The invention relates to a leather sole, and concretely relates to an injection molded leather sole and a making method thereof. The injection molded leather sole comprises plastic styrene butadiene rubber, hydrogenated styrene-butadiene-styrene segmented copolymer, ethylene-butylene copolymer, ethylene propylene diene monomer, white carbon black, talcum powder, naphthenic rubber oil, stearic acid, zinc stearate, zinc oxide, PEG4000, polysiloxane resin and dicumyl peroxide. The method comprises the following steps: mixing raw materials except dicumyl peroxide, carrying out first stage internal mixing, adding dicumyl peroxide when the temperature reaches 110-113DEG C, carrying out second stage internal mixing to obtain a well mixed mixture when the temperature rises to 115-118DEG C, thinning twice, and granulating; standing, injection the obtained material into a shoe die, and molding under the following conditions: the temperature of the is 178-182DEG C, and the vulcanizing time is 230-270s; and carrying out cooling molding on the above obtained sole to obtain the injection molded leather sole.