295 results about "Thianaphthene" patented technology

The invention discloses phosphorescent luminescent materials and a preparation method and application thereof. The invention is characterized in that the phosphorescent luminescent materials are red light materials containing a metal iridium complex; a structural general formula of the phosphorescent luminescent materials is shown in the specification; and in the structural general formula, R1 and R2 are independently one of alkyl, phenyl, halogen-substituted phenyl, alkyl-substituted phenyl, naphthyl, anthryl, a halogen substituent, methoxy, phenoxy, cyano-substituted carbazolyl, substituted N-phenylcarbazolyl, quinolyl, thiazolyl, thienyl, an aromatic amino group, a group with an azole structure, an aromatic heterocyclic radical, a substituted aromatic heterocyclic radical and a silicon alkyl substituent respectively. The phosphorescent materials have high luminous efficiency; and the high luminous efficiency shows that the compounds can be taken as luminescent materials or main luminescent materials and applied to electroluminescent devices. Through data test and comparison, the materials are organic electroluminescent materials which have excellent performance and a good prospect, and particularly are phosphorescent red light materials which have good performance; and moreover, a method for synthesizing the luminescent materials is simple and low in cost.

The present invention is directed to a compound of general formula (I),wherein R<1 >is selected from phenyl, pyridinyl, thiophenyl, furanyl, imidazolyl; each phenyl ring and heteroaromatic ring optionally and independently being further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo, as well as their pharmaceutically acceptable salts. The invention includes pharmaceutical compositions comprising these compounds and the use of the compounds in therapy, in particular in the management of pain.

Heterocyclic compound represented by the formula Iwhereinrepresentsor the like; R1 represents hydrogen atom, C1–C6 alkyl or benzyloxy; R2 represents methyl or nil; R3 represents hydrogen atom, C1–C6 alkyl, C2–C6 alkenyl, C3–C8 cycloalkyl or —CH2R5 [wherein R5 represents phenyl (which may be substituted with C1–C6 alkyl, halogen atom or cyano)] or thienyl; R4 represents C1–C6 alkyl, C2–C6 alkenyl, C3–C8 cycloalkyl or —CH2R6 [wherein R6 represents phenyl (which may be substituted with C1–C6 alkyl, halogen atom or cyano), naphtyl or thienyl]; or R3 is coupled with R4.

The invention relates to thiophene derivatives of formula (I) / their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.

A compound of Formula (I): wherein:R1 is C1-6 alkyl, benzyl, or (CH2)n—C(O)NH2; wherein the benzyl may be unsubstituted or substituted by one or two C1-6 alkyl, halogen, C1-6 alkoxy, or methylenedioxy groups;R2 is benzimidazolyl, quinolinyl, benzofuranyl, napthyl, indolyl, benzothiophenyl, phenyl, furanyl, thienyl, or pyridyl substituted or unsubstituted by one, two or three halogen, C1-3 alkyl, C1-3 alkoxy, or methylenedioxy groups;X1 and X2 are independently hydrogen, halogen, C1-3 alkyl, C1-3 alkoxy, nitro, CF3, or CN;n is 1, 2, or 3;m is 1, 2 or 3;or a pharmaceutically acceptable salt thereof.

This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.

The invention discloses a thienyl polymer-containing photocatalyst with high photocatalytic water splitting hydrogen production activity and a preparation method thereof. The photocatalyst is prepared by adopting a simple ternary copolymerization Suzuki coupling reaction, and the construction unit of the photocatalyst comprises pyrene, thiophene or thiophene derivative and dibenzothiophene sulfone. The pyrenyl monomer and the dibenzothiophene sulfuryl monomer for polymerization have the same polymerizable functional groups and can be subjected to Suzuki coupling reaction with thiophene or thiophene derivative monomers at the same time so as to ensure that pyrenyl units and dibenzothiophene sulfuryl units in the polymer structure are connected through thiophene or thiophene derivative units. The polymer photocatalyst has the characteristics of high photocatalytic hydrogen production activity, high apparent quantum efficiency, narrow optical band gap and continuous and adjustable structure and composition, is simple in preparation process, high in yield and stable in performance, can release hydrogen under sunlight, and can be used in the field of photocatalytic hydrogen production.

The invention discloses a carbonyl reductase derived from Rhodosporidium toruloides ZJB14212, a gene, a vector, a strain and an application of the carbonyl reductase in the preparation of chiral drug intermediates. The above carbonyl reductase can biologically catalyze preparation of highly optically pure (S)-N,N-dimethyl-3-hydroxy-3-(2-thienyl)propionamide, (S)-N-methyl-3-hydroxy-3-(2-thienyl)propionamide, (R)-3-chloro-1-(2-thienyl)1-propanol, ethyl (S)-3-hydroxy-3-(2-thienyl)propanoate, (S)-3-hydroxy-3-(2-thienyl)propionitrile, tert-butyl 6-chloro-(3R,5S)-dihydroxyhexanoate, (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxyvaleryl]-4-phenyl-1,3-oxazolidine-2-one and methyl [S-(E)]-2-[3-[3-[2-(7-chloro-2-quinolyl)vinyl]phenyl]-3-hydroxypropyl]benzoate.