40 results about "Scar revision" patented technology

The invention discloses an externally-applied skin-regenerated oily traditional Chinese medicament for treating various burns and scalds, relates to the technical field of Chinese medicine preparations, and particularly relates to an externally-applied oily traditional Chinese medicament for treating various burns and scalds, wounds, bacterial infection, eczema, psoriasis and old scar repair. The medicament is prepared from the following bulk pharmaceutical chemicals in parts by mass: 500-1000 parts of castor seed oil, 2-4 parts of pearl powder and 2-4 parts of notoginseng powder. The preparation method of the medicament comprises the following steps of: (1) selecting fresh castor seeds, obtaining castor seed oil by using a cold pressing method, placing the pressed castor seed oil into a stainless steel electric heating container, heating the castor seed oil to 60 DEG C, and cooling the castor seed oil for standby; (2) selecting pearls to be cleaned and disinfected, carrying out ultrafine microsphere grinding on the pearls by using a microsphere grinding machine so as to obtain pure pearl powder for standby; (3) selecting notoginseng, carrying out crushing and ultrafine microsphere grinding on the notoginseng so as to obtain notoginseng powder for standby; and (4) weighting the cooled castor seed oil in mass proportion, placing the weighted castor seed oil into a sterile medical glass bottle, weighting the pearl powder and the notoginseng powder, adding the powder into the castor seed oil, uniformly shaking the obtained mixture, and carrying out aseptic bottle-sealing on the obtained product.

The invention discloses a vilepofen-loaded microneedle for scar repair and a preparation method and application thereof. The vilepofen-loaded microneedle is prepared by mixing vilepofen into a hydrogel precursor solution, filling the gap of a microneedle template with the mixture, and removing the template after the solution is solidified. The loaded vilepofen can be slowly released from the microneedle; the needle tip of the microneedle is high in penetrability, and the permeability of vilepofen in a scar can be enhanced; the morphology of the needle tip can be adjusted according to the application environment of scar treatment; and the loading amount of vilepofen can be adjusted according to the severity of the scar.

The invention discloses a whitening cosmetic and a preparation method of the whitening cosmetic. The whitening cosmetic comprises the following raw materials by weight percent: 50-70wt% of cucumber seed oil, 15-25wt% of Hypericum perforatum oil and 15-25wt% of calendula oil. The preparation method of the whitening cosmetic comprises the following steps of: mixing 50-70wt% of cucumber seed oil, 15-25wt% of Hypericum perforatum oil and 15-25wt% of calendula oil at the temperature of 20-25DEG C, and evenly stirring to obtain a product. The whitening cosmetic disclosed by the invention is made from the natural plant oil, green, safe, and free of stimulation to the skin; the whitening cosmetic is discovered to be not only good in whitening effect, but also very good in effect for fading the chromatosis, repairing the sensitive skin, repairing the scar remained by pimples and whelk, i.e. acne marks, acne holes and the like after being tried out by 780 customers; the whitening cosmetic can refine the pores, and is good in effect for curing the sunburn and the skin light sensitivity; and the whitening cosmetic is free of anaphylaxis.

The invention discloses a thymosin β-4 ethosome and a preparation method thereof. The specific composition of the thymosin β-4 ethosome comprises: thymosin β-4 0.022%-0.043%, phospholipid 0.054%-0.084% , cholesterol 0.018% ~ 0.028%, anionic surfactant 0.02% ~ 0.04%, ethanol 10.10% ~ 30.30%, the rest is distilled water; it has the effect of increasing the transdermal absorption of drugs and enhancing the repair of scarred skin by thymosin β‑4 technical effect. And the preparation method of thymosin β-4 ethosome in the present invention, utilizes the mode that adds anionic surfactant and cholesterol to solve the stability problem of thymosin β-4 ethosome, adopts the thymosin that this preparation method obtains The β‑4 ethosome has high encapsulation efficiency, good stability, simple process and good economic benefits. Correspondingly, the present invention also protects the application of the thymosin β-4 ethosome in the field of scar repair.

The invention discloses a scar repair material and a preparation method thereof. It is made of microcapsules and cross-linked hyaluronic acid gel. The microcapsules use chitosan and hyaluronic acid Ketoin and allantoin are core materials, and the microcapsules are evenly dispersed in the cross-linked hyaluronic acid gel, and the chitosan substance is chitosan or / and chitosan derivatives, and the hyaluronic acid Substances are hyaluronic acid or / and hyaluronate. The scar repair material of the present invention is highly safe, and the microcapsules embedded with ectoine and allantoin can work continuously and stably in the cross-linked hyaluronic acid gel scaffold, have good biocompatibility, excellent Scar repair, healing promotion, anti-inflammation function, at the same time, the mechanical strength of the material is controllable, can be completely degraded, and has a wider range of applications.

The invention discloses a single-atom nano-enzyme patch used for skin wounds and a preparation method. Preparation: preparing Ce(NO 3 ) 3 ·6H 2 O water is solution one; preparation of 6-aminocaproic acid and concentrated hydrochloric acid water is solution two; concentrated ammonia water is added to solution one, stirred, added solution two, and reacted to obtain CeO 2 cluster and prepare an aqueous suspension, the polyvinylpyrrolidone and K 2 PtCl 4 added to water to obtain solution three; the CeO 2 The cluster water suspension was added to solution three, reacted, and then NaBH was added dropwise 4 Aqueous solution; reaction; obtain single-atom nanozyme, drop on activated hydrophilic carbon cloth; dry to obtain activated hydrophilic carbon cloth containing single-atom nanozyme; arrange activated hydrophilic carbon cloth containing single-atom nanozyme in sequence on the upper surface of the medical tape Carbon cloth and release paper to obtain a single-atom nanozyme patch for skin wounds. The patch of the invention can significantly promote wound healing, scar repair and hair regeneration in the later period, and has no toxic and side effects.

Scar revision ointment is characterized by being made from materials by weight, namely g / part. A making method of the scar revision ointment includes: making 200-1000 parts of ginseng, 300-1200 parts of root of red-rooted salvia, 250-1200 parts of astragalus root, 100-700 parts of safflower, 200-1000 parts of palmleaf raspberry fruit, 200-1000 parts of cassia seed, 300-1200 parts of madeiravine bulbil, 300-1200 parts of pseudo-ginseng, 70-500 parts of dried ginger and 50-500 parts of Szechuan lovage rhizome into concentrated thick extract; blending 100-600 parts of frankincense and 100-600 parts of myrrh; grinding 40-100 parts of camphor powder and 20-80 parts of menthol and melting; making accessories, namely 300-1000 parts of stearic acid, 500-2000 parts of lanolin, 500-2000 parts of yellow soft paraffin and 100-500 parts of sorbitol into emulsifiable paste; dissolving 200-500 parts of sodium carboxymethylcellulose in distilled water; mixing the prepared accessories in a water bath, mixing and holding the temperature at about 40 DEG C for 9 hours to make the scar revision ointment; storing in airtight place for three months, opening containers, mixing well again, and filling and sealing. Over two hound clinical cases show that all scars can be revised to skin in normal conditions and normally functional. The revised skin is functional in perspiration, hair normally grows, and both the vessels and the nervous system can be restored to normal level.

The present invention provides a method for inducing human skin fibroblasts to differentiate into adipocytes in vitro, the method comprising: A. In vitro culture and passage of human skin fibroblasts in a basal medium, and when the cell confluence reaches 80- 100%, carry out induced differentiation; B. Replace the basal medium of step A with induced differentiation medium ①, cultivate for 6-10 days, and change the medium every two days; then, replace induced differentiation medium ① with induced differentiation Medium ②, cultured for 2-4 days; finally changed to basal medium, cultured for 8-14 days, and changed the medium every two days. The invention successfully solves the problem of inducing and differentiating human skin fibroblasts into adipocytes; by inducing the skin fibroblasts to differentiate into adipocytes, the scars left by the skin during wound healing are reduced, and the scars left by the skin during wound healing are reduced, which is a good solution for clinical wound repair and treatment. Scar repair, etc. provide new ideas and new treatments.