The invention discloses a full-assembly detachable building structure and an installation and construction technology, and relates to the field of building structures. The structure comprises a pile foundation hole formed in a foundation, a pile foundation is installed in the pile foundation hole, a foundation beam is installed above the pile foundation, a prefabricated house structure is installed on the foundation beam, and the prefabricated house structure comprises a load bearing gable wall, load bearing front and rear walls, a load bearing partition wall and a floor plate or a roof plate; according to the installation sequence, the load bearing front and back walls are installed, then the load bearing gable wall is installed, then, the load bearing partition wall is installed, and the floor plate or the roof plate is installed. The body building components of the full-assembly detachable building structure can be industrialized produced, a building can be detached and recycled, the labor intensity is lowered, the building construction speed is increased, the cost is lowered, the intensity of the house is ensured, and energy conservation and environmental protection are achieved while it is ensured that the intensity of the house achieves the anti-seismic performance.