According to a TCON drive circuit applied to a notebook computer, a power supply module, a main control module, a storage module, a brightness adjusting module and an output module are arranged. In the actual application process, due to the fact that the output module comprises the multiple output units, the output units can input processed LVDS signals to the display screen, the display screen can receive more image information, the imaging definition of the display screen is improved, and the resolution of the display screen is guaranteed; besides, the main control module comprises an anti-surge unit, and the anti-surge unit can absorb surge current, so that the circuit is effectively prevented from being damaged by overlarge surge current, and the circuit cannot work normally. Furthermore, due to the arrangement of the brightness adjusting module, when the display screen needs brightness adjustment, the brightness adjusting module outputs related signals to the display screen. The display screen automatically adjusts the brightness.