The invention belongs to the technical field of agriculture, and particular discloses a method for cultivating selenium-rich sweet potatoes. The method comprises the steps of land selection, seed selection, sowing, field management and pest control. According to field management, intertillage weeding and topdressing, reasonable irrigation and ridging are included; according to topdressing, selenium-rich organic fertilizer and selenium-rich leaf fertilizer are dressed, and 2 kg to 4 kg of the organic fertilizer and 1 kg to 2 kg of the leaf fertilizer are applied to each sweet potato. The organic fertilizer and the leaf fertilizer are applied together, growth of the sweet potatoes can be promoted, and the planting period can be shortened. During intertillage, the tubers of the sweet potatoes begin to grow, tuber growing is a guarantee of yield increasing, and therefore organic fertilizer application is critical during intertillage. According to the method, the organic fertilizer and the leaf fertilizer which can promote tuber growth and add selenium into the tubers are specially designed for the sweet potatoes, therefore, it is guaranteed that the sweet potatoes can absorb and utilize sufficient selenium in the whole growth process, the yield of the sweet potatoes is increased, and selenium in the sweet potatoes can be increased.