The medicine storage and release layer is composed of a hydrogel matrix and tacrolimus, and the mass percent of tacrolimus is 0.01%-0.1%. The hydrogel matrix comprises polyvinyl alcohol, glycerol, a cross-linking agent and purified water. The preparation method comprises the following steps: dissolving tacrolimus in ethanol to form a medicine solution; preparing a polyvinyl alcohol hydrogel matrix; and mixing the medicine solution with the matrix, coating the mixture on the backing layer, and performing radiation crosslinking curing, slitting, packaging and sterilization. The hydrogel is adopted as a drug carrier, the technical problems that tacrolimus is non-uniformly dispersed and difficult to release in silica gel are solved, and a novel medical instrument which is stable in drug release, good in biocompatibility and suitable for inhibiting scar hyperplasia for a long time is provided.

The invention relates to the field of skin repair articles, and discloses a scar repair composition and a preparation method thereof. The preparation method comprises the following steps: the additives including the emulsifier and the emollient are mixed and homogenized in water, grease in the additives is completely emulsified to obtain emulsified liquid, and the emulsifier comprises polyglycerol-10 dipalmitate, polyglycerol-6 distearate and potassium cetyl phosphate; uniformly mixing the skin repairing agent with the emulsion; the skin repairing agent comprises rice protein peptide, a water-soluble centella asiatica total glycoside extract, PDRN, vitamin B12 and a radix arnebiae extract. The scar repair composition has better stability and activity, and has a good effect on skin scar repair.

1. Name of the product in this design: Packaging Box (Postpartum Scar Repair Gel). 2. Purpose of this design: For use in product outer packaging boxes. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

1. The name of this design product: Packaging Kit (Medical Silicone Scar Repair Patch). 2. Purpose of this design product: used for product packaging. 3. The key design point of this design product lies in the pattern. 4. The image or photo that best illustrates the key design features: Kit 2 main view. 5. This design is a thin product, and the left view, right view, top view, and bottom view of Kit 1 are omitted. 6. Other situations that require explanation Other explanations: This design product is a kit product, so it is used and sold as a set. Kit 1 is the inner packaging bag, Kit 2 is the outer packaging box, and Kit 1 is placed in Kit 2 for sale and use.

The invention discloses a traditional Chinese medicine formula for softening hyperplasia scars and a preparation method thereof. The formula is composed of manis pentadactyla, salvia miltiorrhiza, safflower, leech, peach kernel, ligusticum wallichii, pseudo-ginseng, frankincense, myrrh, curcuma zedoary, rhizoma sparganii, golden head centipede, lucid ganoderma, quick lime, white mulberry root-bark, cocklebur fruit, wahlenbergia marginata, malva verticillata, sedum sarmentosum, mazus japonicus, selfheal, mature vinegar, alcohol and other medicinal materials. Through accurate proportioning and scientific preparation, the formula can effectively soften hyperplastic scars and promote repair and regeneration of skin tissues, and has the characteristics of mildness, no irritation and no obvious side effects. The preparation method comprises the steps of raw material preparation, material mixing, forming, preparation and the like. The traditional Chinese medicine composition has remarkable superiority in the aspects of softening scars, relieving pruritus and improving skin texture, is suitable for repairing various types of scars after operation, burn and the like, and has a wide application prospect.

The invention relates to the technical field of biological medicine, and discloses a preparation method for improving wound scar repair effect, which comprises the following steps: crushing dried periplaneta americana, and soaking with ethanol; then carrying out reflux extraction, filtration, concentration and drying to obtain a dried periplaneta americana insect extract; dissolving collagen and hyaluronic acid in glycerol, adding the dried periplaneta americana insect extract, uniformly stirring, and preparing a medicine storage layer; wherein the collagen accounts for 5% of the total amount, the hyaluronic acid accounts for 1% of the total amount, the glycerol accounts for 89% of the total amount, and the American cockroach dried insect extract accounts for 5% of the total amount. The medicine storage layer is arranged on the backing layer in a stepping mode and covered with the anti-sticking layer, so that the scar patch capable of improving the wound scar repairing effect is manufactured. According to the preparation method for improving the wound scar repair effect, wound healing is promoted, scar hyperplasia is inhibited, the anti-inflammatory effect can be achieved, the moisturizing effect is good, natural components are adopted, safety is high, and the scar repair effect is improved.

The invention belongs to the technical field of medical supplies, and discloses a scar repair patch with an immune microenvironment adjusting function and application thereof.The scar repair patch comprises a backing layer, a silica gel layer and a protective film layer, the silica gel layer is connected with the backing layer, the backing layer is connected with elastic cloth, and the elastic cloth is connected with a pasting layer; the silica gel layer is prepared from a first silica gel component, a second silica gel component and an immune regulation component, and the immune regulation component is prepared from the following raw materials in parts by mass: 2 to 8 parts of arginine hydrochloride, 0 to 10 parts of chondroitin sulfate, 20 to 35 parts of polyethylene glycol 400, 20 to 35 parts of polydimethylsiloxane, 20 to 35 parts of glycerol, 3 to 10 parts of cetyl PEG / PPG-10 / 1 polydimethylsiloxane and 4 to 10 parts of purified water; meanwhile, the preparation method is optimized, according to the technical scheme, immune cell phenotypes can be actively regulated and controlled, repairing and healing of skin wounds are synergistically promoted, closing of chronic wounds is accelerated, skin regeneration of acute wounds is promoted, scar growth is inhibited, the curative effect of the scar patch is improved, and long-term use of the scar patch is facilitated.

The invention relates to the technical field of medical dressings, in particular to a scar repair silicone gel and a preparation method thereof. The scar repairing silicone gel is prepared from the following components in percentage by mass: 10 to 20 percent of decamethylcyclopentasiloxane, 6 to 10 percent of organic silicon polymer, 2 to 7 percent of simethicone, 3 to 5 percent of functional additive, 0.3 to 0.6 percent of hydroxyethyl cellulose, 1 to 3 percent of glyceryl monostearate, 3 to 8 percent of glyceryl stearate, 1.5 to 2 percent of fumaric acid, 0.2 to 0.6 percent of ethylhexylglycerin and the balance of water. The linear polymethylhydrosiloxane is crosslinked to form a compact elastic three-dimensional network, so that the silicone film has excellent air permeability and mechanical properties; the functional auxiliary agent realizes dual repair of physical closed moisturizing and biological activity promotion, and is beneficial to repair of scars; the silicone gel prepared by the invention not only can efficiently repair scars, but also has excellent antibacterial property, mechanical property and biocompatibility, and the whole system does not contain irritant components and is suitable for sensitive skin.

The utility model belongs to the technical field of scar repair, and discloses an instrument for repairing scars caused by tattoo washing, which comprises a scar repair instrument body, a storage cavity is arranged in an inner cavity of the scar repair instrument body, a pressing rod is pressed through the arrangement of a cleaning mechanism and a clamping mechanism, so that the pressing rod drives a sliding block fixedly connected with the pressing rod to move downwards along a sliding rail; when the sliding block moves, the moving plate connected with the sliding block can be driven to move, the auxiliary rod connected with one end of the moving plate pulls the limiting plate connected with the auxiliary rod, meanwhile, the rotating plate rotationally connected with the other end of the moving plate can rotate around the rotating shaft, and then the other limiting plate is driven to correspondingly move. Finally, the distance between the two arc-shaped limiting plates capable of being spliced into a circle is increased, the repairing probe continues to be pushed inwards, the repairing probe can be wrapped by the cleaning cotton, and meanwhile the repairing probe can rotate through movement of the rotating block in the rotating groove in the moving process.

1. The name of the design product: erbium laser therapy instrument (Bifang-Aurora). 2. The use of the design product: for the treatment of epidermal nevus, wart, scar repair. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective drawing.

The utility model discloses a birthmark scar repair device, including repair instrument, repair instrument electrical connection on the power supply equipment, the repair instrument is provided with the indicating mechanism, the indicating mechanism includes bearing disc, repair head, telescopic sleeve, spring, spacing ring, laser lamp, push rod, follow-up mechanism and wire clamping mechanism, the bearing disc is installed on the repair instrument, the telescopic sleeve is installed on the bearing disc, and the spring is installed on the telescopic sleeve. The multiple repairing heads are installed on the bearing disc, the telescopic sleeve is slidably connected to the bearing disc, one end of the spring is connected to the telescopic sleeve, the indicating mechanism can accurately control the irradiation direction and position of the laser lamp, and accurate irradiation is achieved through combination of the bearing disc and the repairing heads. Due to the synergistic effect of the limiting ring and the spring, the stability of the repairing head in the operation process is ensured, and therefore the accuracy and safety of treatment are improved.

The invention discloses a device for oral corner malformation correction and scar repair after burn, and belongs to the technical field of medical instruments. The device comprises a fixing frame, a movable supporting column, an arc-shaped baffle and a repairing plate, the front end of the fixing frame drives a wedge-shaped pressing block through a lead screw to drive a slope sliding block to adjust the opening distance of the movable supporting column, and dynamic correction of the mouth angle is achieved; the arc-shaped baffle is provided with a laser head connecting hole and an adjustable repairing plate, and drug-containing repairing microneedles are distributed on the surface of the repairing plate. The device has the beneficial effects that precise control over the opening angle opening strength is achieved through the lead screw-inclined plane sliding block linkage mechanism, and excessive correction is avoided; laser treatment and microneedle administration are synchronously carried out, so that the scar repair efficiency is remarkably improved; the pressure detection module can adjust the correction force in real time, and the treatment safety is ensured.