The invention discloses a
nutritional composition for
fatty liver and liver protection and a preparation method thereof, and relates to the technical field of nutritional health-care product preparation. The preparation method comprises the following steps: mixing fat-soluble components such as an
elephantopus scaber
alcohol extract with hydroxylated modified soybean
phospholipid, and adding absolute ethyl
alcohol to prepare a hydrophobic phase solution; deionized water is added into water-soluble components such as the walnut
oligopeptide to prepare a hydrophilic phase solution; dropwise adding the hydrophobic phase solution into the hydrophilic phase solution, and performing high-shear stirring, intermittent
ultrasonic emulsification, curing and
spray drying to prepare a nano composite carrier; mixing with hippocampal
peptide and ganoderan, and constructing a gradient release structure through double-layer hydroxypropyl
methyl cellulose coating; and finally adding the remaining components and mixing to prepare the uniformly mixed material for tabletting. Multi-component synergistic
lipid lowering,
hepatocyte repairing and anti-oxidation and anti-inflammatory effects are adopted, the
bioavailability is improved by matching with the nano-carrier and a gradient release technology, the liver protection and
lipid lowering effects are remarkable, the storage stability is high, and the composition is suitable for long-term conditioning of people with
fatty liver.