The invention discloses a clinical medicine laboratory instrument management system and a standardized management method therefor. The management system comprises a system setting module, a device purchase application module, a device file module, an instruction module, a personnel authorization module, a maintenance module, a device calibration module, a project calibration module, a quality control report module, a fault maintenance module, an adverse event module, and a message reminding module. The method provided by the invention can achieve the setting of the accounts, roles and authorities of device administrative departments and users, the setting of the device purchase application and adverse event reports according to the management systems of hospitals and departments, and achieves the building of device management environments. Therefore, the method achieves a series of record and management paths: device purchase application and filing, instructions, personnel authorization, maintenance, device calibration, performance evaluation, calibration and quality control, fault management and adverse event report, and achieves the convenient and efficient comprehensive management of the instruments in a clinical laboratory.