33results about How to "Realize directional delivery" patented technology

A process for preparing the super-paramagnetic nanoparticles dispersed in water easily includes such steps as mixing the polymer chelating agent with Fe ions, dripping alkali while reacting to generate inn oxide and continuously dripping alkali until pH=9-10.

The invention relates to a composition with a skin whitening effect, a skin-whitening soluble micro-needle patch with high drug loading capacity, and a preparation method of the skin-whitening solublemicro-needle patch. The composition with the skin whitening effect comprises, by weight, 10-20 parts of arbutin, 10-20 parts of magnesium ascorbyl phosphate, 5-10 parts of adenosine, and 0.1-0.5 partof a sturgeon caviar. The skin-whitening soluble micro-needle patch comprises a pinpoint and a substrate, and the pinpoint is prepared from the composition with the skin whitening effect, hyaluronicacid or sodium hyaluronate, and a micro-needle auxiliary material, wherein the mass ratio of the composition with the skin whitening effect to hyaluronic acid or sodium hyaluronate to the micro-needleauxiliary material is 1 to 0.1-5 to 0.2-1; and the micro-needle auxiliary material is composed of polyvinylpyrrolidone, glycerol and hydroxypropyl cellulose. The skin-whitening soluble micro-needle patch has the high drug loading capacity, excellent mechanical performance, and good effects of skin whitening, spot fading and moisture preserving.

The invention discloses a targeted drug composition for co-loading amphotericin B and adriamycin and an application of the targeted drug composition, and belongs to the fields of medicines and pharmaceutics, and provides a novel medical composition for treating leishmaniasis. Two medicines of amphotericin B and adriamycin having fluorescent tracing properties are used and loaded in a pharmaceutical carrier material which is favorable in biological safety and has pH responsiveness to form the medical composition, wherein the carrier material consists of hydrophilicity mannose residues which actively target macrophages, beta-cyclodextrin and hydrophobic propionyl. The medical composition is good in biological safety (cytotoxicity and hemolytic activity), and the stability, pH response medicine release properties, target capacity, and treatment efficiency are verified in a cell model. Besides, the synergistic reaction of the amphotericin B and the adriamycin is realized, so that the consumption of the medicine is greatly reduced, the side effect is reduced, the economic burden of patients is alleviated, and the targeted drug composition is hopeful to exert great effects on clinical application.

The invention discloses an inner channel type seed taking and direction changing device and an on-film garlic planting machine, solves the problems that a garlic seed metering device in the prior artis unstable in work and cannot guarantee planting upright degrees of garlic, and has the advantages of achieving directional sowing and improving the planting upright degrees of garlic seeds. The specific scheme is as follows: the inner channel type seed taking and direction changing device comprises a seed box, a garlic groove and at least one seed taking and direction changing unit, wherein thesize of the top of the seed box is larger than that of the bottom of the seed box, the whole garlic groove is arc-shaped, the garlic groove is formed below the seed box, the seed box and the garlic groove are located on one side of the at least one seed taking and direction changing unit, the adjacent seed taking and direction changing units are connected, each seed taking and direction changing unit comprises a rotatable seed taking disc and seed taking spoons arranged in the circumferential direction of the seed taking disc, a plurality of conveying pipes are supported through the seed taking disc, direction turning pipes are fixed to a rack, the size of one side of the transverse section of a garlic seed turning channel in each direction turning pipe is larger than that of the other side, and each direction turning pipe and the conveying pipes on the top end side and the bottom end side of the direction turning pipe can be located on a same straight line.

The invention belongs to the technical fields of agricultural production planting and agricultural product processing, and particularly relates to a sugarcane seed steam bud calibration system. The system comprises a positioning and conveying device, a calibration object, a marking device, a cutting device and a collecting device; the positioning and conveying device is configured to make the sugarcane stem conveyed in a fixed posture, the marking device and the cutting device are sequentially arranged above the positioning and conveying device, the marking device is used for fixing the calibration object on the sugarcane seed stem, the cutting device is used for cutting the calibrated sugarcane seed stem to form small segments, and the collecting device is arranged at the end of the positioning and conveying device and is used for collecting the processed sugarcane seed stem. The calibration object and the stem buds of the sugarcane seed stem are arranged according to a specific position relationship, and the calibration object can be captured or recognized by a seeder, so the seeder can distinguish the positions of the stem buds on the sugarcane seed stem in order to realize thedirectional transportation and seeding of the sugarcane seed stem.

A process for preparing the gas-contained lipid or gas-contained composite lipid particles includes such steps as preparing the suspension of lipid or composite lipid particles from one or more ions, removing free ions, adding another solution of one or more ions to be reacted, regulating temp and pH value, mixing, and chemical reacting, another process is also disclosed.

The invention relates to a robot assembling section for a box body and a cross beam of a disinfection cabinet production line. The robot assembling section comprises a feeding mechanical hand, a positioning conveying line, a secondary positioning table, a box body assembly line and a cross beam screw driving machine. The positioning conveying line is used for positioning the cross beam grabbed bythe feeding mechanical hand. Multiple first positioning air cylinders are arranged on the top of the secondary positioning table and are used for conducting secondary positioning on the cross beam. The box body assembly line is used for conveying the box body to the cross beam screw driving machine. The cross beam screw driving machine is used for positioning the box body and the cross beam and used for driving screws on the cross beam on the box body so that the cross beam can be fixed on the box body. By means of the robot assembling section for the box body and the cross beam of the disinfection cabinet production line, a cross beam tool vehicle, the feeding mechanical hand, the positioning conveying line, the secondary positioning table, a material sending mechanical hand, a cross beamfeeding robot, the box body assembly line and the cross beam screw driving machine are used for achieving the processes of cross beam feeding, positioning, applying, screw driving and the like, and therefore the cross beam can be automatically installed on the box body of a disinfection cabinet, the production efficiency is greatly improved, an the production cost is reduced.

The invention relates to the technical field of food processing equipment, and discloses a seismic pendulum type conveying mechanism, and is used for conveying flat round or approximately pear-shapedarticles. The mechanism comprises racks, a fixed seat, a conveying groove, an elastic connecting mechanism and a driving mechanism used for driving the conveying groove to swing left and right, and avibration device used for driving the elastic connecting mechanism to vibrate; one side of the conveying groove is connected with the fixing base through a rotating shaft, the other side is hinged tothe driving mechanism, and the fixing base and the driving mechanism are connected with the racks through the elastic connecting mechanism; the conveying groove comprises an inlet and an outlet and isinclined from the inlet to the outlet; and the conveying groove and the object size conveyed by the conveying groove have to meet the following conditions that the two sides of the long axis direction of the article are correspondingly abutted against the inner walls of the two sides of the conveying groove, and the bottoms of the long-axis direction of the objects are in contact connection withthe bottom of the conveying groove. The mechanism has the advantages that the structure is simple, the operation is convenient, and the long shaft of the objects located in the mechanism can tend to be parallel in the vibration swinging process according to the length method of the conveying groove, so that directional conveying is achieved.

The invention discloses a pneumatic pollination control device and method for seed production of hybrid rice with a large ration of male and female parents. The device comprises a bottom plate, fans,a wind speed sensor, an airflow adapter, fan drivers, a processing chip, a wireless transmission module, an electronic compass module, an integrated circuit board, an upper cover and a touch screen, wherein each fan is driven by independent fan driver; the wireless transmission module receives environmental natural wind speed and wind direction information; the electronic compass module determinesthe advancing direction of a pollination machine; after a controller calculates a target output wind speed, the processing chip calculates in real time according to a preset algorithm to obtain a corrected wind speed, so that pollen floats to a target area; the wind speed sensor detects the wind speed of a wind outlet and transmits the wind speed back to the processing chip in real time to form closed-loop control; and the pollination machine can still enable the operating pollen to move in a target state under the condition of the disturbance of external natural wind. The pneumatic pollination control device is simple and compact in overall structure, simple in interaction and high in reliability, and a fan control device with excellent performance is provided for the pneumatic pollination machine of the hybrid rice.

The invention discloses a glass magnetic piston; it includes glass part and electromagnetic driving part. For glass part, glass piston with fixed magnetic core in it, set in glass pump body. Left end of glass pump connects to the glass grinding port of glass combination unidirectional valve. Right end of glass pump connects to the glass interface of glass combination unidirectional valve. Glass pumps body through the first and second electromagnetic coil. The invention is used in driving gas cycle; it has good air tightness, easy connection with glass device, and can run under high suction pressure.

The invention discloses a targeted nano-composite and a preparation method and application thereof, and the targeted nano-composite comprises a nano-carrier, biological targeted molecules, radioisotopes and a synergistic treatment functional substance; the biological targeting molecule is in coupling connection with the nano-carrier; the synergistic treatment functional substance is loaded in the nano-carrier; the radioactive isotope is carried on the nano-carrier. The targeted nano compound provided by the invention has a tumor targeted treatment effect, and by modifying an existing anti-cancer nano preparation, the selectivity of a drug to tumor tissues is improved, directional delivery and gradual release of the drug are realized, the metabolic kinetics and physicochemical properties of the drug are improved, and the toxic and side effects of the drug are reduced. Meanwhile, combined treatment of radioisotope treatment and chemotherapy or photothermal treatment or photodynamic treatment or sonodynamic treatment or magnetic thermal treatment can be achieved, and the problem that a good effect is difficult to generate through single chemotherapy is solved.

The invention belongs to the technical field of agricultural production planting and agriculture product processing, and particularly relates to a calibration method of sugarcane seed stem buds. Calibration objects are added on sugarcane seed stems through a sugarcane seed stem bud calibration system; the calibration objects and the sugarcane seed stem buds are distributed according to a specificposition relation; the calibration objects can be captured or identified through a sower. As the calibration objects and the sugarcane seed stem buds are distributed according to a specific position relation, and the calibration objects can be captured or identified through the sower, sowing equipment can recognize positions of the buds on the sugarcane seed stems, and further realizes the directional conveying and sowing of the sugarcane seed stems.

The invention discloses an automatic portable cable transmission robot. A servo motor is connected to one end of a ball screw, and the other end of the ball screw is installed on a base. The ball screw is fitted with a screw nut fixedly mounted on a slide. In the table, the light rods located on both sides of the ball screw pass through the slide table and both ends are installed on the base, and the slide table is equipped with a mechanical arm. The present invention realizes the automatic transmission of the cable by using the servo motor and the ball screw, which greatly reduces the manual use; through the mechanical arm with the one-way transmission function and the self-adapting outer diameter function, the directional transmission of the cable is realized, and the efficiency is improved; Stand-alone control or online coordination of multiple institutions can adapt to different working conditions and freely match according to actual needs; use wired or wireless remote control to coordinate multiple institutions in a unified manner, adjust the number, speed, operation mode and other indicators of institutions, and ensure that each The synchronous action of the mechanism improves the work efficiency.

The invention provides a screwdriver cap over-molding device. The screwdriver cap over-molding device comprises a screwdriver cap conveying device, a screwdriver cap arranging and locating device, a material transferring device and an injection molding device. The screwdriver cap conveying device conveys screwdriver caps and quantitatively arranges the screwdriver caps according to one array unit.The screwdriver cap arranging and locating device is used for arranging the multiple workpieces in array. The material transferring device transfers the workpieces arranged in array to the injectionmolding device as a whole. The injection molding device receives the workpieces transferred by the material transferring device and conducts over-molding. Compared with the prior art, the screwdrivercap over-molding device can automatically arrange the multiple screwdriver caps in array and conducts over-molding on the screwdriver caps arranged in array. The screwdriver cap over-molding device has the advantages of being high in automation degree, rapid in production speed and the like.