The invention discloses a method for realizing shift photography and three-dimensional multi-region automatic focusing through touch screen operation. The method for realizing the shift photography and the three-dimensional multi-region automatic focusing through the touch screen operation includes the following steps: A, using a camera lens to gather an image of a shot object, converting into an electric signal through an image sensor, and displaying on a touch display screen; B, enabling an operator to choose a focus point through the touch screen; C, enabling the camera lens to automatically choose an offset direction, or enabling the operator finger to slide on the touch screen to indicate a camera lens deflecting direction; D, automatically focusing in Z-axis; E, automatically focusing in Rx-axis and Ry-axis. Through operating on the touchpad, the method for realizing the shift photography and the three-dimensional multi-region automatic focusing realizes the three-dimensional automatic focusing in different depths of fields selected by the operator on the touch screen through controlling the move of the camera lens according to the chose interested object region, and moreover, the method realizes the automatic focusing for the interested object region through choosing on the touch screen, and the focusing is more convenient to realize, is more precise, does not need training, and is more interesting and so on.