37results about How to "Embolization effect is good" patented technology

A spring ring is formed by connecting at least four basic units on different planes. The at least four basic units comprises at least two c-shaped units and at least one o-shaped unit or omega-shapedunit, and the at least two C-shaped units are arranged on two adjacent planes and are sequentially connected to form an S-shaped structure. The embolism device preferably comprises a plurality of spring rings arranged side by side, the plurality of spring rings are connected end to end and one of any adjacent two spring rings is capable of twisting relative to the other about the axis of the embolism device. Because the stability of the omega-shaped structure is good, the stability of the spring ring can be maintained. Meanwhile, because a three-dimensional S-shaped structure has good turningcapability, the spring ring has better compliance. According to the construction mode, the spring ring can simultaneously meet the requirements of stable basket forming and compliant filling, therebybeing beneficial for the spring ring to conform to aneurysms with different shapes and sizes, and obtaining a better dense packing effect.

The invention provides bullet-shaped non-spherical microparticles and microcapsules. The matrix of the microparticles and microcapsules is polymerized photopolymerizable polymer. The tails of the microcapsules are smooth and connected, and the microcapsules have at least one mutually independent chamber, and the chamber contains an oil phase solution. The present invention also provides a method for continuously preparing the bullet-shaped non-spherical microparticles and microcapsules by using microfluidic technology. The technical solution of the present invention can improve the flow characteristics and movement speed of microparticles and microcapsules in channels, and improve the embolization effect of microparticles and microcapsules. The microcapsules provided by the present invention can realize the entrapment and transmission of active substances such as drugs.

The invention discloses a developing embolic material and a preparation method of the developing embolic material. Developable barium-alginate embolic microspheres encapsulating in-situ synthesis barium sulfate particles are prepared from one step by the adoption of an electrostatic spraying technology, integration of a developing agent and the embolic material is achieved, and the problems that when interventional therapy is clinically adopted, indirect developing exists and rechecking is difficult are solved. The mono-dispersion microspheres with the grain diameter being 100-1000 microns can be obtained by adjusting and controlling the electrostatic spraying parameter, so that the mono-dispersion microspheres with the grain diameter being 100-1000 microns are suitable for embolism of vessels of different calibers. The development agent, barium sulfate, and the barium-alginate microspheres are formed at the same time, and the barium sulfate particles are evenly distributed in the microspheres and firmly fixed. Extracorporeal simulation experiments prove that the developing microspheres are quite stable within the testing time of 50 days. A big-eared rabbit right kidney arterial embolism experiment proves that the developing microspheres have a good developing effect and an embolic effect. Because the electrostatic spraying technology has the characteristics of being simple, rapid and low in cost, the one-step preparation method has the production potential.

A composition comprising porous silica particles of the present invention has a modified surface which inhibits clotting and precipitation in blood, thereby effectively delivering physiologically active ingredients to target tissue or cells in the bloodstream. Also, in addition to the above advantage, a composition for an embolization procedure comprising porous silica particles of the present invention has the advantages of having biodegradability and sustained release properties such that excellent embolization effects may be obtained, and having excellent targeting properties for tumor tissue or cells and thereby causes few side effects.

The invention discloses a preparation method of magnetic induction hyperthermia embolism microspheres. The preparation method comprises the following steps of by taking a dissolved matter obtained bydissolving biodegradable high molecular polymers with low transition temperature and super paramagnetic Fe3O4 nano-particles into dichloromethane as an oil phase, Span 80 as a surfactant and an aqueous solution dissolved with polyvinyl alcohol (PVA) as an internal water phase, dropwise adding a water phase in the oil phase under the conditions with low temperature and high shearing to form primaryemulsion; placing the primary emulsion in a membrane emulsification instrument for membrane emulsification under the low temperature condition; forming multiple emulsion in a continuous phase of an external water phase PVA after the primary emulsion permeates a membrane, and performing low-temperature solidification to obtain the magnetic induction hyperthermia embolism microspheres which meet the demand for clinic size. The obtained microspheres are arbitrarily adjustable in size in a range from 100 microns to 1000 microns, can realize rabbit orthotopic liver cancer model embolism hyperthermia under guidance of iconography and have potential application in the interventional hyperthermia field of orthotopic tumors.

The invention relates to a suspension of Fe#-[3]O#-[4] microparticle and iodized oil for treating liver and kidney tumor by embolizing and its preparation process, wherein the suspension wherein the suspension is prepared by fully mixing 50um-300um Fe3O4 particles with non-limited specification and iodized oil by the proportion of 85-110mg : 1ml.

This invention relates to a Chinese traditional medicinal embolus for treatment of hyperthyroidism. The embolus is composed by the following ingredients by weight / share: common bletolla tiber glue(10.0), coptis rhizome, lyophilized powder injection(1.8), distilled water(100) and common bletolla tiber stalk piece(22.0).The medical embolus not only has good curative effect of embolizing but also has the curative actions of anti-infection, hemostasis, analgesia etc.