The invention relates to an insertion frame device with a self-locking insertion disc. The insertion frame device comprises an insertion card, wherein a clamping seat assembly structure and a flat handle are arranged on the insertion card, a clamping seat assembly is arranged on a side surface of the insertion card, the flat handle is arranged on the other side surface of the insertion card and isparallel to a bottom surface of the insertion card, a spherical bulge is arranged at the top of the insertion card and is provided with a compensation gap, a clamping seat, a handle, a floating blockand a spring are arranged on the clamping seat assembly, the handle can rotate around a rotation shaft arranged on the clamping seat within a certain amplitude range, an insertion card slot is formedin each insertion card slot position at the bottom of the insertion frame and is used for limiting an assembly correction position of the insertion card, a folded edge is arranged at a front end of the bottom of the insertion frame, insertion of the insertion card is facilitated, the locking reliability is improved, and guide rails are arranged at two sides of an internal slot position of the insertion frame and are used for guiding the insertion card to slide. The insertion frame has the advantages of high service integration, high assembly efficiency and reliable locking performance, the space of an equipment panel can be fully utilized, and the defect in the existing scheme is overcome.