The invention discloses a processing method of medicinal fermented mass particles. The processing method comprises the following steps: taking and mixing the medicinal materials of 6.6g of polygonum flaccidum, 4.0g of bitter apricot seeds, 9.0g of hawthorns (fried), 6.0g of rhizoma atractylodis, 3.0g of angelica dahurica, 6.0g of purple perilla, 1.5g of cinnamomum cassia, 21.2g of wheat bran, 6.6g of xanthium sibiricum, 4.0g of rice beans, 6.0g of dried orange peel, 3.0g of cortex magnoliae officinalis, 3.0g of areca seeds, 3.0g of mint, 6.0g of nutgrass galingale rhizomes, 6.6g of southernwood, 9.0g of malt, 6.0g of pogostemon cablin, 3.0g of radix vladimiriae, 3.0g of fructus aurantii (stir-fried with bran ), 9.0g of millet sprouts, 1.5g of glycyrrhiza uralensis and 21.2g of wheat bran; under the low temperature of 20-30 DEG C, crushing the medicinal materials into fine powder, and screening the fine powder; taking 10.6g of flour, uniformly mixing the flour and the finest powder, and then placing the mixture in a sealed room; under the environment that the temperature is 30-35 DEG C and the humidity is 85-90%, performing fermentation until white mold is generated wholly and bouquet is generated, and taking and drying the fermented mixture so as to obtain the medicinal fermented mass particles. The medicinal fermented mass particles can be directly taken after mixing with water without being crushed or decocted, so that the difficulty of taking the medicine is reduced; when the medicine is taken, decocting the particles is not needed, so that the loss of the effective components in the medicine is reduced, and besides, in the preparation technology, the medicinal materials are crushed into the finest powder, so that the utilization rate of the medicine is increased, and the release of the medicine and the absorption of the medicine for a human body are facilitated.