46results about How to "Has superparamagnetic properties" patented technology

The invention discloses a nano-drug carrier with the magnetothermal and photothermal effects. The particle size is 50 nanometers to 300 nanometers, and the nano-drug carrier is prepared from mesoporous silica particles, Fe3O4 nanoparticles embedded into the mesoporous silica particles and graphene oxide with which the surfaces of the mesoporous silica particles are coated. The invention further provides a preparation method of the nano-drug carrier. The superparamagnetic Fe3O4 nanoparticles are prepared through a solvothermal method, the Fe3O4 nanoparticles are composited by taking hexadecyl trimethyl ammonium bromide as a structure-directing agent and taking tetraethoxysilane as a silicon source through the sol-gel self-assembling process, and then magnetic mesoporous nanoparticles Fe3O4 / mSiO2 with the magnetic property adjustable and controllable are prepared; the surfaces of the Fe3O4 / mSiO2 mesoporous nanoparticles are coated with graphene through the ion interaction or electrostatic interaction or hydrogen-bond interaction, and then the nano-drug carrier which both can efficiently deliver anti-cancer drugs and has the magnetothermal and photothermal effects is obtained. Accordingly, cancer treatment in which medical chemotherapy cooperates with magnetothermal and photothermal treatment can be achieved.

The invention discloses a ferromagnetic urea-formaldehyde resin microsphere medium and a preparation method thereof, belonging to the technology of magnetic resin microsphere medium. The base material of the microsphere medium is a urea-formaldehyde resin with a particle size of 0.5-20 μm, and Fe with a particle size of 0.1-200 nm is uniformly dispersed in the base material. 3 O 4 of nanoparticles. The preparation method adopts superparamagnetic metal oxide, urea and formaldehyde, and the preparation process includes the preparation of magnetic fluid, the peptization and separation of magnetic fluid, and the preparation of magnetic microspheres. The advantage of the present invention is that the prepared microspheres have superparamagnetic properties, Fe 3 O 4 The magnetic nanoparticles are completely coated with urea-formaldehyde resin, which avoids the poisoning effect on the separation system. The particle size distribution of the magnetic particles is uniform, the sedimentation rate in the magnetic field is consistent, and the surface is easy to be modified. The preparation method has the advantages of simple operation, easy process control, low raw material cost, good product stability and easy industrial production.

The invention provides a superparamagnetic nanosphere and a preparation method thereof, comprising SiO2 nanoparticles, a Fe3O4 layer and a SiO2 layer, the Fe3O4 layer uses SiO2 nanoparticles as a template to form a shell layer by in-situ growth of Fe3O4 nanoparticles, and the SiO2 layer is deposited on the outer surface of the Fe3O4 layer to form a cladding layer. The superparamagnetic nanospheres use colloidal SiO2 nanoparticles as templates, so that the size of SiO2@Fe3O4@SiO2 nanospheres can be adjusted by changing the size of template SiO2 nanoparticles; by in-situ growth on the surface of template SiO2 nanoparticles Coating Fe3O4 nanoparticles by means of a method greatly increases their loading density and simplifies the synthesis conditions. At the same time, the stability of Fe3O4@SiO2 nanospheres can be significantly improved by coating the outer surface of Fe3O4 layer with SiO2.

A method for preparing gold-coated nano-magnetic particles for preparing magnetic liquids, the method comprising: chloroauric acid and sodium citrate at a mass ratio of ferric oxide nano-magnetic particles to chloroauric acid of 1:10 to 1:0.5 The mass ratio of 1:36.9~1:7.4 or the mass ratio of chloroauric acid and hydroxylamine hydrochloride 1:5.6~1:2 is weighed and prepared; the solution is made according to the weighed chloroauric acid, hydroxylamine hydrochloride and sodium citrate. Dissolve ferric oxide nano-magnetic particles in absolute ethanol and disperse completely by ultrasonic. Add 3-aminopropyltriethoxysilane and iron ferric oxide nano-magnetic particles, the ratio of volume to mass is 1:1-4:1, and continue to sonicate. Add the configured chloroauric acid solution and ultrasonicate for 1h. Adding sodium citrate solution and hydroxylamine hydrochloride solution, ultrasonication for 6 hours, separation, washing, ultrasonic cleaning with dilute hydrochloric acid for 1 hour, separation and drying, to prepare gold-coated nano-magnetic particles. The corrosion resistance of magnetic fluids prepared from gold-coated particles is enhanced.

The invention belongs to a preparation method for micron-sized superparamagnetic ferroferric oxide microspheres. A two-step seed growth method is adopted for controlling synthesis, namely nanometer particles generated by a solution A are used as seeds, a solution B is used as mother liquor for subsequent growth, and the ratio of the nanometer particles to the solution B and the temperatures of the nanometer particles and the solution B are controlled to regulate and control the sizes of the superparamagnetic ferroferric oxide microspheres. The sizes of the prepared micron-sized superparamagnetic ferroferric oxide microspheres are ranged from 500 to 2,500nm, and the prepared ferroferric oxide microspheres are high in dispersibility and uniform in particle size, and have superparamagnetism.

The invention provides a detection method for rapidly detecting vibrio parahaemolyticus. According to the scheme, bacteria are enriched by Fe3O4 / Ru(bqy) 3<2+> microspheres, a test strip is prepared, and a sample is loaded for detection. The step of eluting the vibrio parahaemolyticus from immunomagnetic beads is eliminated, so that the capturing efficiency is improved; the step of spraying the Fe3O4 / Ru(bqy) 3<2+> microspheres onto a conjugate pad is eliminated, so that immunological reaction is more uniform, and a variation coefficient during quantitative detection is small; the workload and the sundry fungus contamination probability are reduced; the detection scheme is high in sensitivity and stability.

The invention discloses a method for in-situ preparing super-paramagnetic Fe3O4 nanotube arrays by atomic layer deposition, and belongs to the technical field of preparation of nanotube arrays. The method comprises the following steps: 1) conveying a clean AAO (Anodic Aluminum Oxide) substrate into an atomic layer deposition device for later use; 2) charging ferrocene steam and oxygen into a gas carrying system of the atomic layer deposition device, conveying into a vacuum reaction cavity through the gas carrying system, starting atomic layer deposition circulation under the nitrogen atmosphere, and repeating the circulation until uniform Fe3O4 films are generated on the surface and holes of the AAO substrate; 3) polishing to remove the Fe3O4 film on the surface of the AAO substrate; 4) dissolving to remove the AAO substrate through aqueous alkali to obtain orderly-arranged Fe3O4 nanotube arrays. The method is simple to operate, wide in raw material source, and easy to be achieved; the super-paramagnetic Fe3O4 nanotube arrays which are very large in aspect ratio, are orderly arranged and are very uniform in shape and size can be obtained by in-situ growth.

The invention relates to magnetic composite microspheres, and a preparation method and application thereof, belonging to the technical field of chemical material preparation. The preparation method comprises the following steps: synthesizing Fe3O4@SiO2-MPS (modified polystyrene); mixing, adding acetonitrile, carrying out ultrasonic dispersion, adding isopropyl acrylamide, glycidyl methacrylate, N,N'-methylene-bis acrylamide and azodiisobutyronitrile, mixing, and carrying out oil-bath heating; distilling to obtain part of acetonitrile, and stopping the reaction; carrying out magnetic separation on the obtained, and repeatedly washing with ethanol and water; and drying in a vacuum drying oven to obtain the product. The product is used for cellulase immobilization. The synthesized magnetic composite microspheres have superparamagnetism, can enhance the enzyme activity restorability and heat stability when being used for cellulase immobilization, and implements thermal protection on the cellulase.

The invention discloses a magnetic composite catalyst Zn 0 / Fe 3 o 4 And its preparation method and application. The method for preparing the composite catalyst comprises: in an inert atmosphere, mixing ferric iron tetroxide and zinc salt in a solvent according to the stated ratio with an aqueous solution of sodium borohydride to carry out a reduction reaction, and drying the obtained precipitate after the reaction is completed to obtain the obtained the composite catalyst. The invention overcomes the deficiencies in the prior art and provides a magnetic composite catalyst Zn with simple preparation, cheap raw materials and high catalytic activity. 0 / Fe 3 o 4 And the preparation method, the catalyst can significantly improve the removal efficiency of crystal violet in the Fenton-like reaction.